STRINGSTRING
ANP48163.1 ANP48163.1 ANP48228.1 ANP48228.1 ANP48231.1 ANP48231.1 ANP48232.1 ANP48232.1 ANP48233.1 ANP48233.1 ANP48241.1 ANP48241.1 ANP48242.1 ANP48242.1 ANP48243.1 ANP48243.1 ANP56212.1 ANP56212.1 ANP48483.1 ANP48483.1 acsA acsA ANP48597.1 ANP48597.1 ANP48824.1 ANP48824.1 ANP48825.1 ANP48825.1 ANP48976.1 ANP48976.1 sucC sucC sucD sucD folD folD mdh mdh glyA glyA ANP49029.1 ANP49029.1 ANP49030.1 ANP49030.1 ANP49031.1 ANP49031.1 ANP49032.1 ANP49032.1 ANP49040.1 ANP49040.1 ANP49082.1 ANP49082.1 ANP49086.1 ANP49086.1 ANP49109.1 ANP49109.1 ANP49135.1 ANP49135.1 aspA aspA ANP49210.1 ANP49210.1 ANP49213.1 ANP49213.1 ANP49219.1 ANP49219.1 ANP49233.1 ANP49233.1 ANP49234.1 ANP49234.1 ANP49390.1 ANP49390.1 kgd kgd glyA-2 glyA-2 ANP49476.1 ANP49476.1 ANP49489.1 ANP49489.1 ANP49490.1 ANP49490.1 ANP49505.1 ANP49505.1 ANP49511.1 ANP49511.1 ackA ackA ANP49513.1 ANP49513.1 pfkA pfkA ANP49613.1 ANP49613.1 glyA-3 glyA-3 gcvH gcvH gcvT gcvT ANP49662.1 ANP49662.1 ANP49790.1 ANP49790.1 ANP49792.1 ANP49792.1 ANP56406.1 ANP56406.1 ANP49907.1 ANP49907.1 ANP56418.1 ANP56418.1 ANP49960.1 ANP49960.1 ANP50075.1 ANP50075.1 ANP50076.1 ANP50076.1 ANP50077.1 ANP50077.1 ANP50083.1 ANP50083.1 ANP50084.1 ANP50084.1 ANP56445.1 ANP56445.1 ANP50242.1 ANP50242.1 ANP50327.1 ANP50327.1 ANP50331.1 ANP50331.1 ANP50333.1 ANP50333.1 ANP50335.1 ANP50335.1 ANP50391.1 ANP50391.1 ANP50395.1 ANP50395.1 ANP50434.1 ANP50434.1 ANP50449.1 ANP50449.1 ANP56488.1 ANP56488.1 ANP50568.1 ANP50568.1 ANP56491.1 ANP56491.1 ANP50570.1 ANP50570.1 ANP50591.1 ANP50591.1 ANP50617.1 ANP50617.1 ANP50646.1 ANP50646.1 ANP56506.1 ANP56506.1 pgi pgi zwf zwf tal tal ANP56507.1 ANP56507.1 ANP50750.1 ANP50750.1 ANP50751.1 ANP50751.1 ANP50798.1 ANP50798.1 ANP50810.1 ANP50810.1 ANP50811.1 ANP50811.1 ANP50883.1 ANP50883.1 ANP50920.1 ANP50920.1 ANP50973.1 ANP50973.1 sdhA sdhA ANP50975.1 ANP50975.1 ANP56569.1 ANP56569.1 ANP51152.1 ANP51152.1 folD-2 folD-2 AVL59_18225 AVL59_18225 ANP56613.1 ANP56613.1 ANP56615.1 ANP56615.1 ANP51528.1 ANP51528.1 ANP56641.1 ANP56641.1 AVL59_23445 AVL59_23445 ANP52124.1 ANP52124.1 tal-2 tal-2 pgi-2 pgi-2 ANP52127.1 ANP52127.1 pgl pgl zwf-2 zwf-2 ANP56732.1 ANP56732.1 ANP52198.1 ANP52198.1 ANP52257.1 ANP52257.1 ANP52376.1 ANP52376.1 glyA-4 glyA-4 folD-3 folD-3 ANP52492.1 ANP52492.1 ANP52539.1 ANP52539.1 ANP56786.1 ANP56786.1 ANP52646.1 ANP52646.1 ANP52756.1 ANP52756.1 ANP52838.1 ANP52838.1 ANP52869.1 ANP52869.1 ANP52985.1 ANP52985.1 tal-3 tal-3 ANP56851.1 ANP56851.1 ANP53164.1 ANP53164.1 ANP53175.1 ANP53175.1 ANP53200.1 ANP53200.1 ANP53238.1 ANP53238.1 pfkA-2 pfkA-2 gcvP gcvP ANP53875.1 ANP53875.1 ANP54003.1 ANP54003.1 ANP54093.1 ANP54093.1 ANP54099.1 ANP54099.1 ANP54123.1 ANP54123.1 ANP54228.1 ANP54228.1 ANP54352.1 ANP54352.1 tal-4 tal-4 zwf-3 zwf-3 pgl-2 pgl-2 pgi-3 pgi-3 tpiA tpiA pgk pgk ANP54370.1 ANP54370.1 ANP54434.1 ANP54434.1 ANP54450.1 ANP54450.1 ANP54534.1 ANP54534.1 pfp pfp ANP54556.1 ANP54556.1 ANP54605.1 ANP54605.1 ANP54606.1 ANP54606.1 ANP54608.1 ANP54608.1 ANP54711.1 ANP54711.1 ANP54717.1 ANP54717.1 ANP54752.1 ANP54752.1 ANP54791.1 ANP54791.1 ANP54889.1 ANP54889.1 ANP55051.1 ANP55051.1 ANP55070.1 ANP55070.1 ANP55173.1 ANP55173.1 ANP55185.1 ANP55185.1 ANP55223.1 ANP55223.1 ANP55385.1 ANP55385.1 ANP55509.1 ANP55509.1 eno eno prs prs ANP55713.1 ANP55713.1 ANP55738.1 ANP55738.1 ANP55743.1 ANP55743.1 ANP55747.1 ANP55747.1 serC serC ANP55819.1 ANP55819.1 gpmA gpmA ANP56162.1 ANP56162.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANP48163.16-phosphogluconate dehydrogenase (decarboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
ANP48228.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
ANP48231.1Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
ANP48232.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ANP48233.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
ANP48241.1Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
ANP48242.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
ANP48243.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
ANP56212.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
ANP48483.1Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
ANP48597.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (340 aa)
ANP48824.12-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
ANP48825.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
ANP48976.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (481 aa)
ANP49029.1Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (253 aa)
ANP49030.1Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
ANP49031.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
ANP49032.1Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
ANP49040.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (526 aa)
ANP49082.1acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
ANP49086.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
ANP49109.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
ANP49135.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
aspAAspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
ANP49210.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (556 aa)
ANP49213.1Fructose-1,6-bisphosphatase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
ANP49219.1Polyphosphate glucokinase; Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
ANP49233.1Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
ANP49234.1Fumarate reductase/succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
ANP49390.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1268 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
ANP49476.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ANP49489.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
ANP49490.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
ANP49505.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
ANP49511.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (475 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
ANP49513.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (696 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
ANP49613.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (375 aa)
ANP49662.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
ANP49790.1Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (387 aa)
ANP49792.1Formamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
ANP56406.1propionyl-CoA carboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
ANP49907.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
ANP56418.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
ANP49960.1Citrate synthase/methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (387 aa)
ANP50075.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
ANP50076.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (532 aa)
ANP50077.1Isocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
ANP50083.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa)
ANP50084.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)
ANP56445.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
ANP50242.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
ANP50327.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (884 aa)
ANP50331.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
ANP50333.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (342 aa)
ANP50335.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (318 aa)
ANP50391.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
ANP50395.1Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (485 aa)
ANP50434.1Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (541 aa)
ANP50449.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
ANP56488.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (269 aa)
ANP50568.1Protein meaA; Derived by automated computational analysis using gene prediction method: Protein Homology. (675 aa)
ANP56491.1crotonyl-CoA carboxylase/reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
ANP50570.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)
ANP50591.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
ANP50617.1PEP-utilizing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
ANP50646.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (154 aa)
ANP56506.16-phosphogluconate dehydrogenase (decarboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (550 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (530 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (380 aa)
ANP56507.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (691 aa)
ANP50750.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
ANP50751.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (727 aa)
ANP50798.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (392 aa)
ANP50810.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
ANP50811.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
ANP50883.1Isocitrate dehydrogenase, NADP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)
ANP50920.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
ANP50973.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (648 aa)
ANP50975.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
ANP56569.16-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
ANP51152.1Ribose-phosphate pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
folD-2Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa)
AVL59_18225Hypothetical protein; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1124 aa)
ANP56613.1Gluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
ANP56615.1Sugar dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
ANP51528.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
ANP56641.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
AVL59_23445Hydrolytic protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
ANP52124.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (700 aa)
tal-2Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (357 aa)
pgi-2Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (542 aa)
ANP52127.16-phosphogluconate dehydrogenase (decarboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (232 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (469 aa)
ANP56732.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
ANP52198.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (124 aa)
ANP52257.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GcvT family. (340 aa)
ANP52376.1trans-2-enoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TER reductase family. (403 aa)
glyA-4Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
folD-3Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
ANP52492.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
ANP52539.1Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
ANP56786.1acyl-CoA oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
ANP52646.1Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (481 aa)
ANP52756.1Serine/threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
ANP52838.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
ANP52869.1Galactose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
ANP52985.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (233 aa)
tal-3Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (398 aa)
ANP56851.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
ANP53164.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
ANP53175.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
ANP53200.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
ANP53238.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
ANP53875.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
ANP54003.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
ANP54093.1Gluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
ANP54099.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
ANP54123.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
ANP54228.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
ANP54352.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (695 aa)
tal-4Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (372 aa)
zwf-3Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (512 aa)
pgl-26-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (260 aa)
pgi-3Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (550 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (403 aa)
ANP54370.1Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
ANP54434.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (478 aa)
ANP54450.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
ANP54534.1Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (307 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
ANP54556.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
ANP54605.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
ANP54606.12-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
ANP54608.1Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (903 aa)
ANP54711.1Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
ANP54717.1Zn-dependent alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
ANP54752.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
ANP54791.1Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa)
ANP54889.1Pyruvate, phosphate dikinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (906 aa)
ANP55051.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
ANP55070.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (342 aa)
ANP55173.1Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
ANP55185.1Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (429 aa)
ANP55223.1acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
ANP55385.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
ANP55509.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
ANP55713.1Zn-dependent alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
ANP55738.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (366 aa)
ANP55743.1acety-l/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
ANP55747.1Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
ANP55819.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
ANP56162.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
Your Current Organism:
Streptomyces griseochromogenes
NCBI taxonomy Id: 68214
Other names: ATCC 14511, BCRC 11818, CBS 714.72, CCRC 11818, CCRC:11818, DSM 40499, IFO 13413, ISP 5499, JCM 4039, JCM 4764, KCTC 9027, NBRC 13413, NRRL B-12423, NRRL-ISP 5499, S. griseochromogenes, Streptomyces griseichromogenes
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