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deoA | Thymidine phosphorylase. (433 aa) | ||||
hisF | Putative imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (254 aa) | ||||
cobT-2 | Putative phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (1483 aa) | ||||
apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (179 aa) | ||||
pyrR | Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (199 aa) | ||||
hisG | ATP phosphoribosyltransferase (EC 2.4.2.17); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (290 aa) | ||||
kptA | Putative phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (176 aa) | ||||
nadC | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. (327 aa) | ||||
CBG71566.1 | Putative integral membrane protein. (511 aa) | ||||
CBG73491.1 | Putative phage portal protein; PMID:7879712. (447 aa) | ||||
CBG72673.1 | Conserved hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (442 aa) | ||||
CBG72342.1 | Putative methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (304 aa) | ||||
CBG71877.1 | Putative phage protein. (451 aa) | ||||
purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (508 aa) | ||||
upp | Putative uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa) | ||||
CBG73492.1 | Putative phage protein. (232 aa) | ||||
cobT | Putativenicotinate-nucleotide-dimethylbenzimida zo lephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (372 aa) | ||||
trpD1 | Phosphoribosylanthranilate transferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (351 aa) | ||||
CBG73801.1 | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (242 aa) | ||||
hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (215 aa) | ||||
pyrE | Putative orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (184 aa) | ||||
hprT | Putative hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (186 aa) | ||||
CBG68200.1 | Conserved hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (458 aa) | ||||
CBG70562.1 | Putative phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (274 aa) |