STRINGSTRING
CBG68235.1 CBG68235.1 idh idh sacA sacA CBG70083.1 CBG70083.1 CBG70091.1 CBG70091.1 fumB fumB fumC fumC pckG pckG mdh mdh CBG70842.1 CBG70842.1 CBG70843.1 CBG70843.1 bkdH bkdH bkdG bkdG bkdF bkdF bkdC bkdC bkdB bkdB bkdA bkdA CBG72176.1 CBG72176.1 ppc ppc CBG72619.1 CBG72619.1 CBG73234.1 CBG73234.1 fdxA fdxA CBG73320.1 CBG73320.1 CBG73321.1 CBG73321.1 CBG73436.1 CBG73436.1 CBG73702.1 CBG73702.1 CBG73704.1 CBG73704.1 CBG73705.1 CBG73705.1 CBG75142.1 CBG75142.1 pdhA pdhA pdhB pdhB CBG75714.1 CBG75714.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG68235.1Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (895 aa)
idhNADP(+)-dependent isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (739 aa)
sacAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
CBG70083.1Putative 2-oxoglutarate dehydrogenase. (1253 aa)
CBG70091.1Putative malate oxidoreductase; Cluster 0617 with SCAB55931. (413 aa)
fumBFumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (558 aa)
fumCFumarate hydratase C; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
pckGPutative phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (611 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
CBG70842.1Putative oxidoreductase; PMID: 15328113. (645 aa)
CBG70843.1Putative oxidoreductase; PMID: 15328113. (353 aa)
bkdHE2 branched-chain alpha keto acid dehydrogenase system; PMID: 7768860; PMID:15328113. (483 aa)
bkdGE1-beta branched-chain alpha-keto-acid dehydrogenase system; PMID: 7768860; PMID:15328113. (324 aa)
bkdFE1-alpha branched-chain alpha keto acid dehydrogenase system; PMID: 7768860. (451 aa)
bkdCE2 branched-chain alpha keto acid dehydrogenase; PMID: 8002616. (447 aa)
bkdBE1-beta branched-chain alpha keto acid dehydrogenase; PMID: 8002616. (334 aa)
bkdAE1-alpha branched-chain alpha keto acid dehydrogenase; PMID: 8002616. (378 aa)
CBG72176.1Putative citrate synthase; See also SCAB58791 citA; Belongs to the citrate synthase family. (367 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (910 aa)
CBG72619.1Putative malate dehydrogenase; Cluster 0617 with SCAB29861. (470 aa)
CBG73234.1Putative pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (918 aa)
fdxAFerredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (103 aa)
CBG73320.1Putative thiamine-pyrophosphate-binding oxidoreductase subunit. (348 aa)
CBG73321.1Putative thiamine-pyrophosphate-binding oxidoreductase alpha subunit; PMID:15328113. (632 aa)
CBG73436.1Conserved hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa)
CBG73702.1Putative oxoglutarate dehydrogenase (succinyl-transferring); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (900 aa)
CBG73704.1Putative dihydrolipoyllysine-residue succinyltransferase; PMID:8504804; pair of direct repeats and Pro/Ala tract (entirely G/C). (601 aa)
CBG73705.1Putative dihydrolipoamide dehydrogenase; PMID:9858775. (462 aa)
CBG75142.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1126 aa)
pdhAPROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) PDHA (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE). (384 aa)
pdhBPROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (BETA SUBUNIT) PDHB (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE). (339 aa)
CBG75714.1Putative dihydrolipoamide acyltransferase component E2. (546 aa)
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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