STRINGSTRING
GCA_000745715_05825 GCA_000745715_05825 GCA_000745715_00013 GCA_000745715_00013 GCA_000745715_00735 GCA_000745715_00735 priA priA ruvB ruvB ruvA ruvA ruvC ruvC GCA_000745715_00972 GCA_000745715_00972 GCA_000745715_01093 GCA_000745715_01093 GCA_000745715_01116 GCA_000745715_01116 GCA_000745715_01117 GCA_000745715_01117 GCA_000745715_01190 GCA_000745715_01190 GCA_000745715_01280 GCA_000745715_01280 GCA_000745715_01298 GCA_000745715_01298 GCA_000745715_01664 GCA_000745715_01664 GCA_000745715_01915 GCA_000745715_01915 GCA_000745715_01934 GCA_000745715_01934 GCA_000745715_02130 GCA_000745715_02130 GCA_000745715_02252 GCA_000745715_02252 GCA_000745715_02299 GCA_000745715_02299 recO recO GCA_000745715_02594 GCA_000745715_02594 GCA_000745715_02621 GCA_000745715_02621 GCA_000745715_02640 GCA_000745715_02640 recR recR GCA_000745715_02809 GCA_000745715_02809 GCA_000745715_02951 GCA_000745715_02951 GCA_000745715_02987 GCA_000745715_02987 recF recF GCA_000745715_03156 GCA_000745715_03156 GCA_000745715_03183 GCA_000745715_03183 GCA_000745715_03460 GCA_000745715_03460 GCA_000745715_03944 GCA_000745715_03944 GCA_000745715_03966 GCA_000745715_03966 polA polA GCA_000745715_04161 GCA_000745715_04161 GCA_000745715_04297 GCA_000745715_04297 GCA_000745715_04398 GCA_000745715_04398 GCA_000745715_04643 GCA_000745715_04643 GCA_000745715_04798 GCA_000745715_04798 GCA_000745715_04894 GCA_000745715_04894 GCA_000745715_04997 GCA_000745715_04997 GCA_000745715_05085 GCA_000745715_05085 GCA_000745715_05086 GCA_000745715_05086 recG recG recA recA GCA_000745715_05360 GCA_000745715_05360 GCA_000745715_05826 GCA_000745715_05826 GCA_000745715_06021 GCA_000745715_06021 GCA_000745715_06137 GCA_000745715_06137 GCA_000745715_06260 GCA_000745715_06260 GCA_000745715_06308 GCA_000745715_06308 GCA_000745715_06574 GCA_000745715_06574 recD2 recD2 GCA_000745715_07181 GCA_000745715_07181 GCA_000745715_07462 GCA_000745715_07462 GCA_000745715_07528 GCA_000745715_07528 GCA_000745715_08057 GCA_000745715_08057 GCA_000745715_08112 GCA_000745715_08112 GCA_000745715_08127 GCA_000745715_08127 GCA_000745715_08139 GCA_000745715_08139 GCA_000745715_08707 GCA_000745715_08707 GCA_000745715_08980 GCA_000745715_08980
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCA_000745715_05825Unannotated protein. (191 aa)
GCA_000745715_00013Unannotated protein. (432 aa)
GCA_000745715_00735Unannotated protein. (345 aa)
priAUnannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (713 aa)
ruvBUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (356 aa)
ruvAUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (201 aa)
ruvCUnannotated protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (183 aa)
GCA_000745715_00972Unannotated protein. (241 aa)
GCA_000745715_01093Unannotated protein. (301 aa)
GCA_000745715_01116Unannotated protein. (354 aa)
GCA_000745715_01117Unannotated protein. (317 aa)
GCA_000745715_01190Unannotated protein. (749 aa)
GCA_000745715_01280Unannotated protein; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (1144 aa)
GCA_000745715_01298Unannotated protein. (350 aa)
GCA_000745715_01664Unannotated protein. (326 aa)
GCA_000745715_01915Unannotated protein. (574 aa)
GCA_000745715_01934Unannotated protein. (542 aa)
GCA_000745715_02130Unannotated protein. (316 aa)
GCA_000745715_02252Unannotated protein. (194 aa)
GCA_000745715_02299Unannotated protein. (372 aa)
recOUnannotated protein; Involved in DNA repair and RecF pathway recombination. (250 aa)
GCA_000745715_02594Unannotated protein. (557 aa)
GCA_000745715_02621Unannotated protein. (401 aa)
GCA_000745715_02640Unannotated protein. (274 aa)
recRUnannotated protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa)
GCA_000745715_02809Unannotated protein. (363 aa)
GCA_000745715_02951Unannotated protein. (681 aa)
GCA_000745715_02987Unannotated protein. (176 aa)
recFUnannotated protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (373 aa)
GCA_000745715_03156Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (376 aa)
GCA_000745715_03183Unannotated protein. (201 aa)
GCA_000745715_03460Unannotated protein. (473 aa)
GCA_000745715_03944Unannotated protein. (667 aa)
GCA_000745715_03966Unannotated protein. (723 aa)
polAUnannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (909 aa)
GCA_000745715_04161Unannotated protein. (1179 aa)
GCA_000745715_04297Unannotated protein. (324 aa)
GCA_000745715_04398Unannotated protein. (531 aa)
GCA_000745715_04643Unannotated protein. (240 aa)
GCA_000745715_04798Unannotated protein. (266 aa)
GCA_000745715_04894Unannotated protein. (327 aa)
GCA_000745715_04997Unannotated protein. (408 aa)
GCA_000745715_05085Unannotated protein. (702 aa)
GCA_000745715_05086Unannotated protein. (192 aa)
recGUnannotated protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (746 aa)
recAUnannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (374 aa)
GCA_000745715_05360Unannotated protein. (273 aa)
GCA_000745715_05826Unannotated protein. (191 aa)
GCA_000745715_06021Unannotated protein. (333 aa)
GCA_000745715_06137Unannotated protein. (215 aa)
GCA_000745715_06260Unannotated protein. (839 aa)
GCA_000745715_06308Unannotated protein. (191 aa)
GCA_000745715_06574Unannotated protein. (153 aa)
recD2Unannotated protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (739 aa)
GCA_000745715_07181Unannotated protein. (644 aa)
GCA_000745715_07462Unannotated protein. (174 aa)
GCA_000745715_07528Unannotated protein. (122 aa)
GCA_000745715_08057Unannotated protein. (836 aa)
GCA_000745715_08112Unannotated protein. (323 aa)
GCA_000745715_08127Unannotated protein. (174 aa)
GCA_000745715_08139Unannotated protein. (334 aa)
GCA_000745715_08707Unannotated protein. (495 aa)
GCA_000745715_08980Unannotated protein. (684 aa)
Your Current Organism:
Streptomyces mirabilis
NCBI taxonomy Id: 68239
Other names: ATCC 27447, Actinomyces mirabilis, CBS 751.72, DSM 40553, IFO 13450, ISP 5553, JCM 4551, JCM 4791, NBRC 13450, NRRL B-2400, NRRL-ISP 5553, S. mirabilis
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