node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
I4YC37_WALMC | I4YDJ6_WALMC | I4YC37 | I4YDJ6 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.987 |
I4YC37_WALMC | I4YE77_WALMC | I4YC37 | I4YE77 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | ATP-dependent DNA helicase. | 0.993 |
I4YC37_WALMC | I4YEG0_WALMC | I4YC37 | I4YEG0 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | Replication protein A, subunit RPA32. | 0.999 |
I4YC37_WALMC | I4YG30_WALMC | I4YC37 | I4YG30 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DUF1767 domain-containing protein. | 0.986 |
I4YC37_WALMC | I4YJX7_WALMC | I4YC37 | I4YJX7 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DsRNA-binding domain-like protein. | 0.997 |
I4YDJ6_WALMC | I4YC37_WALMC | I4YDJ6 | I4YC37 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.987 |
I4YDJ6_WALMC | I4YE77_WALMC | I4YDJ6 | I4YE77 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent DNA helicase. | 0.998 |
I4YDJ6_WALMC | I4YEG0_WALMC | I4YDJ6 | I4YEG0 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A, subunit RPA32. | 0.879 |
I4YDJ6_WALMC | I4YG30_WALMC | I4YDJ6 | I4YG30 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DUF1767 domain-containing protein. | 0.998 |
I4YDJ6_WALMC | I4YJX7_WALMC | I4YDJ6 | I4YJX7 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DsRNA-binding domain-like protein. | 0.857 |
I4YE77_WALMC | I4YC37_WALMC | I4YE77 | I4YC37 | ATP-dependent DNA helicase. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.993 |
I4YE77_WALMC | I4YDJ6_WALMC | I4YE77 | I4YDJ6 | ATP-dependent DNA helicase. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.998 |
I4YE77_WALMC | I4YEG0_WALMC | I4YE77 | I4YEG0 | ATP-dependent DNA helicase. | Replication protein A, subunit RPA32. | 0.948 |
I4YE77_WALMC | I4YG30_WALMC | I4YE77 | I4YG30 | ATP-dependent DNA helicase. | DUF1767 domain-containing protein. | 0.982 |
I4YE77_WALMC | I4YJX7_WALMC | I4YE77 | I4YJX7 | ATP-dependent DNA helicase. | DsRNA-binding domain-like protein. | 0.971 |
I4YEG0_WALMC | I4YC37_WALMC | I4YEG0 | I4YC37 | Replication protein A, subunit RPA32. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.999 |
I4YEG0_WALMC | I4YDJ6_WALMC | I4YEG0 | I4YDJ6 | Replication protein A, subunit RPA32. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.879 |
I4YEG0_WALMC | I4YE77_WALMC | I4YEG0 | I4YE77 | Replication protein A, subunit RPA32. | ATP-dependent DNA helicase. | 0.948 |
I4YEG0_WALMC | I4YG30_WALMC | I4YEG0 | I4YG30 | Replication protein A, subunit RPA32. | DUF1767 domain-containing protein. | 0.883 |
I4YEG0_WALMC | I4YJX7_WALMC | I4YEG0 | I4YJX7 | Replication protein A, subunit RPA32. | DsRNA-binding domain-like protein. | 0.978 |