STRINGSTRING
EQU24_14750 EQU24_14750 glcF glcF glcE glcE EQU24_13600 EQU24_13600 lpdA lpdA EQU24_11515 EQU24_11515 EQU24_11510 EQU24_11510 gcvH gcvH EQU24_08475 EQU24_08475 acs acs EQU24_07185 EQU24_07185 EQU24_06520 EQU24_06520 eda eda gltA gltA lpdA-3 lpdA-3 acnB acnB EQU24_06010 EQU24_06010 EQU24_04860 EQU24_04860 sucD sucD sucC sucC EQU24_04630 EQU24_04630 EQU24_04625 EQU24_04625 EQU24_04580 EQU24_04580 mdh mdh EQU24_04565 EQU24_04565 glyA glyA EQU24_01475 EQU24_01475 EQU24_01470 EQU24_01470 EQU24_01465 EQU24_01465 EQU24_01455 EQU24_01455 acnA acnA EQU24_17310 EQU24_17310 gcvP gcvP gcvT gcvT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EQU24_14750Unannotated protein; Serves to protect cells from the toxic effects of hydrogen peroxide. (706 aa)
glcFUnannotated protein. (422 aa)
glcEUnannotated protein. (356 aa)
EQU24_13600Unannotated protein. (499 aa)
lpdAUnannotated protein. (478 aa)
EQU24_11515Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (924 aa)
EQU24_11510Unannotated protein. (568 aa)
gcvHUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
EQU24_08475Unannotated protein. (409 aa)
acsUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
EQU24_07185Unannotated protein. (469 aa)
EQU24_06520Unannotated protein; Belongs to the hyi family. (262 aa)
edaUnannotated protein. (216 aa)
gltAUnannotated protein; Belongs to the citrate synthase family. (432 aa)
lpdA-3Unannotated protein. (479 aa)
acnBUnannotated protein; Belongs to the aconitase/IPM isomerase family. (856 aa)
EQU24_06010Unannotated protein; Belongs to the citrate synthase family. (435 aa)
EQU24_04860Unannotated protein. (215 aa)
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (296 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa)
EQU24_04630Unannotated protein; Belongs to the HpcH/HpaI aldolase family. (316 aa)
EQU24_04625Unannotated protein. (387 aa)
EQU24_04580Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
EQU24_04565Unannotated protein. (455 aa)
glyAUnannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
EQU24_01475Unannotated protein. (158 aa)
EQU24_01470Unannotated protein. (517 aa)
EQU24_01465Unannotated protein. (951 aa)
EQU24_01455Unannotated protein. (70 aa)
acnAUnannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (899 aa)
EQU24_17310Unannotated protein. (417 aa)
gcvPUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (964 aa)
gcvTUnannotated protein. (374 aa)
Your Current Organism:
Methylomicrobium buryatense
NCBI taxonomy Id: 675511
Other names: M. buryatense 5G, Methylomicrobium buryatense 5G, Methylomicrobium buryatense str. 5G, Methylomicrobium buryatense strain 5G
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.