STRINGSTRING
SMD44_06147 SMD44_06147 SMD44_06123 SMD44_06123 SMD44_06124 SMD44_06124 ilvC ilvC ilvD-2 ilvD-2 poxB poxB SMD44_07157 SMD44_07157 iolD iolD SMD44_03063 SMD44_03063 poxB-2 poxB-2 SMD44_02694 SMD44_02694 ilvD ilvD ilvE-2 ilvE-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMD44_06147Unannotated protein. (362 aa)
SMD44_06123Unannotated protein. (617 aa)
SMD44_06124Unannotated protein. (180 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
ilvD-2Unannotated protein; Belongs to the IlvD/Edd family. (603 aa)
poxBUnannotated protein; Belongs to the TPP enzyme family. (607 aa)
SMD44_07157Unannotated protein. (563 aa)
iolDUnannotated protein; Belongs to the TPP enzyme family. (635 aa)
SMD44_03063Unannotated protein; Belongs to the TPP enzyme family. (561 aa)
poxB-2Unannotated protein; Belongs to the TPP enzyme family. (594 aa)
SMD44_02694Unannotated protein. (329 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (617 aa)
ilvE-2Unannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (311 aa)
Your Current Organism:
Streptomyces alboflavus
NCBI taxonomy Id: 67267
Other names: ATCC 12626, ATCC 23874, Actinomyces alboflavus, BCRC 13664, CBS 613.68, CCRC 13664, CCRC:13664, CIP 104427, DSM 40045, IFO 13196, IMET 42936, ISP 5045, JCM 4615, KCTC 9674, NBRC 13196, NRRL B-2373, NRRL-ISP 5045, S. alboflavus, Streptomyces albiflavus, VKM Ac-972
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.