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deoA deoA hisF hisF cobT-2 cobT-2 apt apt pyrR pyrR hisG hisG kptA kptA nadC nadC CBG71566.1 CBG71566.1 CBG73491.1 CBG73491.1 CBG72673.1 CBG72673.1 CBG72342.1 CBG72342.1 CBG71877.1 CBG71877.1 purF purF upp upp CBG73492.1 CBG73492.1 cobT cobT trpD1 trpD1 CBG73801.1 CBG73801.1 hisH hisH pyrE pyrE hprT hprT CBG68200.1 CBG68200.1 CBG70562.1 CBG70562.1
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query proteins and first shell of interactors
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second shell of interactors
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a 3D structure is known or predicted
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deoAThymidine phosphorylase. (433 aa)
hisFPutative imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (254 aa)
cobT-2Putative phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (1483 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (179 aa)
pyrRPyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (199 aa)
hisGATP phosphoribosyltransferase (EC 2.4.2.17); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (290 aa)
kptAPutative phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (176 aa)
nadCNicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. (327 aa)
CBG71566.1Putative integral membrane protein. (511 aa)
CBG73491.1Putative phage portal protein; PMID:7879712. (447 aa)
CBG72673.1Conserved hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (442 aa)
CBG72342.1Putative methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (304 aa)
CBG71877.1Putative phage protein. (451 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (508 aa)
uppPutative uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)
CBG73492.1Putative phage protein. (232 aa)
cobTPutativenicotinate-nucleotide-dimethylbenzimida zo lephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (372 aa)
trpD1Phosphoribosylanthranilate transferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (351 aa)
CBG73801.1Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (242 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (215 aa)
pyrEPutative orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (184 aa)
hprTPutative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (186 aa)
CBG68200.1Conserved hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (458 aa)
CBG70562.1Putative phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (274 aa)
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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