STRINGSTRING
rnd rnd dnaE2 dnaE2 SMD44_01733 SMD44_01733 SMD44_01707 SMD44_01707 SMD44_01676 SMD44_01676 SMD44_03214 SMD44_03214 SMD44_03213 SMD44_03213 rph rph SMD44_03184 SMD44_03184 vsr vsr GCA_000716675_01329 GCA_000716675_01329 GCA_000716675_01330 GCA_000716675_01330 GCA_000716675_01393 GCA_000716675_01393 vapC vapC SMD44_04272 SMD44_04272 SMD44_04331 SMD44_04331 SMD44_07953 SMD44_07953 uvrA uvrA SMD44_07858 SMD44_07858 SMD44_04708 SMD44_04708 SMD44_04783 SMD44_04783 GCA_000716675_02241 GCA_000716675_02241 recD recD orn orn SMD44_00538 SMD44_00538 rnc rnc SMD44_06249 SMD44_06249 ybeY ybeY rnz rnz SMD44_02839 SMD44_02839 SMD44_06953 SMD44_06953 SMD44_06882 SMD44_06882 SMD44_01499 SMD44_01499 SMD44_01528 SMD44_01528 ruvX ruvX ruvC ruvC SMD44_01576 SMD44_01576 sbcD sbcD SMD44_02056 SMD44_02056 SMD44_02059 SMD44_02059 uvrC uvrC uvrA-2 uvrA-2 uvrB uvrB SMD44_02150 SMD44_02150 SMD44_07242 SMD44_07242 SMD44_07259 SMD44_07259 nfi nfi SMD44_07699 SMD44_07699 mutM-2 mutM-2 SMD44_07667 SMD44_07667 GCA_000716675_04587 GCA_000716675_04587 GCA_000716675_04635 GCA_000716675_04635 SMD44_05895 SMD44_05895 nucS nucS GCA_000716675_04774 GCA_000716675_04774 SMD44_03661 SMD44_03661 SMD44_03667 SMD44_03667 GCA_000716675_04840 GCA_000716675_04840 SMD44_01926 SMD44_01926 SMD44_01970 SMD44_01970 SMD44_02698 SMD44_02698 vapC-2 vapC-2 SMD44_00096 SMD44_00096 SMD44_03542 SMD44_03542 tatD tatD uvrD-3 uvrD-3 SMD44_05750 SMD44_05750 SMD44_02262 SMD44_02262 SMD44_02264 SMD44_02264 rne rne SMD44_02886 SMD44_02886 GCA_000716675_06493 GCA_000716675_06493 polA polA rnhB rnhB GCA_000716675_06852 GCA_000716675_06852 GCA_000716675_06866 GCA_000716675_06866 GCA_000716675_06870 GCA_000716675_06870 GCA_000716675_06872 GCA_000716675_06872 nfo nfo SMD44_06709 SMD44_06709 xseB xseB xseA xseA SMD44_04532 SMD44_04532 rnj rnj SMD44_05723 SMD44_05723 SMD44_05726 SMD44_05726 SMD44_02971 SMD44_02971 SMD44_05648 SMD44_05648 SMD44_02523 SMD44_02523 SMD44_02526 SMD44_02526 GCA_000716675_07688 GCA_000716675_07688 SMD44_02505 SMD44_02505 SMD44_05890 SMD44_05890 GCA_000716675_07948 GCA_000716675_07948 GCA_000716675_08164 GCA_000716675_08164 SMD44_01392 SMD44_01392 SMD44_04821 SMD44_04821 SMD44_04825 SMD44_04825
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rndUnannotated protein. (384 aa)
dnaE2Unannotated protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1034 aa)
SMD44_01733Unannotated protein. (937 aa)
SMD44_01707Unannotated protein. (293 aa)
SMD44_01676Unannotated protein. (304 aa)
SMD44_03214Unannotated protein. (91 aa)
SMD44_03213Unannotated protein. (251 aa)
rphUnannotated protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (243 aa)
SMD44_03184Unannotated protein. (256 aa)
vsrUnannotated protein. (158 aa)
GCA_000716675_01329Unannotated protein. (322 aa)
GCA_000716675_01330Unannotated protein. (295 aa)
GCA_000716675_01393Unannotated protein. (598 aa)
vapCUnannotated protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (147 aa)
SMD44_04272Unannotated protein. (534 aa)
SMD44_04331Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (376 aa)
SMD44_07953Unannotated protein. (301 aa)
uvrAUnannotated protein. (793 aa)
SMD44_07858Unannotated protein. (381 aa)
SMD44_04708Unannotated protein. (241 aa)
SMD44_04783Unannotated protein. (401 aa)
GCA_000716675_02241Unannotated protein. (369 aa)
recDUnannotated protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (735 aa)
ornUnannotated protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (200 aa)
SMD44_00538Unannotated protein. (754 aa)
rncUnannotated protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (261 aa)
SMD44_06249Unannotated protein; Belongs to the UPF0102 family. (120 aa)
ybeYUnannotated protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (165 aa)
rnzUnannotated protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (295 aa)
SMD44_02839Unannotated protein. (272 aa)
SMD44_06953Unannotated protein. (259 aa)
SMD44_06882Unannotated protein. (141 aa)
SMD44_01499Unannotated protein. (150 aa)
SMD44_01528Unannotated protein. (162 aa)
ruvXUnannotated protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (158 aa)
ruvCUnannotated protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (215 aa)
SMD44_01576Unannotated protein. (241 aa)
sbcDUnannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (397 aa)
SMD44_02056Unannotated protein. (385 aa)
SMD44_02059Unannotated protein. (612 aa)
uvrCUnannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (731 aa)
uvrA-2Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1028 aa)
uvrBUnannotated protein. (722 aa)
SMD44_02150Unannotated protein. (321 aa)
SMD44_07242Unannotated protein. (339 aa)
SMD44_07259Unannotated protein. (778 aa)
nfiUnannotated protein; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (236 aa)
SMD44_07699Unannotated protein. (164 aa)
mutM-2Unannotated protein; Belongs to the FPG family. (286 aa)
SMD44_07667Unannotated protein. (799 aa)
GCA_000716675_04587Unannotated protein. (206 aa)
GCA_000716675_04635Unannotated protein. (230 aa)
SMD44_05895Unannotated protein. (197 aa)
nucSUnannotated protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (223 aa)
GCA_000716675_04774Unannotated protein. (118 aa)
SMD44_03661Unannotated protein. (505 aa)
SMD44_03667Unannotated protein. (294 aa)
GCA_000716675_04840Unannotated protein. (134 aa)
SMD44_01926Unannotated protein. (168 aa)
SMD44_01970Unannotated protein. (372 aa)
SMD44_02698Unannotated protein. (277 aa)
vapC-2Unannotated protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (135 aa)
SMD44_00096Unannotated protein. (237 aa)
SMD44_03542Unannotated protein. (263 aa)
tatDUnannotated protein. (248 aa)
uvrD-3Unannotated protein; Belongs to the helicase family. UvrD subfamily. (1246 aa)
SMD44_05750Unannotated protein; Belongs to the helicase family. UvrD subfamily. (607 aa)
SMD44_02262Unannotated protein. (404 aa)
SMD44_02264Unannotated protein. (1179 aa)
rneUnannotated protein. (1445 aa)
SMD44_02886Unannotated protein. (689 aa)
GCA_000716675_06493Unannotated protein. (261 aa)
polAUnannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (921 aa)
rnhBUnannotated protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (233 aa)
GCA_000716675_06852Unannotated protein. (198 aa)
GCA_000716675_06866Unannotated protein. (201 aa)
GCA_000716675_06870Unannotated protein. (241 aa)
GCA_000716675_06872Unannotated protein. (352 aa)
nfoUnannotated protein; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (299 aa)
SMD44_06709Unannotated protein. (235 aa)
xseBUnannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (84 aa)
xseAUnannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (403 aa)
SMD44_04532Unannotated protein. (342 aa)
rnjUnannotated protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (567 aa)
SMD44_05723Unannotated protein. (291 aa)
SMD44_05726Unannotated protein. (310 aa)
SMD44_02971Unannotated protein. (178 aa)
SMD44_05648Unannotated protein. (84 aa)
SMD44_02523Unannotated protein. (480 aa)
SMD44_02526Unannotated protein. (465 aa)
GCA_000716675_07688Unannotated protein. (141 aa)
SMD44_02505Unannotated protein. (175 aa)
SMD44_05890Unannotated protein. (299 aa)
GCA_000716675_07948Unannotated protein. (154 aa)
GCA_000716675_08164Unannotated protein. (166 aa)
SMD44_01392Unannotated protein. (157 aa)
SMD44_04821Unannotated protein. (553 aa)
SMD44_04825Unannotated protein. (394 aa)
Your Current Organism:
Streptomyces alboflavus
NCBI taxonomy Id: 67267
Other names: ATCC 12626, ATCC 23874, Actinomyces alboflavus, BCRC 13664, CBS 613.68, CCRC 13664, CCRC:13664, CIP 104427, DSM 40045, IFO 13196, IMET 42936, ISP 5045, JCM 4615, KCTC 9674, NBRC 13196, NRRL B-2373, NRRL-ISP 5045, S. alboflavus, Streptomyces albiflavus, VKM Ac-972
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.