18 items (Wallemia mellicola) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I4Y5B8_WALMC	Pkinase-domain-containing protein. (578 aa)
	I4Y5L3_WALMC	Uncharacterized protein; Belongs to the histone H2B family. (53 aa)
	I4Y6Z0_WALMC	Histone H2B; Belongs to the histone H2B family. (142 aa)
	I4Y7G3_WALMC	Uncharacterized protein. (798 aa)
	I4Y7Z8_WALMC	SMAD/FHA domain-containing protein. (397 aa)
	I4Y9U6_WALMC	14-3-3 protein; Belongs to the 14-3-3 family. (263 aa)
	I4YC33_WALMC	Histone H2B; Belongs to the histone H2B family. (140 aa)
	I4YC37_WALMC	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (599 aa)
	I4YD30_WALMC	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2030 aa)
	hal4	Pkinase-domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
	I4YDJ6_WALMC	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (797 aa)
	I4YDR0_WALMC	Rhodanese-like protein. (553 aa)
	I4YE77_WALMC	ATP-dependent DNA helicase. (1115 aa)
	I4YFP6_WALMC	Ribonuclease H-like protein. (337 aa)
	I4YG30_WALMC	DUF1767 domain-containing protein. (213 aa)
	I4YHB9_WALMC	Uncharacterized protein. (396 aa)
	I4YHE2_WALMC	Pkinase-domain-containing protein. (578 aa)
	I4YJP4_WALMC	SAE2 domain-containing protein. (90 aa)

Your Current Organism:

Wallemia mellicola

NCBI taxonomy Id: 671144
Other names: W. mellicola CBS 633.66, Wallemia mellicola CBS 633.66

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I4Y5B8_WALMC	I4Y7G3_WALMC	I4Y5B8	I4Y7G3	Pkinase-domain-containing protein.	Uncharacterized protein.	0.578
I4Y5B8_WALMC	I4Y7Z8_WALMC	I4Y5B8	I4Y7Z8	Pkinase-domain-containing protein.	SMAD/FHA domain-containing protein.	0.454
I4Y5B8_WALMC	I4YC37_WALMC	I4Y5B8	I4YC37	Pkinase-domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.498
I4Y5B8_WALMC	I4YD30_WALMC	I4Y5B8	I4YD30	Pkinase-domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.962
I4Y5B8_WALMC	I4YDR0_WALMC	I4Y5B8	I4YDR0	Pkinase-domain-containing protein.	Rhodanese-like protein.	0.896
I4Y5B8_WALMC	I4YE77_WALMC	I4Y5B8	I4YE77	Pkinase-domain-containing protein.	ATP-dependent DNA helicase.	0.782
I4Y5B8_WALMC	I4YHB9_WALMC	I4Y5B8	I4YHB9	Pkinase-domain-containing protein.	Uncharacterized protein.	0.454
I4Y5B8_WALMC	I4YHE2_WALMC	I4Y5B8	I4YHE2	Pkinase-domain-containing protein.	Pkinase-domain-containing protein.	0.843
I4Y5B8_WALMC	hal4	I4Y5B8	I4YDE4	Pkinase-domain-containing protein.	Pkinase-domain-containing protein; Belongs to the protein kinase superfamily.	0.842
I4Y7G3_WALMC	I4Y5B8_WALMC	I4Y7G3	I4Y5B8	Uncharacterized protein.	Pkinase-domain-containing protein.	0.578
I4Y7G3_WALMC	I4YC37_WALMC	I4Y7G3	I4YC37	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.829
I4Y7G3_WALMC	I4YD30_WALMC	I4Y7G3	I4YD30	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.976
I4Y7G3_WALMC	I4YDJ6_WALMC	I4Y7G3	I4YDJ6	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.680
I4Y7G3_WALMC	I4YE77_WALMC	I4Y7G3	I4YE77	Uncharacterized protein.	ATP-dependent DNA helicase.	0.867
I4Y7G3_WALMC	I4YFP6_WALMC	I4Y7G3	I4YFP6	Uncharacterized protein.	Ribonuclease H-like protein.	0.673
I4Y7G3_WALMC	I4YG30_WALMC	I4Y7G3	I4YG30	Uncharacterized protein.	DUF1767 domain-containing protein.	0.712
I4Y7G3_WALMC	I4YHE2_WALMC	I4Y7G3	I4YHE2	Uncharacterized protein.	Pkinase-domain-containing protein.	0.719
I4Y7G3_WALMC	I4YJP4_WALMC	I4Y7G3	I4YJP4	Uncharacterized protein.	SAE2 domain-containing protein.	0.699
I4Y7G3_WALMC	hal4	I4Y7G3	I4YDE4	Uncharacterized protein.	Pkinase-domain-containing protein; Belongs to the protein kinase superfamily.	0.719
I4Y7Z8_WALMC	I4Y5B8_WALMC	I4Y7Z8	I4Y5B8	SMAD/FHA domain-containing protein.	Pkinase-domain-containing protein.	0.454