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I4Y8R5_WALMC I4Y8R5_WALMC I4Y559_WALMC I4Y559_WALMC I4Y6K8_WALMC I4Y6K8_WALMC I4YJE6_WALMC I4YJE6_WALMC FEN1 FEN1 I4YGZ8_WALMC I4YGZ8_WALMC I4YGR5_WALMC I4YGR5_WALMC I4YFA1_WALMC I4YFA1_WALMC I4YE28_WALMC I4YE28_WALMC I4YC37_WALMC I4YC37_WALMC I4YBG3_WALMC I4YBG3_WALMC I4YBA9_WALMC I4YBA9_WALMC I4YAM3_WALMC I4YAM3_WALMC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I4Y8R5_WALMCDNA polymerase. (1060 aa)
I4Y559_WALMCProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (318 aa)
I4Y6K8_WALMCDNA polymerase alpha, subunit B. (560 aa)
I4YJE6_WALMCDNA polymerase. (1399 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (433 aa)
I4YGZ8_WALMCFAD/NAD(P)-binding domain-containing protein. (503 aa)
I4YGR5_WALMCDNA primase; Belongs to the eukaryotic-type primase small subunit family. (416 aa)
I4YFA1_WALMCReplication factor A protein 3. (111 aa)
I4YE28_WALMCRve-domain-containing protein. (177 aa)
I4YC37_WALMCReplication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (599 aa)
I4YBG3_WALMCUncharacterized protein. (392 aa)
I4YBA9_WALMCUncharacterized protein. (508 aa)
I4YAM3_WALMCDNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (496 aa)
Your Current Organism:
Wallemia mellicola
NCBI taxonomy Id: 671144
Other names: W. mellicola CBS 633.66, Wallemia mellicola CBS 633.66
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