STRINGSTRING
paaH paaH glpA glpA adhE adhE SMD44_02459 SMD44_02459 SMD44_03393 SMD44_03393 SMD44_06486 SMD44_06486 SMD44_02977 SMD44_02977 panE-4 panE-4 SMD44_00094 SMD44_00094 SMD44_02022 SMD44_02022 SMD44_02046 SMD44_02046 ldhA ldhA SMD44_06120 SMD44_06120 ilvC ilvC serA-2 serA-2 leuB leuB SMD44_04020 SMD44_04020 lhgO lhgO yahK yahK SMD44_01177 SMD44_01177 hisD hisD SMD44_05846 SMD44_05846 guaB-4 guaB-4 SMD44_00104 SMD44_00104 SMD44_05300 SMD44_05300 glpA-3 glpA-3 SMD44_05291 SMD44_05291 guaB-3 guaB-3 guaB-2 guaB-2 tdh tdh iolG-3 iolG-3 SMD44_07494 SMD44_07494 glpA-2 glpA-2 paaH-5 paaH-5 SMD44_05899 SMD44_05899 SMD44_07628 SMD44_07628 paaH-4 paaH-4 SMD44_04423 SMD44_04423 SMD44_05361 SMD44_05361 mdh mdh araM araM fadJ fadJ zwf zwf mviM mviM aroE aroE guaB guaB ribD ribD GCA_000716675_03643 GCA_000716675_03643 iolG-2 iolG-2 paaH-3 paaH-3 SMD44_02782 SMD44_02782 SMD44_02780 SMD44_02780 dxr dxr gpsA gpsA ttuC ttuC SMD44_02533 SMD44_02533 SMD44_02628 SMD44_02628 iolG iolG panE-3 panE-3 SMD44_03046 SMD44_03046 panE-2 panE-2 SMD44_07133 SMD44_07133 SMD44_07180 SMD44_07180 SMD44_07181 SMD44_07181 lcdH lcdH SMD44_07204 SMD44_07204 murB murB serA serA paaH-2 paaH-2 SMD44_08062 SMD44_08062 algD algD SMD44_04332 SMD44_04332 SMD44_06659 SMD44_06659 SMD44_06629 SMD44_06629 panE panE SMD44_03169 SMD44_03169 SMD44_03272 SMD44_03272 SMD44_01136 SMD44_01136 SMD44_01119 SMD44_01119 SMD44_00810 SMD44_00810 SMD44_00204 SMD44_00204 melA melA slcC slcC SMD44_08643 SMD44_08643 SMD44_08480 SMD44_08480 SMD44_01631 SMD44_01631 SMD44_01635 SMD44_01635
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
paaHUnannotated protein. (286 aa)
glpAUnannotated protein. (539 aa)
adhEUnannotated protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (896 aa)
SMD44_02459Unannotated protein. (365 aa)
SMD44_03393Unannotated protein. (447 aa)
SMD44_06486Unannotated protein. (371 aa)
SMD44_02977Unannotated protein. (421 aa)
panE-4Unannotated protein. (333 aa)
SMD44_00094Unannotated protein. (388 aa)
SMD44_02022Unannotated protein. (373 aa)
SMD44_02046Unannotated protein. (329 aa)
ldhAUnannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa)
SMD44_06120Unannotated protein. (332 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
serA-2Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (534 aa)
leuBUnannotated protein. (346 aa)
SMD44_04020Unannotated protein. (314 aa)
lhgOUnannotated protein. (401 aa)
yahKUnannotated protein. (350 aa)
SMD44_01177Unannotated protein. (309 aa)
hisDUnannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa)
SMD44_05846Unannotated protein. (404 aa)
guaB-4Unannotated protein. (391 aa)
SMD44_00104Unannotated protein. (228 aa)
SMD44_05300Unannotated protein. (608 aa)
glpA-3Unannotated protein. (568 aa)
SMD44_05291Unannotated protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (417 aa)
guaB-3Unannotated protein. (374 aa)
guaB-2Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (502 aa)
tdhUnannotated protein. (342 aa)
iolG-3Unannotated protein. (356 aa)
SMD44_07494Unannotated protein. (338 aa)
glpA-2Unannotated protein. (525 aa)
paaH-5Unannotated protein. (282 aa)
SMD44_05899Unannotated protein. (429 aa)
SMD44_07628Unannotated protein; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
paaH-4Unannotated protein. (504 aa)
SMD44_04423Unannotated protein. (344 aa)
SMD44_05361Unannotated protein. (511 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
araMUnannotated protein. (354 aa)
fadJUnannotated protein. (730 aa)
zwfUnannotated protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
mviMUnannotated protein. (301 aa)
aroEUnannotated protein; Belongs to the shikimate dehydrogenase family. (276 aa)
guaBUnannotated protein. (480 aa)
ribDUnannotated protein. (448 aa)
GCA_000716675_03643Unannotated protein. (335 aa)
iolG-2Unannotated protein. (346 aa)
paaH-3Unannotated protein. (593 aa)
SMD44_02782Unannotated protein. (526 aa)
SMD44_02780Unannotated protein. (338 aa)
dxrUnannotated protein. (432 aa)
gpsAUnannotated protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (336 aa)
ttuCUnannotated protein. (355 aa)
SMD44_02533Unannotated protein. (290 aa)
SMD44_02628Unannotated protein. (335 aa)
iolGUnannotated protein; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (337 aa)
panE-3Unannotated protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (326 aa)
SMD44_03046Unannotated protein. (383 aa)
panE-2Unannotated protein. (326 aa)
SMD44_07133Unannotated protein. (460 aa)
SMD44_07180Unannotated protein. (340 aa)
SMD44_07181Unannotated protein. (351 aa)
lcdHUnannotated protein; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (327 aa)
SMD44_07204Unannotated protein. (446 aa)
murBUnannotated protein; Cell wall formation. (351 aa)
serAUnannotated protein. (360 aa)
paaH-2Unannotated protein. (289 aa)
SMD44_08062Unannotated protein. (736 aa)
algDUnannotated protein. (438 aa)
SMD44_04332Unannotated protein. (294 aa)
SMD44_06659Unannotated protein. (270 aa)
SMD44_06629Unannotated protein. (710 aa)
panEUnannotated protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (334 aa)
SMD44_03169Unannotated protein. (360 aa)
SMD44_03272Unannotated protein. (476 aa)
SMD44_01136Unannotated protein. (342 aa)
SMD44_01119Unannotated protein. (417 aa)
SMD44_00810Unannotated protein. (378 aa)
SMD44_00204Unannotated protein. (538 aa)
melAUnannotated protein. (437 aa)
slcCUnannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
SMD44_08643Unannotated protein. (377 aa)
SMD44_08480Unannotated protein. (361 aa)
SMD44_01631Unannotated protein; Belongs to the monomeric-type IDH family. (739 aa)
SMD44_01635Unannotated protein. (329 aa)
Your Current Organism:
Streptomyces alboflavus
NCBI taxonomy Id: 67267
Other names: ATCC 12626, ATCC 23874, Actinomyces alboflavus, BCRC 13664, CBS 613.68, CCRC 13664, CCRC:13664, CIP 104427, DSM 40045, IFO 13196, IMET 42936, ISP 5045, JCM 4615, KCTC 9674, NBRC 13196, NRRL B-2373, NRRL-ISP 5045, S. alboflavus, Streptomyces albiflavus, VKM Ac-972
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