STRINGSTRING
CBG69195.1 CBG69195.1 CBG69196.1 CBG69196.1 hemE hemE hemH hemH CBG70944.1 CBG70944.1 CBG70945.1 CBG70945.1 CBG70946.1 CBG70946.1 CBG70947.1 CBG70947.1 CBG70950.1 CBG70950.1 hemL hemL CBG70953.1 CBG70953.1 hemB hemB hemD hemD hemC1 hemC1 hemA hemA rex rex CBG70990.1 CBG70990.1 CBG70991.1 CBG70991.1 CBG70992.1 CBG70992.1 CBG70993.1 CBG70993.1 CBG72371.1 CBG72371.1 CBG72372.1 CBG72372.1 CBG72373.1 CBG72373.1 CBG72614.1 CBG72614.1 CBG72997.1 CBG72997.1 cobS cobS cobT cobT cobU cobU CBG74075.1 CBG74075.1 CBG74076.1 CBG74076.1 cobB cobB cobO cobO CBG74080.1 CBG74080.1 cobQ cobQ cobD cobD CBG74428.1 CBG74428.1 cobT-2 cobT-2 CBG74430.1 CBG74430.1 hemC hemC cbiO cbiO cbiQ cbiQ cbiN cbiN cbiM cbiM CBG76021.1 CBG76021.1 CBG76023.1 CBG76023.1 cobN cobN SCAB_9791 SCAB_9791 cobI cobI SCAB_9811 SCAB_9811 cbiD cbiD cobM cobM cobL cobL
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CBG69195.1Conserved hypothetical protein; PMID:15563836; possibly E.C. 1.13.11: from family similarity to chlorite dismutase 1.13.11.49. (243 aa)
CBG69196.1Putative oxidoreductase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (494 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (359 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (376 aa)
CBG70944.1Putative cytochrome assembly protein. (375 aa)
CBG70945.1Putative cytochrome assembly protein. (585 aa)
CBG70946.1Putative cytochrome related protein. (262 aa)
CBG70947.1Putative secreted redoxin. (188 aa)
CBG70950.1Putative bisphosphoglycerate mutase. (224 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (439 aa)
CBG70953.1Conserved hypothetical protein. (201 aa)
hemBPorphobilinogen synthase; Belongs to the ALAD family. (311 aa)
hemDPutative uroporphyrinogen-III synthase. (583 aa)
hemC1Putative hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (322 aa)
hemAPutative glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (587 aa)
rexRedox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (251 aa)
CBG70990.1Putative redoxin. (95 aa)
CBG70991.1Putative phosphoserine phosphatase; PMID: 10913095. (292 aa)
CBG70992.1AdsA-like sigma factor; PMID:10913094; AdsA is regulated by AdpA in the A factor cascade in S. griseus; Belongs to the sigma-70 factor family. ECF subfamily. (258 aa)
CBG70993.1Putative membrane protein. (414 aa)
CBG72371.1Putative membrane-located cobalamin biosynthesis protein. (357 aa)
CBG72372.1Putative cobalt transporter. (253 aa)
CBG72373.1Putative cobalt ABC transporter system ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (257 aa)
CBG72614.1Putative transcriptional regulator. (384 aa)
CBG72997.1BioY-family membrane protein. (206 aa)
cobSPutative cobalamin-5'-phosphate synthase (EC:2.7.8.26); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (269 aa)
cobTPutativenicotinate-nucleotide-dimethylbenzimida zo lephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (372 aa)
cobUPutative cobalamin biosynthesis protein; Likely adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase activity as in PMID: 7559521. (397 aa)
CBG74075.1Putative cobalamin biosynthesis protein; PMID:14612231; 63.376%aaid to S. seoulensis protein PMID:14612231 involved in superoxide dismutase expression; TTA-Leu codon(s) 27 may indicate regulation by BldA. (313 aa)
CBG74076.1Putative CbiG-like cobalamin biosynthesis protein. (185 aa)
cobBCobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (449 aa)
cobOcob(I)yrinic acid a,c-diamide adenosyltransferase (EC 2.5.1.17). (199 aa)
CBG74080.1Putative chelatase; PMID:2747617. (684 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (508 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (319 aa)
CBG74428.1Putative SAM-dependent methyltransferase. (403 aa)
cobT-2Putative phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (1483 aa)
CBG74430.1Putative uroporphyrin-III methyltransferase. (393 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (296 aa)
cbiOCobalt transport system ATP binding component; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (280 aa)
cbiQCobalt transport system integral membrane component; PMID:7883713. (249 aa)
cbiNPuative cobalt transport protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (144 aa)
cbiMPutative cobalt transport system integral membrane component; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (237 aa)
CBG76021.1Putative precorrin-4 C11-methyltransferase. (172 aa)
CBG76023.1Conserved hypothetical protein. (52 aa)
cobNProbable cobalamin biosynthesis protein cobN. (1209 aa)
SCAB_9791Putative precorrin-8X methylmutase. (234 aa)
cobIPrecorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Probable bifunctional protein, CobI-CobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase. (496 aa)
SCAB_9811Putative precorrin-6X reductase. (247 aa)
cbiDPutative cobalamin biosynthesis-related protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (385 aa)
cobMPrecorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (249 aa)
cobLprecorrin-6Y C5,15-methyltransferase [decarboxylating]. (428 aa)
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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