STRINGSTRING
trpE3 trpE3 CBG74437.1 CBG74437.1 SCAB_8401 SCAB_8401 CBG68373.1 CBG68373.1 SCAB_1381 SCAB_1381 SCAB_1971 SCAB_1971 trpE trpE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
trpE3Putative anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high [...] (492 aa)
CBG74437.1Putative chorismate-binding enzyme. (347 aa)
SCAB_8401Putative para-aminonezoic acid synthase; PMID:8472854; PMID:1178249; PMID:9044253; PMID:14700630; TTA-Leu codon(s) 459 may indicate regulation by BldA. (716 aa)
CBG68373.1Putative chorismate-binding enzyme; PMID:8586283; PMID:9695930; cluster 0359 with SCAB67631 trpE. (732 aa)
SCAB_1381Putative salicylate synthase; TTA-Leu codon(s) 153 may indicate regulation by BldA. (449 aa)
SCAB_1971Putative aminodeoxychorismate synthase; PMID:9044253; PMID:14700630; PMID:14652074; PMID:11782498; PMID:8472954; PMID:15184904; PMID:8704974. (727 aa)
trpEPutative anthranilate synthase; PMID:9695930; PMID:8586283; cluster 0359 with SCAB12051. (620 aa)
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.