(16 nodes) Glutathione metabolism network (Edwardsiella ictaluri)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARD38048.1	Derived by automated computational analysis using gene prediction method: Protein Homology. (873 aa)
	zwf	Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (490 aa)
	ARD38516.1	Glutathione transferase GstA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily. (201 aa)
	ARD38628.1	Isocitrate dehydrogenase (NADP(+)); Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
	ARD38920.1	Glutathione S-transferase; Catalyzes the formation of 2,4-dinitrophenyl-S-glutathione from 1-chloro-2,4-dinitrobenzene and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
	ARD39017.1	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
	ARD39139.1	Bifunctional glutathionylspermidine amidase/synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa)
	ARD39253.1	Aminopeptidase PepB; Probably plays an important role in intracellular peptide degradation. (433 aa)
	gshA	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (519 aa)
	ARD39448.1	Ornithine decarboxylase SpeF; Derived by automated computational analysis using gene prediction method: Protein Homology. (720 aa)
	pepA	Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (503 aa)
	ARD39722.1	Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
	ARD39796.1	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
	gshB	Glutathione synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family. (316 aa)
	ARD40524.1	Cytosol nonspecific dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
	ARD40823.1	Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa)

Your Current Organism:

Edwardsiella ictaluri

NCBI taxonomy Id: 67780
Other names: ATCC 33202, CCUG 18764, CIP 81.96, DSM 13697, E. ictaluri, JCM 16934, NCTC 12122, SECFDL GA 77-52

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARD38048.1	ARD39017.1	B6E78_00170	B6E78_06090	Derived by automated computational analysis using gene prediction method: Protein Homology.	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.909
ARD38048.1	ARD39253.1	B6E78_00170	B6E78_07540	Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminopeptidase PepB; Probably plays an important role in intracellular peptide degradation.	0.923
ARD38048.1	ARD39796.1	B6E78_00170	B6E78_10775	Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.450
ARD38048.1	ARD40524.1	B6E78_00170	B6E78_15065	Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytosol nonspecific dipeptidase; Catalyzes the hydrolysis of Xaa-His dipeptides; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
ARD38048.1	gshA	B6E78_00170	B6E78_07780	Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.	0.911
ARD38048.1	gshB	B6E78_00170	B6E78_12530	Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.	0.910
ARD38048.1	pepA	B6E78_00170	B6E78_08915	Derived by automated computational analysis using gene prediction method: Protein Homology.	Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.	0.923
ARD38516.1	ARD38920.1	B6E78_03080	B6E78_05520	Glutathione transferase GstA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.	Glutathione S-transferase; Catalyzes the formation of 2,4-dinitrophenyl-S-glutathione from 1-chloro-2,4-dinitrobenzene and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
ARD38516.1	ARD39017.1	B6E78_03080	B6E78_06090	Glutathione transferase GstA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.904
ARD38516.1	ARD39139.1	B6E78_03080	B6E78_06870	Glutathione transferase GstA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.	Bifunctional glutathionylspermidine amidase/synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
ARD38516.1	ARD39722.1	B6E78_03080	B6E78_10305	Glutathione transferase GstA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.	Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
ARD38516.1	ARD39796.1	B6E78_03080	B6E78_10775	Glutathione transferase GstA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
ARD38516.1	gshB	B6E78_03080	B6E78_12530	Glutathione transferase GstA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.	Glutathione synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.	0.922
ARD38920.1	ARD38516.1	B6E78_05520	B6E78_03080	Glutathione S-transferase; Catalyzes the formation of 2,4-dinitrophenyl-S-glutathione from 1-chloro-2,4-dinitrobenzene and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione transferase GstA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.	0.915
ARD38920.1	ARD39017.1	B6E78_05520	B6E78_06090	Glutathione S-transferase; Catalyzes the formation of 2,4-dinitrophenyl-S-glutathione from 1-chloro-2,4-dinitrobenzene and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology.	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.904
ARD38920.1	ARD39139.1	B6E78_05520	B6E78_06870	Glutathione S-transferase; Catalyzes the formation of 2,4-dinitrophenyl-S-glutathione from 1-chloro-2,4-dinitrobenzene and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional glutathionylspermidine amidase/synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
ARD38920.1	ARD39722.1	B6E78_05520	B6E78_10305	Glutathione S-transferase; Catalyzes the formation of 2,4-dinitrophenyl-S-glutathione from 1-chloro-2,4-dinitrobenzene and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
ARD38920.1	ARD39796.1	B6E78_05520	B6E78_10775	Glutathione S-transferase; Catalyzes the formation of 2,4-dinitrophenyl-S-glutathione from 1-chloro-2,4-dinitrobenzene and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
ARD38920.1	gshB	B6E78_05520	B6E78_12530	Glutathione S-transferase; Catalyzes the formation of 2,4-dinitrophenyl-S-glutathione from 1-chloro-2,4-dinitrobenzene and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.	0.904
ARD39017.1	ARD38048.1	B6E78_06090	B6E78_00170	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Derived by automated computational analysis using gene prediction method: Protein Homology.	0.909