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| | AIL69120.1 | Zn-binding alcohol dehydrogenase. (326 aa) |
| | fadA | 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa) |
| | fadB | Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (723 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (494 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (542 aa) |
| | AIL69435.1 | Acyl dehydratase. (140 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (310 aa) |
| | leuD | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa) |
| | leuC | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (363 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa) |
| | AIL69558.1 | Acetolactate synthase 3 catalytic subunit. (574 aa) |
| | ilvH | Acetolactate synthase 3 regulatory subunit. (164 aa) |
| | AIL69563.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (470 aa) |
| | grcA | Autonomous glycyl radical cofactor GrcA; Acts as a radical domain for damaged PFL and possibly other radical proteins. (125 aa) |
| | AIL69783.1 | Malate synthase; Belongs to the malate synthase family. (545 aa) |
| | AIL69784.1 | Isocitrate lyase. (437 aa) |
| | gltA | Type II citrate synthase; Belongs to the citrate synthase family. (429 aa) |
| | sdhC | Succinate dehydrogenase cytochrome b556 large membrane subunit. (130 aa) |
| | sdhD | Succinate dehydrogenase, hydrophobic anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (114 aa) |
| | sdhA | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa) |
| | sdhB | Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component. (941 aa) |
| | sucB | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (402 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | sucD | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | AIL70186.1 | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (891 aa) |
| | AIL70297.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (482 aa) |
| | AIL70438.1 | acyl-CoA dehydrogenase. (761 aa) |
| | AIL70442.1 | Alcohol dehydrogenase. (415 aa) |
| | sfcA | Malate dehydrogenase (oxaloacetate-decarboxylating); Belongs to the malic enzymes family. (562 aa) |
| | AIL70524.1 | Transcriptional regulator. (231 aa) |
| | prpB | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (298 aa) |
| | AIL70526.1 | Methylcitrate synthase; Belongs to the citrate synthase family. (380 aa) |
| | AIL70527.1 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (866 aa) |
| | AIL70528.1 | 3-methylitaconate isomerase. (408 aa) |
| | AIL70529.1 | PrpE protein. (626 aa) |
| | acyP | Acylphosphatase. (90 aa) |
| | AIL70804.1 | Fe-S oxidoreductase. (1014 aa) |
| | AIL70907.1 | Pyruvate-formate lyase-activating enzyme. (192 aa) |
| | AIL70908.1 | Hypothetical protein. (519 aa) |
| | AIL70925.1 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa) |
| | ackA1 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa) |
| | AIL70976.1 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa) |
| | AIL70993.1 | D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa) |
| | AIL71113.1 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (741 aa) |
| | AIL71130.1 | Formate acetyltransferase. (758 aa) |
| | pflA | Pyruvate formate lyase-activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (246 aa) |
| | fadJ | Multifunctional fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (705 aa) |
| | fadI | 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (435 aa) |
| | AIL71322.1 | acyl-CoA dehydrogenase. (815 aa) |
| | AIL71544.1 | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (865 aa) |
| | AIL71561.1 | Dihydrolipoamide dehydrogenase. (475 aa) |
| | aceF | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (630 aa) |
| | aceE | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (886 aa) |
| | AIL71587.1 | Oxaloacetate decarboxylase subunit beta; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (376 aa) |
| | AIL71588.1 | Oxaloacetate decarboxylase. (594 aa) |
| | oadG | Oxaloacetate decarboxylase subunit gamma; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (85 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (877 aa) |
| | AIL71810.1 | Malic enzyme. (425 aa) |
| | AIL71892.1 | Fumarate reductase flavoprotein subunit. (605 aa) |
| | AIL71893.1 | Fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (252 aa) |
| | frdC | Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (127 aa) |
| | frdD | Fumarate reductase subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (125 aa) |
| | acsA | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa) |
| | AIL72030.1 | Acetolactate synthase 2 catalytic subunit. (548 aa) |
| | ilvM | Acetolactate synthase 2 regulatory subunit. (94 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (312 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (613 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (509 aa) |
| | potE | Putrescine transporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family. (436 aa) |
| | AIL72331.1 | Lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (318 aa) |
| | AIL72493.1 | 3-hydroxyisobutyrate dehydrogenase. (291 aa) |
| | AIL72503.1 | Malate synthase. (190 aa) |
| | AIL72514.1 | Lipoate-protein ligase A. (235 aa) |
| | AIL72562.1 | Glycerol dehydrogenase. (362 aa) |
| | AIL72581.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (790 aa) |
| | AIL72582.1 | PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (277 aa) |
| | AIL72583.1 | Hypothetical protein. (337 aa) |
| | AIL72594.1 | Alcohol dehydrogenase. (382 aa) |
| | ackA2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (954 aa) |
| | AIL72765.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (489 aa) |
| | AIL72829.1 | acyl-CoA synthetase. (892 aa) |
| | AIL73008.1 | acetoacetyl-CoA synthetase. (658 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (364 aa) |
| | pdhB | Pyruvate dehydrogenase E1 component subunit beta. (327 aa) |
| | pdhC | Pyruvate dehydrogenase E2 component. (381 aa) |
| | etfA | Electron transfer flavoprotein subunit alpha. (321 aa) |
| | etfB | Electron transfer flavoprotein subunit beta. (258 aa) |
| | AIL73025.1 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (555 aa) |
| | AIL73036.1 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (302 aa) |
| | AIL73037.1 | enoyl-CoA hydratase/isomerase. (375 aa) |
| | AIL73038.1 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa) |
| | AIL73039.1 | acyl-CoA dehydrogenase. (384 aa) |
| | AIL73040.1 | NAD-dependent aldehyde dehydrogenase. (497 aa) |
| | AIL73041.1 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa) |
| | AIL73044.1 | acyl-CoA dehydrogenase. (389 aa) |
| | AIL73045.1 | acetyl-CoA carboxylase, carboxyltransferase component. (534 aa) |
| | AIL73046.1 | enoyl-CoA hydratase/isomerase. (269 aa) |
| | AIL73047.1 | hydroxymethylglutaryl-CoA lyase. (305 aa) |
| | AIL73190.1 | Poly(3-hydroxyalkanoate) synthetase. (590 aa) |
| | AIL73191.1 | Phasin family protein. (115 aa) |
| | AIL73192.1 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | AIL73193.1 | acetoacetyl-CoA reductase. (246 aa) |
| | AIL73305.1 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa) |
