STRINGSTRING
CBG68225.1 CBG68225.1 CBG68235.1 CBG68235.1 CBG68239.1 CBG68239.1 CBG68549.1 CBG68549.1 CBG68691.1 CBG68691.1 CBG68949.1 CBG68949.1 CBG68989.1 CBG68989.1 pfkA2 pfkA2 pyk2 pyk2 ppgK ppgK CBG70449.1 CBG70449.1 pckG pckG CBG70538.1 CBG70538.1 CBG70567.1 CBG70567.1 CBG70842.1 CBG70842.1 CBG70843.1 CBG70843.1 CBG71072.1 CBG71072.1 acsA-2 acsA-2 fba fba CBG71289.1 CBG71289.1 bkdH bkdH bkdG bkdG bkdF bkdF bkdC bkdC bkdB bkdB bkdA bkdA gap gap gpmA gpmA CBG72080.1 CBG72080.1 CBG72202.1 CBG72202.1 CBG72206.1 CBG72206.1 CBG72369.1 CBG72369.1 eno eno CBG72904.1 CBG72904.1 CBG72962.1 CBG72962.1 CBG73234.1 CBG73234.1 CBG73313.1 CBG73313.1 CBG73320.1 CBG73320.1 CBG73321.1 CBG73321.1 CBG73393.1 CBG73393.1 CBG73436.1 CBG73436.1 pgm pgm CBG73542.1 CBG73542.1 CBG73561.1 CBG73561.1 CBG73702.1 CBG73702.1 CBG73705.1 CBG73705.1 glkA glkA pfkA1 pfkA1 pyk1 pyk1 gap-2 gap-2 pgk pgk tpiA tpiA pgi2 pgi2 CBG74252.1 CBG74252.1 CBG74253.1 CBG74253.1 CBG74596.1 CBG74596.1 pfkA3 pfkA3 thcA thcA CBG75071.1 CBG75071.1 CBG75227.1 CBG75227.1 agaY agaY CBG75281.1 CBG75281.1 pdhA pdhA pdhB pdhB CBG75714.1 CBG75714.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG68225.1Putative oxidoreductase; Cluster 0095 with SCAB4751, SCAB69701, SCAB83281 gap1/2; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
CBG68235.1Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (895 aa)
CBG68239.1Putative alcohol dehydrogenase. (340 aa)
CBG68549.1Putative oxidoreductase. (379 aa)
CBG68691.1Putative glucosidase. (446 aa)
CBG68949.1Putative sugar kinase. (381 aa)
CBG68989.1Putative acetyl-coenzyme A synthetase. (559 aa)
pfkA26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
pyk2Putative pyruvate kinase; Cluster 0606 with SCAB68861; Belongs to the pyruvate kinase family. (476 aa)
ppgKPolyphosphate glucokinase; PMID:8617763. (248 aa)
CBG70449.1Putative fructose bisphosphatase GlpX. (344 aa)
pckGPutative phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (611 aa)
CBG70538.1Putative dehydrogenase. (347 aa)
CBG70567.1Putative aldehyde dehydrogenase. (478 aa)
CBG70842.1Putative oxidoreductase; PMID: 15328113. (645 aa)
CBG70843.1Putative oxidoreductase; PMID: 15328113. (353 aa)
CBG71072.1Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (486 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
fbaPutative fructose 1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
CBG71289.1Conserved hypothetical protein. (264 aa)
bkdHE2 branched-chain alpha keto acid dehydrogenase system; PMID: 7768860; PMID:15328113. (483 aa)
bkdGE1-beta branched-chain alpha-keto-acid dehydrogenase system; PMID: 7768860; PMID:15328113. (324 aa)
bkdFE1-alpha branched-chain alpha keto acid dehydrogenase system; PMID: 7768860. (451 aa)
bkdCE2 branched-chain alpha keto acid dehydrogenase; PMID: 8002616. (447 aa)
bkdBE1-beta branched-chain alpha keto acid dehydrogenase; PMID: 8002616. (334 aa)
bkdAE1-alpha branched-chain alpha keto acid dehydrogenase; PMID: 8002616. (378 aa)
gapGlyceraldehyde 3-phosphate dehydrogenase; Cluster 0095 with SCAB10521, SCAB69701, SCAB83281; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
CBG72080.1Putative ROK-family regulator. (326 aa)
CBG72202.1Putative alchohol dehydrogenase. (346 aa)
CBG72206.1Conserved hypothetical protein. (750 aa)
CBG72369.1Putative phosphotransferase. (225 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
CBG72904.1Putative alcohol dehydrogenase. (361 aa)
CBG72962.1Putative sugar hydrolase. (421 aa)
CBG73234.1Putative pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (918 aa)
CBG73313.1Putative acyltransferase. (288 aa)
CBG73320.1Putative thiamine-pyrophosphate-binding oxidoreductase subunit. (348 aa)
CBG73321.1Putative thiamine-pyrophosphate-binding oxidoreductase alpha subunit; PMID:15328113. (632 aa)
CBG73393.1Putative aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (347 aa)
CBG73436.1Conserved hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa)
pgmPhosphoglucomutase. (546 aa)
CBG73542.1Putative oxidoreductase; Belongs to the aldehyde dehydrogenase family. (497 aa)
CBG73561.1Putative alcohol dehydrogenase (zinc-binding). (358 aa)
CBG73702.1Putative oxoglutarate dehydrogenase (succinyl-transferring); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (900 aa)
CBG73705.1Putative dihydrolipoamide dehydrogenase; PMID:9858775. (462 aa)
glkAGlucokinase; PMID:15142624; PMID:11386347; PMID:1435260. (317 aa)
pfkA16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
pyk1Putative pyruvate kinase; Cluster 0606 with SCAB28241; Belongs to the pyruvate kinase family. (478 aa)
gap-2Glyceraldehyde-3-phosphate dehydrogenase; Cluster 0095 with SCAB4751, SCAB10521, SCAB83281; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (297 aa)
pgi2Glucose-6-phosphate isomerase; Belongs to the GPI family. (550 aa)
CBG74252.1Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (456 aa)
CBG74253.1Putative zinc-binding alcohol dehydrogenase. (361 aa)
CBG74596.1Putative PTS system sugar phosphotransferase component IIA. (149 aa)
pfkA36-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
thcAAldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
CBG75071.1Putative aldehyde dehydrogenase. (486 aa)
CBG75227.1Putative sugar kinase. (346 aa)
agaYTagatose-bisphosphate aldolase. (293 aa)
CBG75281.1Putative glyceraldehyde-3-phosphate dehydrogenase; Cluster 0095 with SCAB4751, SCAB10521, SCAB69701; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (484 aa)
pdhAPROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) PDHA (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE). (384 aa)
pdhBPROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (BETA SUBUNIT) PDHB (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE). (339 aa)
CBG75714.1Putative dihydrolipoamide acyltransferase component E2. (546 aa)
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.