STRINGSTRING
ARD39041.1 ARD39041.1 ARD38099.1 ARD38099.1 B6E78_02325 B6E78_02325 ARD38396.1 ARD38396.1 ARD38397.1 ARD38397.1 fumC fumC ARD38599.1 ARD38599.1 ARD38600.1 ARD38600.1 B6E78_03805 B6E78_03805 ARD38628.1 ARD38628.1 ARD38752.1 ARD38752.1 ARD38753.1 ARD38753.1 ARD38754.1 ARD38754.1 ARD38817.1 ARD38817.1 ARD38818.1 ARD38818.1 ARD38884.1 ARD38884.1 ARD38885.1 ARD38885.1 ARD38886.1 ARD38886.1 ARD38887.1 ARD38887.1 B6E78_05325 B6E78_05325 nuoN nuoN ARD38891.1 ARD38891.1 ARD38892.1 ARD38892.1 nuoK nuoK nuoI nuoI nuoH nuoH ARD38897.1 ARD38897.1 ARD38899.1 ARD38899.1 nuoC nuoC ARD39039.1 ARD39039.1 ARD39040.1 ARD39040.1 sucD sucD sucC sucC ARD39045.1 ARD39045.1 sdhB sdhB ARD39047.1 ARD39047.1 ARD39048.1 ARD39048.1 ARD39049.1 ARD39049.1 ARD39051.1 ARD39051.1 ARD39195.1 ARD39195.1 ARD39238.1 ARD39238.1 ARD39239.1 ARD39239.1 nrfA nrfA ARD39320.1 ARD39320.1 hycD hycD hycE hycE ARD39323.1 ARD39323.1 ARD39439.1 ARD39439.1 ARD39440.1 ARD39440.1 ARD39445.1 ARD39445.1 ARD39446.1 ARD39446.1 ARD39447.1 ARD39447.1 ARD39483.1 ARD39483.1 ARD39641.1 ARD39641.1 ARD39642.1 ARD39642.1 ARD39643.1 ARD39643.1 ARD39702.1 ARD39702.1 ARD39703.1 ARD39703.1 ARD39704.1 ARD39704.1 ARD39705.1 ARD39705.1 ppc ppc ubiE ubiE ARD40099.1 ARD40099.1 ARD40100.1 ARD40100.1 ARD40114.1 ARD40114.1 ARD40120.1 ARD40120.1 frdC frdC ARD40125.1 ARD40125.1 ARD40126.1 ARD40126.1 mdh mdh ARD40939.1 ARD40939.1 ARD40415.1 ARD40415.1 B6E78_15130 B6E78_15130 B6E78_15960 B6E78_15960 ARD40676.1 ARD40676.1 dld dld napB napB ARD40752.1 ARD40752.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARD39041.1Cytochrome bd-I ubiquinol oxidase subunit I; Part of the aerobic respiratory chain; catalyzes the ubiquinol to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
ARD38099.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
B6E78_02325Hypothetical protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (758 aa)
ARD38396.1Thiosulfate reductase electron transport protein PhsB; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
ARD38397.1Thiosulfate reductase cytochrome B subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa)
ARD38599.1Cytochrome o ubiquinol oxidase subunit III; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
ARD38600.1Cytochrome o ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family. (663 aa)
B6E78_03805Protein deglycase HchA; Frameshifted; internal stop; incomplete; partial on complete genome; missing start and stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (58 aa)
ARD38628.1Isocitrate dehydrogenase (NADP(+)); Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
ARD38752.1Dimethylsulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
ARD38753.1Dimethylsulfoxide reductase, chain B; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
ARD38754.1Dimethyl sulfoxide reductase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (815 aa)
ARD38817.1Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TorC/TorY family. (389 aa)
ARD38818.1trimethylamine-N-oxide reductase TorA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (830 aa)
ARD38884.1Hydrogenase 2 large subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
ARD38885.1Ni/Fe-hydrogenase cytochrome b subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
ARD38886.1Hydrogenase 2 protein HybA; Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
ARD38887.1Hydrogenase 2 small subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
B6E78_05325Sugar glycosyltransferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
nuoNNADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa)
ARD38891.1NADH-quinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
ARD38892.1NADH-quinone oxidoreductase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (614 aa)
nuoKNADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
nuoINADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoHNADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa)
ARD38897.1NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (911 aa)
ARD38899.1NADH-quinone oxidoreductase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
nuoCNADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. (598 aa)
ARD39039.1Cyd operon protein YbgT; Derived by automated computational analysis using gene prediction method: Protein Homology. (36 aa)
ARD39040.1Cytochrome d ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
ARD39045.12-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (935 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
ARD39047.1Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
ARD39048.1Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
ARD39049.1Succinate dehydrogenase cytochrome b556 large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
ARD39051.1Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (427 aa)
ARD39195.1Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
ARD39238.1Cytochrome c nitrite reductase Fe-S protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
ARD39239.1Cytochrome C nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
nrfAAmmonia-forming cytochrome c nitrite reductase subunit c552; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (482 aa)
ARD39320.1Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa)
hycDHydrogenase 3 membrane subunit; Formate hydrogenlyase subunit 4; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
hycEHydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
ARD39323.1Electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
ARD39439.1Cytochrome d ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
ARD39440.1Cytochrome d terminal oxidase subunit 1; Part of the aerobic respiratory chain; catalyzes the ubiquinol to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
ARD39445.1Ni/Fe-hydrogenase, b-type cytochrome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
ARD39446.1Hydrogenase 2 large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (597 aa)
ARD39447.1[Ni/Fe] hydrogenase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
ARD39483.1Sn-glycerol-3-phosphate dehydrogenase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
ARD39641.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
ARD39642.1Thiosulfate reductase cytochrome B subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
ARD39643.1Cytochrome C; Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process; Belongs to the multiheme cytochrome c family. (648 aa)
ARD39702.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
ARD39703.1Formate dehydrogenase-N subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (804 aa)
ARD39704.1Formate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (317 aa)
ARD39705.1Formate dehydrogenase cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (877 aa)
ubiEUbiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa)
ARD40099.1trimethylamine-N-oxide reductase TorA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (848 aa)
ARD40100.1Pentaheme c-type cytochrome TorC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TorC/TorY family. (391 aa)
ARD40114.1Aspartate ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
ARD40120.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
frdCFumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (132 aa)
ARD40125.1Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
ARD40126.1Fumarate reductase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
ARD40939.1Nickel-dependent hydrogenase cytochrome b-type subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
ARD40415.1Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. (874 aa)
B6E78_15130IS256 family transposase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
B6E78_15960IS481 family transposase; Incomplete; partial on complete genome; missing start and stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
ARD40676.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (533 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (574 aa)
napBNitrate reductase; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (150 aa)
ARD40752.1Cytochrome c-type protein NapC; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
Your Current Organism:
Edwardsiella ictaluri
NCBI taxonomy Id: 67780
Other names: ATCC 33202, CCUG 18764, CIP 81.96, DSM 13697, E. ictaluri, JCM 16934, NCTC 12122, SECFDL GA 77-52
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