node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AOW85930.1 | AOW91026.1 | BC342_04660 | BC342_06640 | DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.577 |
AOW85930.1 | lexA | BC342_04660 | BC342_26245 | DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.931 |
AOW85930.1 | recA | BC342_04660 | BC342_26085 | DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.920 |
AOW85930.1 | uvrB | BC342_04660 | BC342_07500 | DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.624 |
AOW85930.1 | uvrC | BC342_04660 | BC342_07435 | DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.440 |
AOW88707.1 | AOW90334.1 | BC342_21725 | BC342_31740 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.734 |
AOW88707.1 | AOW91026.1 | BC342_21725 | BC342_06640 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.462 |
AOW88707.1 | lexA | BC342_21725 | BC342_26245 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.731 |
AOW88707.1 | mfd | BC342_21725 | BC342_13485 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.444 |
AOW88707.1 | radA | BC342_21725 | BC342_19615 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.514 |
AOW88707.1 | recA | BC342_21725 | BC342_26085 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.926 |
AOW88707.1 | recR | BC342_21725 | BC342_18130 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.697 |
AOW88707.1 | uvrA | BC342_21725 | BC342_07460 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.787 |
AOW88707.1 | uvrB | BC342_21725 | BC342_07500 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.936 |
AOW88707.1 | uvrC | BC342_21725 | BC342_07435 | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.826 |
AOW90334.1 | AOW88707.1 | BC342_31740 | BC342_21725 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.734 |
AOW90334.1 | AOW91026.1 | BC342_31740 | BC342_06640 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.564 |
AOW90334.1 | lexA | BC342_31740 | BC342_26245 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.428 |
AOW90334.1 | mfd | BC342_31740 | BC342_13485 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.958 |
AOW90334.1 | recA | BC342_31740 | BC342_26085 | ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.667 |