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CBG68370.1 CBG68370.1 CBG68380.1 CBG68380.1 aroE aroE SCAB_1981 SCAB_1981 aroA2 aroA2 CBG70695.1 CBG70695.1 aspC aspC pat pat CBG71711.1 CBG71711.1 aroQ aroQ trpD1 trpD1 aroH aroH hisC hisC priA priA trpE3 trpE3 trpC1 trpC1 trpB trpB trpA trpA CBG73873.1 CBG73873.1 aroQ-2 aroQ-2 CBG74074.1 CBG74074.1 CBG74185.1 CBG74185.1 CBG74186.1 CBG74186.1 aroE-2 aroE-2 aroC aroC aroK aroK aroB aroB trpF trpF hisC2 hisC2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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CBG68370.1Putative aldolase; PMID: 21475791; PMID:10103039; PMID:12819191; PMID:9426000; cluster 0167 with SCAB67661 and SCAB1981; Belongs to the class-II DAHP synthase family. (412 aa)
CBG68380.1Putative oxidoreductase. (303 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (299 aa)
SCAB_1981Putative aldolase; PMID:8760910; cluster 0167 with SCAB12021 and SCAB67661; Belongs to the class-II DAHP synthase family. (484 aa)
aroA23-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (443 aa)
CBG70695.1Conserved hypothetical protein. (107 aa)
aspCAspartate aminotransferase; PMID: 8675024. (408 aa)
patPutative aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
CBG71711.1Prephenate dehydratase. (311 aa)
aroQPutative chorismate mutase. (218 aa)
trpD1Phosphoribosylanthranilate transferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (351 aa)
aroHPutative 3-deoxy-7-phosphoheptulonate synthase; PMID:8760910; cluster 0167 with SCAB12021 and SCAB1981; Belongs to the class-II DAHP synthase family. (452 aa)
hisCHistidinol-phosphate aminotransferase; PMID:2199329; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)
priAPhosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. (242 aa)
trpE3Putative anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high [...] (492 aa)
trpC1Indoleglycerol phosphate synthase; PMID:10361288; Belongs to the TrpC family. (269 aa)
trpBTryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (427 aa)
trpATryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (272 aa)
CBG73873.1Putative chorismate mutase. (144 aa)
aroQ-2Dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (157 aa)
CBG74074.1Putative cobalamin biosynthesis aminotransferase. (338 aa)
CBG74185.1Putative chorismate mutase. (120 aa)
CBG74186.1Putative secreted prephenate dehydrogenase/chorismate mutase; PMID:12060705; PMID:10770754; PMID:12480894; Cterm duplicated twice downstream: see SCAB71961 and SCAB71971. (361 aa)
aroE-2Quinate/shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. (279 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
trpFPutative N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (221 aa)
hisC2Putative phenylalanine aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (348 aa)
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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