node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BNA1 | BNA5 | I4YC18 | I4YBS3 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.988 |
BNA1 | I4Y6Q4_WALMC | I4YC18 | I4Y6Q4 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | FAD/NAD(P)-binding domain-containing protein. | 0.866 |
BNA1 | I4YAD7_WALMC | I4YC18 | I4YAD7 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Indoleamine 2,3-dioxygenase. | 0.659 |
BNA1 | I4YF77_WALMC | I4YC18 | I4YF77 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.675 |
BNA5 | BNA1 | I4YBS3 | I4YC18 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | 0.988 |
BNA5 | I4Y6Q4_WALMC | I4YBS3 | I4Y6Q4 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | FAD/NAD(P)-binding domain-containing protein. | 0.996 |
BNA5 | I4YAD7_WALMC | I4YBS3 | I4YAD7 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Indoleamine 2,3-dioxygenase. | 0.964 |
BNA5 | I4YC16_WALMC | I4YBS3 | I4YC16 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.724 |
BNA5 | I4YCH1_WALMC | I4YBS3 | I4YCH1 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Anthranilate phosphoribosyltransferase. | 0.548 |
BNA5 | I4YF77_WALMC | I4YBS3 | I4YF77 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.644 |
BNA5 | I4YIS7_WALMC | I4YBS3 | I4YIS7 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Tryptophan synthase. | 0.719 |
I4Y6Q4_WALMC | BNA1 | I4Y6Q4 | I4YC18 | FAD/NAD(P)-binding domain-containing protein. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | 0.866 |
I4Y6Q4_WALMC | BNA5 | I4Y6Q4 | I4YBS3 | FAD/NAD(P)-binding domain-containing protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.996 |
I4Y6Q4_WALMC | I4YF77_WALMC | I4Y6Q4 | I4YF77 | FAD/NAD(P)-binding domain-containing protein. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.563 |
I4YAD7_WALMC | BNA1 | I4YAD7 | I4YC18 | Indoleamine 2,3-dioxygenase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | 0.659 |
I4YAD7_WALMC | BNA5 | I4YAD7 | I4YBS3 | Indoleamine 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.964 |
I4YAD7_WALMC | I4YF77_WALMC | I4YAD7 | I4YF77 | Indoleamine 2,3-dioxygenase. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.533 |
I4YAD7_WALMC | I4YIS7_WALMC | I4YAD7 | I4YIS7 | Indoleamine 2,3-dioxygenase. | Tryptophan synthase. | 0.800 |
I4YAK1_WALMC | I4YC16_WALMC | I4YAK1 | I4YC16 | Anthranilate synthase component. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.999 |
I4YAK1_WALMC | I4YCH1_WALMC | I4YAK1 | I4YCH1 | Anthranilate synthase component. | Anthranilate phosphoribosyltransferase. | 0.999 |