(9 nodes) Non-homologous end-joining network (Streptomyces pactum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOW90605.1	Ku protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
	AOW85499.1	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
	AOW85494.1	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
	AOW88452.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
	AOW89074.1	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
	ku	Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (378 aa)
	nusA	Transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. (344 aa)
	AOW90084.1	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
	AOW90829.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (695 aa)

Your Current Organism:

Streptomyces pactum

NCBI taxonomy Id: 68249
Other names: ATCC 27456, BCRC 12076, CBS 461.69, CBS 734.72, CCRC 12076, CCRC:12076, DSM 40530, IFO 13433, IMET 43357, ISP 5530, JCM 4288, JCM 4809, KCTC 9165, LMG 19357, LMG:19357, NBRC 13433, NCIMB 9445, NRRL 2939, NRRL ISP-5530, NRRL-ISP 5530, S. pactum, Streptomyces pactum var. pactum, Streptomyces pactus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOW85494.1	AOW85499.1	BC342_02005	BC342_02050	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AOW85494.1	AOW89074.1	BC342_02005	BC342_23980	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AOW85494.1	AOW90084.1	BC342_02005	BC342_30240	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AOW85494.1	AOW90605.1	BC342_02005	BC342_33360	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ku protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.870
AOW85494.1	AOW90829.1	BC342_02005	BC342_34730	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.687
AOW85494.1	ku	BC342_02005	BC342_23985	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.868
AOW85499.1	AOW85494.1	BC342_02050	BC342_02005	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AOW85499.1	AOW89074.1	BC342_02050	BC342_23980	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AOW85499.1	AOW90084.1	BC342_02050	BC342_30240	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
AOW85499.1	AOW90605.1	BC342_02050	BC342_33360	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ku protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.941
AOW85499.1	AOW90829.1	BC342_02050	BC342_34730	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.719
AOW85499.1	ku	BC342_02050	BC342_23985	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.941
AOW89074.1	AOW85494.1	BC342_23980	BC342_02005	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AOW89074.1	AOW85499.1	BC342_23980	BC342_02050	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AOW89074.1	AOW90084.1	BC342_23980	BC342_30240	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.892
AOW89074.1	AOW90605.1	BC342_23980	BC342_33360	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ku protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AOW89074.1	ku	BC342_23980	BC342_23985	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.960
AOW90084.1	AOW85494.1	BC342_30240	BC342_02005	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AOW90084.1	AOW85499.1	BC342_30240	BC342_02050	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
AOW90084.1	AOW89074.1	BC342_30240	BC342_23980	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.892

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