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I4Y559_WALMC | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (318 aa) | ||||
I4Y567_WALMC | DNA repair protein rad10. (317 aa) | ||||
I4Y587_WALMC | WD40 repeat-like protein. (1048 aa) | ||||
I4Y5B8_WALMC | Pkinase-domain-containing protein. (578 aa) | ||||
I4Y5K5_WALMC | Uncharacterized protein. (443 aa) | ||||
I4Y5S5_WALMC | Origin recognition complex subunit 2. (393 aa) | ||||
I4Y691_WALMC | DNA mismatch repair protein MutL. (678 aa) | ||||
I4Y6G0_WALMC | DNA ligase. (643 aa) | ||||
I4Y6J7_WALMC | DNA helicase; Belongs to the MCM family. (929 aa) | ||||
I4Y6K8_WALMC | DNA polymerase alpha, subunit B. (560 aa) | ||||
I4Y6X5_WALMC | DNA repair protein. (302 aa) | ||||
I4Y7A9_WALMC | Zf-primase domain-containing protein. (580 aa) | ||||
I4Y7B3_WALMC | DBF4-type domain-containing protein. (967 aa) | ||||
I4Y7C9_WALMC | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (253 aa) | ||||
I4Y7G3_WALMC | Uncharacterized protein. (798 aa) | ||||
I4Y7Q5_WALMC | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2211 aa) | ||||
I4Y834_WALMC | DNA mismatch repair protein Msh6; Component of the post-replicative DNA mismatch repair system (MMR). (1017 aa) | ||||
I4Y848_WALMC | GINS complex, Psf3 component. (173 aa) | ||||
I4Y8R5_WALMC | DNA polymerase. (1060 aa) | ||||
I4Y8S6_WALMC | UV excision repair protein Rad23. (336 aa) | ||||
I4Y8Z9_WALMC | Kinase-like protein. (496 aa) | ||||
I4Y912_WALMC | Uncharacterized protein. (427 aa) | ||||
I4Y918_WALMC | Uncharacterized protein. (214 aa) | ||||
I4Y967_WALMC | Checkpoint protein Rad24. (488 aa) | ||||
I4YA88_WALMC | Pkinase-domain-containing protein. (265 aa) | ||||
I4YAM3_WALMC | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (496 aa) | ||||
I4YAW9_WALMC | MRC1 domain-containing protein. (1111 aa) | ||||
I4YAX6_WALMC | P-loop containing nucleoside triphosphate hydrolase protein. (409 aa) | ||||
I4YBA9_WALMC | Uncharacterized protein. (508 aa) | ||||
I4YBG9_WALMC | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1091 aa) | ||||
I4YBR1_WALMC | RNI-like protein. (555 aa) | ||||
I4YBW2_WALMC | Origin recognition complex, subunit 4. (473 aa) | ||||
I4YC05_WALMC | DNA helicase; Belongs to the MCM family. (728 aa) | ||||
I4YC07_WALMC | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (672 aa) | ||||
I4YC37_WALMC | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (599 aa) | ||||
I4YCC0_WALMC | Uncharacterized protein. (861 aa) | ||||
I4YCV1_WALMC | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (873 aa) | ||||
I4YCY9_WALMC | DNA helicase; Belongs to the MCM family. (888 aa) | ||||
I4YD02_WALMC | Uncharacterized protein. (432 aa) | ||||
I4YD30_WALMC | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2030 aa) | ||||
I4YD80_WALMC | Histone-fold-containing protein. (152 aa) | ||||
I4YD86_WALMC | AAA domain-containing protein. (459 aa) | ||||
I4YDA0_WALMC | Timeless-domain-containing protein. (890 aa) | ||||
I4YDE5_WALMC | DNA supercoiling. (806 aa) | ||||
I4YDJ6_WALMC | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (797 aa) | ||||
I4YDK9_WALMC | Uncharacterized protein. (660 aa) | ||||
I4YDL8_WALMC | ERCC4 domain-containing protein. (965 aa) | ||||
I4YDY1_WALMC | Rad4-domain-containing protein. (907 aa) | ||||
I4YE06_WALMC | DNA ligase; Belongs to the peptidase T1A family. (943 aa) | ||||
I4YE47_WALMC | P-loop containing nucleoside triphosphate hydrolase protein. (680 aa) | ||||
I4YE74_WALMC | DNA_MISMATCH_REPAIR_2 domain-containing protein. (809 aa) | ||||
I4YE77_WALMC | ATP-dependent DNA helicase. (1115 aa) | ||||
I4YEG0_WALMC | Replication protein A, subunit RPA32. (272 aa) | ||||
I4YEG6_WALMC | DNA replication factor C, large subunit. (753 aa) | ||||
I4YEK8_WALMC | DNA helicase; Belongs to the MCM family. (818 aa) | ||||
I4YF06_WALMC | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (206 aa) | ||||
I4YF71_WALMC | CDC45-like protein. (700 aa) | ||||
I4YFF0_WALMC | PIN domain-like protein. (649 aa) | ||||
I4YFL1_WALMC | Uncharacterized protein. (811 aa) | ||||
I4YFP1_WALMC | DNA_pol_E_B domain-containing protein. (821 aa) | ||||
I4YFP6_WALMC | Ribonuclease H-like protein. (337 aa) | ||||
I4YG30_WALMC | DUF1767 domain-containing protein. (213 aa) | ||||
I4YG63_WALMC | Uncharacterized protein. (916 aa) | ||||
I4YG67_WALMC | DNA clamp loader. (356 aa) | ||||
I4YG99_WALMC | ORC_WH_C domain-containing protein. (670 aa) | ||||
I4YGC8_WALMC | DNA helicase; Belongs to the MCM family. (890 aa) | ||||
I4YGG3_WALMC | GINS complex, Psf1 component. (212 aa) | ||||
I4YGR5_WALMC | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (416 aa) | ||||
I4YGU6_WALMC | P-loop containing nucleoside triphosphate hydrolase protein. (331 aa) | ||||
I4YH03_WALMC | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (906 aa) | ||||
I4YHD7_WALMC | P-loop containing nucleoside triphosphate hydrolase protein. (331 aa) | ||||
I4YHE2_WALMC | Pkinase-domain-containing protein. (578 aa) | ||||
I4YHS0_WALMC | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (635 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (433 aa) | ||||
I4YIW6_WALMC | PIN domain-like protein. (1046 aa) | ||||
I4YJ06_WALMC | Uncharacterized protein. (348 aa) | ||||
I4YJ16_WALMC | RECA_2 domain-containing protein. (52 aa) | ||||
I4YJ37_WALMC | Uncharacterized protein. (304 aa) | ||||
I4YJ44_WALMC | P-loop containing nucleoside triphosphate hydrolase protein. (335 aa) | ||||
I4YJ60_WALMC | Uncharacterized protein. (465 aa) | ||||
I4YJE6_WALMC | DNA polymerase. (1399 aa) | ||||
I4YJE7_WALMC | DNA/RNA polymerase. (584 aa) | ||||
I4YJH7_WALMC | Checkpoint protein; Belongs to the HUS1 family. (239 aa) | ||||
I4YJM9_WALMC | RRM domain-containing protein. (234 aa) | ||||
I4YJP4_WALMC | SAE2 domain-containing protein. (90 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (726 aa) | ||||
I4YJW5_WALMC | Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (262 aa) | ||||
I4YJX7_WALMC | DsRNA-binding domain-like protein. (137 aa) | ||||
I4YK15_WALMC | Histone-fold-containing protein. (170 aa) |