15 items (Wallemia mellicola) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I4Y7G3_WALMC	Uncharacterized protein. (798 aa)
	I4Y967_WALMC	Checkpoint protein Rad24. (488 aa)
	I4YC07_WALMC	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (672 aa)
	I4YC37_WALMC	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (599 aa)
	I4YD30_WALMC	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2030 aa)
	I4YDJ6_WALMC	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (797 aa)
	I4YE77_WALMC	ATP-dependent DNA helicase. (1115 aa)
	I4YEG0_WALMC	Replication protein A, subunit RPA32. (272 aa)
	I4YFF0_WALMC	PIN domain-like protein. (649 aa)
	I4YG30_WALMC	DUF1767 domain-containing protein. (213 aa)
	I4YJ37_WALMC	Uncharacterized protein. (304 aa)
	I4YJ60_WALMC	Uncharacterized protein. (465 aa)
	I4YJH7_WALMC	Checkpoint protein; Belongs to the HUS1 family. (239 aa)
	I4YJP4_WALMC	SAE2 domain-containing protein. (90 aa)
	I4YJX7_WALMC	DsRNA-binding domain-like protein. (137 aa)

Your Current Organism:

Wallemia mellicola

NCBI taxonomy Id: 671144
Other names: W. mellicola CBS 633.66, Wallemia mellicola CBS 633.66

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I4Y7G3_WALMC	I4Y967_WALMC	I4Y7G3	I4Y967	Uncharacterized protein.	Checkpoint protein Rad24.	0.881
I4Y7G3_WALMC	I4YC07_WALMC	I4Y7G3	I4YC07	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.700
I4Y7G3_WALMC	I4YC37_WALMC	I4Y7G3	I4YC37	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.829
I4Y7G3_WALMC	I4YD30_WALMC	I4Y7G3	I4YD30	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.976
I4Y7G3_WALMC	I4YDJ6_WALMC	I4Y7G3	I4YDJ6	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.680
I4Y7G3_WALMC	I4YE77_WALMC	I4Y7G3	I4YE77	Uncharacterized protein.	ATP-dependent DNA helicase.	0.867
I4Y7G3_WALMC	I4YEG0_WALMC	I4Y7G3	I4YEG0	Uncharacterized protein.	Replication protein A, subunit RPA32.	0.646
I4Y7G3_WALMC	I4YFF0_WALMC	I4Y7G3	I4YFF0	Uncharacterized protein.	PIN domain-like protein.	0.843
I4Y7G3_WALMC	I4YG30_WALMC	I4Y7G3	I4YG30	Uncharacterized protein.	DUF1767 domain-containing protein.	0.712
I4Y7G3_WALMC	I4YJ37_WALMC	I4Y7G3	I4YJ37	Uncharacterized protein.	Uncharacterized protein.	0.848
I4Y7G3_WALMC	I4YJ60_WALMC	I4Y7G3	I4YJ60	Uncharacterized protein.	Uncharacterized protein.	0.988
I4Y7G3_WALMC	I4YJH7_WALMC	I4Y7G3	I4YJH7	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.842
I4Y7G3_WALMC	I4YJP4_WALMC	I4Y7G3	I4YJP4	Uncharacterized protein.	SAE2 domain-containing protein.	0.699
I4Y7G3_WALMC	I4YJX7_WALMC	I4Y7G3	I4YJX7	Uncharacterized protein.	DsRNA-binding domain-like protein.	0.759
I4Y967_WALMC	I4Y7G3_WALMC	I4Y967	I4Y7G3	Checkpoint protein Rad24.	Uncharacterized protein.	0.881
I4Y967_WALMC	I4YC07_WALMC	I4Y967	I4YC07	Checkpoint protein Rad24.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.831
I4Y967_WALMC	I4YC37_WALMC	I4Y967	I4YC37	Checkpoint protein Rad24.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.859
I4Y967_WALMC	I4YD30_WALMC	I4Y967	I4YD30	Checkpoint protein Rad24.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.940
I4Y967_WALMC	I4YDJ6_WALMC	I4Y967	I4YDJ6	Checkpoint protein Rad24.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.761
I4Y967_WALMC	I4YE77_WALMC	I4Y967	I4YE77	Checkpoint protein Rad24.	ATP-dependent DNA helicase.	0.911