STRINGSTRING
sppF sppF CBG75349.1 CBG75349.1 SCAB_8401 SCAB_8401 CBG75352.1 CBG75352.1 CBG75354.1 CBG75354.1 CBG75359.1 CBG75359.1 CBG75492.1 CBG75492.1 CBG75360.1 CBG75360.1 CBG75433.1 CBG75433.1 CBG75445.1 CBG75445.1 SCAB_8521 SCAB_8521 SCAB_8531 SCAB_8531 CBG75821.1 CBG75821.1 CBG75749.1 CBG75749.1 CBG75602.1 CBG75602.1 CBG75566.1 CBG75566.1 CBG68372.1 CBG68372.1 CBG68399.1 CBG68399.1 SCAB_1371 SCAB_1371 CBG68562.1 CBG68562.1 CBG68625.1 CBG68625.1 SCAB_1511 SCAB_1511 CBG68687.1 CBG68687.1 SCAB_1581 SCAB_1581 CBG69089.1 CBG69089.1 SCAB_1971 SCAB_1971 CBG69166.1 CBG69166.1 CBG69167.1 CBG69167.1 CBG69475.1 CBG69475.1 CBG69476.1 CBG69476.1 SCAB_3321 SCAB_3321 SCAB_3341 SCAB_3341 CBG70515.1 CBG70515.1 CBG70934.1 CBG70934.1 CBG70968.1 CBG70968.1 SCAB_4101 SCAB_4101 CBG71232.1 CBG71232.1 CBG71331.1 CBG71331.1 sppB sppB CBG71445.1 CBG71445.1 CBG71600.1 CBG71600.1 CBG71795.1 CBG71795.1 CBG72045.1 CBG72045.1 CBG72177.1 CBG72177.1 CBG72204.1 CBG72204.1 afsR afsR CBG72346.1 CBG72346.1 CBG72877.1 CBG72877.1 CBG73211.1 CBG73211.1 CBG73240.1 CBG73240.1 CBG73433.1 CBG73433.1 CBG74062.1 CBG74062.1 CBG74267.1 CBG74267.1 CBG74563.1 CBG74563.1 CBG74638.1 CBG74638.1 SCAB_7671 SCAB_7671 CBG74723.1 CBG74723.1 CBG75100.1 CBG75100.1 CBG75318.1 CBG75318.1 CBG75339.1 CBG75339.1 CBG75343.1 CBG75343.1 CBG75348.1 CBG75348.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sppFPutative polyketide hydroxylase; PMID:8253693; PMID:8344517; spore pigment. (558 aa)
CBG75349.1Putative NDP-hexose 2,3-dehydratase; PMID:16207901; PMID:12115055; PMID:15271354; PMID:8668120; PMID:11358695. (500 aa)
SCAB_8401Putative para-aminonezoic acid synthase; PMID:8472854; PMID:1178249; PMID:9044253; PMID:14700630; TTA-Leu codon(s) 459 may indicate regulation by BldA. (716 aa)
CBG75352.1Putative carbomoyltransferase. (673 aa)
CBG75354.1Putative dTDP-glucose 4,6-dehydratase; PMID:16207901; PMID:12770825; PMID:16632249; PMID:10770761; polyketide sugar unit biosynthesis?; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (326 aa)
CBG75359.1Putative phosphopantetheinyl transferase; PMID:16207901; PMID:14695521; PMID:21344786; see also SCAB15441, SCAB15451; Belongs to the P-Pant transferase superfamily. (226 aa)
CBG75492.1Putative NRPS/siderophore biosynthesis protein. (6352 aa)
CBG75360.1Putative AfsR-type regulatory protein; PMID:16207901; PMID: 91071605; PMID:12822997; PMID:10517581; TTA-Leu codon(s) 50 may indicate regulation by BldA. (682 aa)
CBG75433.1Putative secreted amidase; PMID:15870355; similar protein queches quorum-sensing homoserine lactone signal. (804 aa)
CBG75445.1Conserved hypothetical protein; Codon 110 TTA-Leu (bldA); homologs in S. coelicolor and S. avermitilis also have TTA; TTA-Leu codon(s) 110 may indicate regulation by BldA. (380 aa)
SCAB_8521Conserved hypothetical protein. (121 aa)
SCAB_8531Conserved hypothetical protein. (410 aa)
CBG75821.1Putative methyltransferase. (567 aa)
CBG75749.1Hypothetical protein. (130 aa)
CBG75602.1Conserved hypothetical protein. (140 aa)
CBG75566.1Putative oxidoreductase; Belongs to the iron/ascorbate-dependent oxidoreductase family. (347 aa)
CBG68372.1Putative isochorismatase; PMID:11591691; PMID:11029592; PMID:8550523; PMID:2521622. (225 aa)
CBG68399.1Putative oxidoreductase; PMID:1650730; PMID:8253693; PMID:10099135. (589 aa)
SCAB_1371Putative AfsR-family regulatory protein; Many more streptomycete homologs. (641 aa)
CBG68562.1Putative oxidoreductase. (596 aa)
CBG68625.1Conserved hypothetical protein. (165 aa)
SCAB_1511Putative carbamoyltransferase. (599 aa)
CBG68687.1Putative phosphopantetheinyl transferase; PMID:16207901; PMID:14695521; PMID:21344786; see also SCAB84091, SCAB84081; Belongs to the P-Pant transferase superfamily. (227 aa)
SCAB_1581Conserved hypothetical protein; Some similar proteins are annotated as phosphopantetheinyl transferases, )BAF92600, EDP57114) but no conserved domain found; may be related to gene cluster SCAB1381-1481. (188 aa)
CBG69089.1Putative NRPS-related protein. (820 aa)
SCAB_1971Putative aminodeoxychorismate synthase; PMID:9044253; PMID:14700630; PMID:14652074; PMID:11782498; PMID:8472954; PMID:15184904; PMID:8704974. (727 aa)
CBG69166.1Putative AfsR-family transcriptional regulator; PMID:14702401; PMID:15113000; PMID:10517581; Possible tandem/partial duplication downstream. (1029 aa)
CBG69167.1Putative AfsR-family transcriptional regulator; Possible tandem/partial duplication from upstream CDS. (677 aa)
CBG69475.1Putative monoxygenase component. (161 aa)
CBG69476.1Putative monooxygenase component; PMID: 15489427. (430 aa)
SCAB_3321Putative non-ribosomal peptide synthetase; PMID:10801488; PMID:9006024; PMID:16647040; PMID:9427658. (5514 aa)
SCAB_3341Putative oxidoreductase; PMID:16208464; PMID:12062399. (333 aa)
CBG70515.1Putative mulitcopper oxidase. (521 aa)
CBG70934.1Putative iron/ascorbate oxidoreductase family protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (333 aa)
CBG70968.1Conserved hypothetical protein. (147 aa)
SCAB_4101Conserved hypothetical protein. (260 aa)
CBG71232.1Conserved hypothetical protein. (130 aa)
CBG71331.1Conserved hypothetical protein. (131 aa)
sppBPutative polyketide beta-ketoacyl synthase 2; PMID: 8344517; PMID: 1644304; PMID: 2077356; PMID:15365693; PMID: 7592377; spore pigment; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (416 aa)
CBG71445.1Conserved hypothetical protein. (131 aa)
CBG71600.1Putative integral membrane protein. (414 aa)
CBG71795.1Putative peptidase family S45 (clan PB(S)); PMID:3680178. (784 aa)
CBG72045.1Conserved hypothetical protein; PMID:10099135. (171 aa)
CBG72177.1Putative iron/ascorbate oxidoreductase family protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (342 aa)
CBG72204.1Putative oxidoreductase. (220 aa)
afsRRegulatory protein; PMID:10517581; PMID:15921897; PMID: 2253887. (994 aa)
CBG72346.1Putative secreted penicillin acylase. (948 aa)
CBG72877.1Putative regulatory protein; PMID:2253887; PMID:16207901; PMID:12822997; PMID:15921897. (1181 aa)
CBG73211.1Putative AfsR-like regulatory protein; PMID:10517581; PMID:15921897; PMID:2253887. (1024 aa)
CBG73240.1Putative secreted protein; TTA-Leu codon(s) 11 may indicate regulation by BldA. (407 aa)
CBG73433.1Putative efflux transporter; Belongs to the major facilitator superfamily. (541 aa)
CBG74062.1Conserved hypothetical protein. (370 aa)
CBG74267.1Putative penicillin acylase. (937 aa)
CBG74563.1Putative integral membrane protein. (238 aa)
CBG74638.1Conserved hypothetical protein. (164 aa)
SCAB_7671Conserved hypothetical protein. (121 aa)
CBG74723.1Conserved hypothetical protein. (142 aa)
CBG75100.1Putative multicopper oxidase. (502 aa)
CBG75318.1Conserved hypothetical protein. (140 aa)
CBG75339.1Putative type I polyketide synthase; PMID:16207901; PMID:16085885; PMID:11094342; PMID:14652074; PMID:10873841; PMID:16806745; TTA-Leu codon(s) 962 may indicate regulation by BldA. (4799 aa)
CBG75343.1Putative type I polyketide synthase; PMID:16207901; PMID:16079135; PMID:11358695. (2049 aa)
CBG75348.1Putative glycosyltransferase; PMID:9561492; PMID:15561847; PMID:12583909. (424 aa)
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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