STRINGSTRING
SMD44_04429 SMD44_04429 iscS iscS SMD44_03930 SMD44_03930 lysA lysA thrC-2 thrC-2 glyA-2 glyA-2 thrC-3 thrC-3 SMD44_08937 SMD44_08937 SMD44_02694 SMD44_02694 serC serC SMD44_04844 SMD44_04844 SMD44_07589 SMD44_07589 SMD44_07588 SMD44_07588 SMD44_07587 SMD44_07587 SMD44_07585 SMD44_07585 SMD44_07584 SMD44_07584 SMD44_07582 SMD44_07582 SMD44_07581 SMD44_07581 GCA_000716675_05216 GCA_000716675_05216 SMD44_07521 SMD44_07521 GCA_000716675_05257 GCA_000716675_05257 SMD44_07514 SMD44_07514 SMD44_07510 SMD44_07510 SMD44_07474 SMD44_07474 SMD44_07463 SMD44_07463 SMD44_07462 SMD44_07462 SMD44_07461 SMD44_07461 argD-2 argD-2 SMD44_07428 SMD44_07428 kbl kbl alr alr SMD44_05283 SMD44_05283 SMD44_05320 SMD44_05320 SMD44_00097 SMD44_00097 SMD44_08818 SMD44_08818 kynU kynU SMD44_04283 SMD44_04283 SMD44_04305 SMD44_04305 hemL hemL GCA_000716675_01932 GCA_000716675_01932 GCA_000716675_01934 GCA_000716675_01934 poxB poxB SMD44_05207 SMD44_05207 korB korB SMD44_08555 SMD44_08555 SMD44_07157 SMD44_07157 thrC thrC iolD iolD SMD44_03063 SMD44_03063 ddc ddc SMD44_08510 SMD44_08510 SMD44_08303 SMD44_08303 SMD44_08298 SMD44_08298 argD argD metH metH SMD44_06435 SMD44_06435 SMD44_06427 SMD44_06427 SMD44_06123 SMD44_06123 alaA-2 alaA-2 bioF bioF bioA bioA lysA-3 lysA-3 SMD44_02014 SMD44_02014 SMD44_06718 SMD44_06718 iscS-2 iscS-2 thrC-4 thrC-4 SMD44_04662 SMD44_04662 patB patB dapC dapC lysA-2 lysA-2 SMD44_06032 SMD44_06032 glyA-3 glyA-3 SMD44_05697 SMD44_05697 SMD44_05966 SMD44_05966 SMD44_06010 SMD44_06010 hisC-3 hisC-3 SMD44_02283 SMD44_02283 SMD44_04949 SMD44_04949 hemL-2 hemL-2 SMD44_04993 SMD44_04993 SMD44_05553 SMD44_05553 metB metB ddc-2 ddc-2 GCA_000716675_06558 GCA_000716675_06558 dxs dxs SMD44_06554 SMD44_06554 SMD44_01056 SMD44_01056 SMD44_00833 SMD44_00833 SMD44_00395 SMD44_00395 GCA_000716675_00633 GCA_000716675_00633 SMD44_00479 SMD44_00479 SMD44_00480 SMD44_00480 SMD44_08727 SMD44_08727 SMD44_08724 SMD44_08724 SMD44_08701 SMD44_08701 SMD44_05408 SMD44_05408 SMD44_07323 SMD44_07323 dxs-2 dxs-2 sufS sufS SMD44_01265 SMD44_01265 SMD44_01266 SMD44_01266 gcvP gcvP GCA_000716675_03738 GCA_000716675_03738 SMD44_01444 SMD44_01444 puuE puuE SMD44_07074 SMD44_07074 gabT gabT SMD44_06271 SMD44_06271 dhbF dhbF thiB thiB poxB-2 poxB-2 gcl gcl alaA alaA hisC-2 hisC-2 GCA_000716675_08250 GCA_000716675_08250 SMD44_07592 SMD44_07592 SMD44_07593 SMD44_07593 GCA_000716675_08080 GCA_000716675_08080 SMD44_07594 SMD44_07594 GCA_000716675_08078 GCA_000716675_08078 GCA_000716675_08077 GCA_000716675_08077 SMD44_07597 SMD44_07597 SMD44_07606 SMD44_07606 SMD44_05857 SMD44_05857 SMD44_04169 SMD44_04169 hisC hisC glyA glyA SMD44_04408 SMD44_04408
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMD44_04429Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
iscSUnannotated protein; Belongs to the sulfur carrier protein TusA family. (417 aa)
SMD44_03930Unannotated protein. (378 aa)
lysAUnannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa)
thrC-2Unannotated protein; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa)
glyA-2Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (432 aa)
thrC-3Unannotated protein; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (360 aa)
SMD44_08937Unannotated protein. (6258 aa)
SMD44_02694Unannotated protein. (329 aa)
serCUnannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
SMD44_04844Unannotated protein; Belongs to the group II decarboxylase family. (470 aa)
SMD44_07589Unannotated protein. (920 aa)
SMD44_07588Unannotated protein. (1856 aa)
SMD44_07587Unannotated protein. (1948 aa)
SMD44_07585Unannotated protein. (813 aa)
SMD44_07584Unannotated protein. (2446 aa)
SMD44_07582Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (739 aa)
SMD44_07581Unannotated protein. (1062 aa)
GCA_000716675_05216Unannotated protein. (293 aa)
SMD44_07521Unannotated protein. (2233 aa)
GCA_000716675_05257Unannotated protein. (644 aa)
SMD44_07514Unannotated protein. (3353 aa)
SMD44_07510Unannotated protein. (2066 aa)
SMD44_07474Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (981 aa)
SMD44_07463Unannotated protein. (645 aa)
SMD44_07462Unannotated protein; Belongs to the ATP-dependent AMP-binding enzyme family. (547 aa)
SMD44_07461Unannotated protein. (2671 aa)
argD-2Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (415 aa)
SMD44_07428Unannotated protein. (1295 aa)
kblUnannotated protein; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (400 aa)
alrUnannotated protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (386 aa)
SMD44_05283Unannotated protein. (222 aa)
SMD44_05320Unannotated protein. (138 aa)
SMD44_00097Unannotated protein. (3631 aa)
SMD44_08818Unannotated protein. (458 aa)
kynUUnannotated protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (434 aa)
SMD44_04283Unannotated protein. (410 aa)
SMD44_04305Unannotated protein. (343 aa)
hemLUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa)
GCA_000716675_01932Unannotated protein. (1129 aa)
GCA_000716675_01934Unannotated protein. (372 aa)
poxBUnannotated protein; Belongs to the TPP enzyme family. (607 aa)
SMD44_05207Unannotated protein. (450 aa)
korBUnannotated protein. (360 aa)
SMD44_08555Unannotated protein. (404 aa)
SMD44_07157Unannotated protein. (563 aa)
thrCUnannotated protein. (408 aa)
iolDUnannotated protein; Belongs to the TPP enzyme family. (635 aa)
SMD44_03063Unannotated protein; Belongs to the TPP enzyme family. (561 aa)
ddcUnannotated protein. (480 aa)
SMD44_08510Unannotated protein. (374 aa)
SMD44_08303Unannotated protein. (584 aa)
SMD44_08298Unannotated protein. (424 aa)
argDUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (408 aa)
metHUnannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1182 aa)
SMD44_06435Unannotated protein; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (963 aa)
SMD44_06427Unannotated protein. (638 aa)
SMD44_06123Unannotated protein. (617 aa)
alaA-2Unannotated protein. (403 aa)
bioFUnannotated protein. (378 aa)
bioAUnannotated protein; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (439 aa)
lysA-3Unannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (456 aa)
SMD44_02014Unannotated protein; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
SMD44_06718Unannotated protein. (486 aa)
iscS-2Unannotated protein. (392 aa)
thrC-4Unannotated protein. (432 aa)
SMD44_04662Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
patBUnannotated protein. (542 aa)
dapCUnannotated protein. (417 aa)
lysA-2Unannotated protein. (475 aa)
SMD44_06032Unannotated protein. (876 aa)
glyA-3Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
SMD44_05697Unannotated protein. (384 aa)
SMD44_05966Unannotated protein. (566 aa)
SMD44_06010Unannotated protein. (406 aa)
hisC-3Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (379 aa)
SMD44_02283Unannotated protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (239 aa)
SMD44_04949Unannotated protein. (400 aa)
hemL-2Unannotated protein. (451 aa)
SMD44_04993Unannotated protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (310 aa)
SMD44_05553Unannotated protein. (420 aa)
metBUnannotated protein. (384 aa)
ddc-2Unannotated protein. (463 aa)
GCA_000716675_06558Unannotated protein. (393 aa)
dxsUnannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (659 aa)
SMD44_06554Unannotated protein. (920 aa)
SMD44_01056Unannotated protein. (322 aa)
SMD44_00833Unannotated protein. (277 aa)
SMD44_00395Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
GCA_000716675_00633Unannotated protein. (753 aa)
SMD44_00479Unannotated protein. (3740 aa)
SMD44_00480Unannotated protein. (4390 aa)
SMD44_08727Unannotated protein. (682 aa)
SMD44_08724Unannotated protein. (934 aa)
SMD44_08701Unannotated protein. (585 aa)
SMD44_05408Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (400 aa)
SMD44_07323Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
dxs-2Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (666 aa)
sufSUnannotated protein; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
SMD44_01265Unannotated protein. (617 aa)
SMD44_01266Unannotated protein. (744 aa)
gcvPUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (962 aa)
GCA_000716675_03738Unannotated protein. (404 aa)
SMD44_01444Unannotated protein. (501 aa)
puuEUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
SMD44_07074Unannotated protein. (415 aa)
gabTUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
SMD44_06271Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)
dhbFUnannotated protein. (2444 aa)
thiBUnannotated protein. (360 aa)
poxB-2Unannotated protein; Belongs to the TPP enzyme family. (594 aa)
gclUnannotated protein; Belongs to the TPP enzyme family. (595 aa)
alaAUnannotated protein. (403 aa)
hisC-2Unannotated protein; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (365 aa)
GCA_000716675_08250Unannotated protein. (612 aa)
SMD44_07592Unannotated protein. (1197 aa)
SMD44_07593Unannotated protein. (798 aa)
GCA_000716675_08080Unannotated protein. (609 aa)
SMD44_07594Unannotated protein. (1229 aa)
GCA_000716675_08078Unannotated protein. (573 aa)
GCA_000716675_08077Unannotated protein. (676 aa)
SMD44_07597Unannotated protein. (3988 aa)
SMD44_07606Unannotated protein. (3633 aa)
SMD44_05857Unannotated protein. (1270 aa)
SMD44_04169Unannotated protein. (276 aa)
hisCUnannotated protein; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
glyAUnannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa)
SMD44_04408Unannotated protein. (384 aa)
Your Current Organism:
Streptomyces alboflavus
NCBI taxonomy Id: 67267
Other names: ATCC 12626, ATCC 23874, Actinomyces alboflavus, BCRC 13664, CBS 613.68, CCRC 13664, CCRC:13664, CIP 104427, DSM 40045, IFO 13196, IMET 42936, ISP 5045, JCM 4615, KCTC 9674, NBRC 13196, NRRL B-2373, NRRL-ISP 5045, S. alboflavus, Streptomyces albiflavus, VKM Ac-972
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