node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | I4Y6K8_WALMC | I4YIV5 | I4Y6K8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase alpha, subunit B. | 0.790 |
FEN1 | I4Y8R5_WALMC | I4YIV5 | I4Y8R5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.988 |
FEN1 | I4YAM3_WALMC | I4YIV5 | I4YAM3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. | 0.801 |
FEN1 | I4YBA9_WALMC | I4YIV5 | I4YBA9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.938 |
FEN1 | I4YGR5_WALMC | I4YIV5 | I4YGR5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.869 |
FEN1 | I4YJM9_WALMC | I4YIV5 | I4YJM9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | RRM domain-containing protein. | 0.840 |
I4Y6K8_WALMC | FEN1 | I4Y6K8 | I4YIV5 | DNA polymerase alpha, subunit B. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.790 |
I4Y6K8_WALMC | I4Y8R5_WALMC | I4Y6K8 | I4Y8R5 | DNA polymerase alpha, subunit B. | DNA polymerase. | 0.953 |
I4Y6K8_WALMC | I4YAM3_WALMC | I4Y6K8 | I4YAM3 | DNA polymerase alpha, subunit B. | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. | 0.999 |
I4Y6K8_WALMC | I4YBA9_WALMC | I4Y6K8 | I4YBA9 | DNA polymerase alpha, subunit B. | Uncharacterized protein. | 0.898 |
I4Y6K8_WALMC | I4YGR5_WALMC | I4Y6K8 | I4YGR5 | DNA polymerase alpha, subunit B. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.999 |
I4Y6K8_WALMC | I4YJM9_WALMC | I4Y6K8 | I4YJM9 | DNA polymerase alpha, subunit B. | RRM domain-containing protein. | 0.977 |
I4Y8R5_WALMC | FEN1 | I4Y8R5 | I4YIV5 | DNA polymerase. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.988 |
I4Y8R5_WALMC | I4Y6K8_WALMC | I4Y8R5 | I4Y6K8 | DNA polymerase. | DNA polymerase alpha, subunit B. | 0.953 |
I4Y8R5_WALMC | I4YAM3_WALMC | I4Y8R5 | I4YAM3 | DNA polymerase. | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. | 0.968 |
I4Y8R5_WALMC | I4YBA9_WALMC | I4Y8R5 | I4YBA9 | DNA polymerase. | Uncharacterized protein. | 0.999 |
I4Y8R5_WALMC | I4YGR5_WALMC | I4Y8R5 | I4YGR5 | DNA polymerase. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.950 |
I4Y8R5_WALMC | I4YJM9_WALMC | I4Y8R5 | I4YJM9 | DNA polymerase. | RRM domain-containing protein. | 0.850 |
I4YAM3_WALMC | FEN1 | I4YAM3 | I4YIV5 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.801 |
I4YAM3_WALMC | I4Y6K8_WALMC | I4YAM3 | I4Y6K8 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. | DNA polymerase alpha, subunit B. | 0.999 |