(43 nodes) Cortical actin cytoskeleton network (Gloeophyllum trabeum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	S7QCB0_GLOTA	BAR-domain-containing protein. (264 aa)
	S7QLR8_GLOTA	ANTH-domain-containing protein. (1072 aa)
	S7QKU6_GLOTA	Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1283 aa)
	S7QKA0_GLOTA	DNase I-like protein. (1218 aa)
	S7Q3V5_GLOTA	Uncharacterized protein. (174 aa)
	S7Q3P9_GLOTA	Actin-like protein Arp3; Belongs to the actin family. (430 aa)
	S7Q0R0_GLOTA	Calponin. (651 aa)
	S7PXX9_GLOTA	WD40 repeat-like protein. (600 aa)
	S7PX47_GLOTA	ArfGap-domain-containing protein. (470 aa)
	S7PVS9_GLOTA	DUF2013 domain-containing protein. (636 aa)
	S7PVB5_GLOTA	EF-hand. (141 aa)
	S7PUR3_GLOTA	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (292 aa)
	S7PUQ0_GLOTA	Uncharacterized protein. (655 aa)
	S7PTI8_GLOTA	Uncharacterized protein. (1887 aa)
	S7PTH7_GLOTA	Actinin-like protein. (622 aa)
	S7QK47_GLOTA	Tyrosine protein phosphatase. (664 aa)
	S7QJR9_GLOTA	C2 domain-containing protein. (715 aa)
	S7QG78_GLOTA	Adenylyl cyclase-associated protein; Belongs to the CAP family. (519 aa)
	S7QFU2_GLOTA	Glia maturation factor beta. (140 aa)
	S7QE46_GLOTA	Uncharacterized protein. (73 aa)
	S7QDN5_GLOTA	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (403 aa)
	S7QD80_GLOTA	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (170 aa)
	S7Q9L8_GLOTA	Coronin; Belongs to the WD repeat coronin family. (527 aa)
	S7Q9Z7_GLOTA	RhoGAP-domain-containing protein. (685 aa)
	S7RSY0_GLOTA	Uncharacterized protein. (648 aa)
	S7RTB5_GLOTA	Actin filament-coating protein tropomyosin. (161 aa)
	S7RU63_GLOTA	Uncharacterized protein. (1296 aa)
	S7RUB8_GLOTA	Clathrin-link domain-containing protein. (1669 aa)
	S7RW84_GLOTA	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (179 aa)
	S7RYS6_GLOTA	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (687 aa)
	S7S0G1_GLOTA	Uncharacterized protein. (1162 aa)
	S7S3F5_GLOTA	VHS domain-containing protein. (498 aa)
	S7S518_GLOTA	DUF500-domain-containing protein. (523 aa)
	S7S5H0_GLOTA	BAR-domain-containing protein. (433 aa)
	S7RQT7_GLOTA	Uncharacterized protein. (920 aa)
	S7RP30_GLOTA	DUF500-domain-containing protein. (277 aa)
	S7RNT6_GLOTA	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (391 aa)
	S7RKV1_GLOTA	Uncharacterized protein. (874 aa)
	S7RI08_GLOTA	ADF-like domain-containing protein. (144 aa)
	S7RGA0_GLOTA	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2340 aa)
	S7REH6_GLOTA	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (266 aa)
	S7RAD0_GLOTA	WH1-domain-containing protein. (247 aa)
	S7R9Z0_GLOTA	Actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (130 aa)

Your Current Organism:

Gloeophyllum trabeum

NCBI taxonomy Id: 670483
Other names: G. trabeum ATCC 11539, Gloeophyllum trabeum ATCC 11539

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S7PTH7_GLOTA	S7PVB5_GLOTA	S7PTH7	S7PVB5	Actinin-like protein.	EF-hand.	0.563
S7PTH7_GLOTA	S7R9Z0_GLOTA	S7PTH7	S7R9Z0	Actinin-like protein.	Actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.	0.955
S7PTH7_GLOTA	S7REH6_GLOTA	S7PTH7	S7REH6	Actinin-like protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.728
S7PTH7_GLOTA	S7RGA0_GLOTA	S7PTH7	S7RGA0	Actinin-like protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.875
S7PTH7_GLOTA	S7RNT6_GLOTA	S7PTH7	S7RNT6	Actinin-like protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.499
S7PTH7_GLOTA	S7RTB5_GLOTA	S7PTH7	S7RTB5	Actinin-like protein.	Actin filament-coating protein tropomyosin.	0.782
S7PUQ0_GLOTA	S7PVS9_GLOTA	S7PUQ0	S7PVS9	Uncharacterized protein.	DUF2013 domain-containing protein.	0.704
S7PUQ0_GLOTA	S7Q9L8_GLOTA	S7PUQ0	S7Q9L8	Uncharacterized protein.	Coronin; Belongs to the WD repeat coronin family.	0.425
S7PUQ0_GLOTA	S7QCB0_GLOTA	S7PUQ0	S7QCB0	Uncharacterized protein.	BAR-domain-containing protein.	0.608
S7PUQ0_GLOTA	S7QKU6_GLOTA	S7PUQ0	S7QKU6	Uncharacterized protein.	Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.815
S7PUQ0_GLOTA	S7QLR8_GLOTA	S7PUQ0	S7QLR8	Uncharacterized protein.	ANTH-domain-containing protein.	0.487
S7PUQ0_GLOTA	S7RAD0_GLOTA	S7PUQ0	S7RAD0	Uncharacterized protein.	WH1-domain-containing protein.	0.977
S7PUQ0_GLOTA	S7RNT6_GLOTA	S7PUQ0	S7RNT6	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.582
S7PUQ0_GLOTA	S7RQT7_GLOTA	S7PUQ0	S7RQT7	Uncharacterized protein.	Uncharacterized protein.	0.758
S7PUQ0_GLOTA	S7RSY0_GLOTA	S7PUQ0	S7RSY0	Uncharacterized protein.	Uncharacterized protein.	0.531
S7PUQ0_GLOTA	S7RU63_GLOTA	S7PUQ0	S7RU63	Uncharacterized protein.	Uncharacterized protein.	0.523
S7PUQ0_GLOTA	S7RUB8_GLOTA	S7PUQ0	S7RUB8	Uncharacterized protein.	Clathrin-link domain-containing protein.	0.640
S7PUQ0_GLOTA	S7S0G1_GLOTA	S7PUQ0	S7S0G1	Uncharacterized protein.	Uncharacterized protein.	0.658
S7PUQ0_GLOTA	S7S5H0_GLOTA	S7PUQ0	S7S5H0	Uncharacterized protein.	BAR-domain-containing protein.	0.629
S7PUR3_GLOTA	S7PXX9_GLOTA	S7PUR3	S7PXX9	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	WD40 repeat-like protein.	0.589