(95 nodes) Protein folding, and Protein processing in endoplasmic reticulum network (Tigriopus californicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TCAL_07875	Uncharacterized protein. (527 aa)
	TCAL_01484	Uncharacterized protein. (624 aa)
	TCAL_12247	TPR_REGION domain-containing protein. (506 aa)
	TCAL_01757	Uncharacterized protein. (658 aa)
	TCAL_04182	Aha1_N domain-containing protein. (364 aa)
	TCAL_12267	Uncharacterized protein; Belongs to the heat shock protein 70 family. (510 aa)
	TCAL_01486	J domain-containing protein. (350 aa)
	TCAL_06678	Uncharacterized protein. (159 aa)
	TCAL_02170	J domain-containing protein. (363 aa)
	TCAL_02118	Uncharacterized protein. (533 aa)
	TCAL_03607	Uncharacterized protein. (804 aa)
	TCAL_03631	Uncharacterized protein. (480 aa)
	TCAL_11411	Uncharacterized protein. (225 aa)
	TCAL_12579	Uncharacterized protein; Belongs to the heat shock protein 70 family. (673 aa)
	TCAL_11026	Uncharacterized protein. (261 aa)
	TCAL_03623	DUF775 domain-containing protein. (202 aa)
	TCAL_12594	HpcH_HpaI domain-containing protein. (328 aa)
	TCAL_07161	Uncharacterized protein. (783 aa)
	TCAL_00847	Peptidylprolyl isomerase. (461 aa)
	TCAL_02633	Uncharacterized protein. (412 aa)
	TCAL_02918	Protein disulfide-isomerase. (504 aa)
	TCAL_11129	Uncharacterized protein; Belongs to the protein disulfide isomerase family. (650 aa)
	TCAL_02292	Uncharacterized protein. (515 aa)
	TCAL_06941	J domain-containing protein. (388 aa)
	TCAL_09395	BAG domain-containing protein. (636 aa)
	TCAL_04424	Uncharacterized protein. (339 aa)
	TCAL_04139	Fe2OG dioxygenase domain-containing protein. (338 aa)
	TCAL_04112	Uncharacterized protein. (274 aa)
	TCAL_05614	J domain-containing protein. (367 aa)
	TCAL_05618	Uncharacterized protein. (343 aa)
	TCAL_04102	HATPase_c domain-containing protein. (1022 aa)
	TCAL_02460	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (260 aa)
	TCAL_09618	Ribosomal_L7Ae domain-containing protein. (638 aa)
	TCAL_01247	TPR_REGION domain-containing protein. (2534 aa)
	TCAL_08724	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (950 aa)
	TCAL_01166	ANK_REP_REGION domain-containing protein. (567 aa)
	TCAL_04835	J domain-containing protein. (133 aa)
	TCAL_06128	Uncharacterized protein. (370 aa)
	TCAL_11543	PPIase cyclophilin-type domain-containing protein. (574 aa)
	TCAL_10026	Uncharacterized protein. (258 aa)
	TCAL_08246	J domain-containing protein. (385 aa)
	TCAL_01213	Peptidylprolyl isomerase. (318 aa)
	TCAL_08913	Uncharacterized protein. (391 aa)
	TCAL_10670	Uncharacterized protein. (932 aa)
	TCAL_09987	J domain-containing protein. (487 aa)
	TCAL_09550	Protein disulfide-isomerase. (1024 aa)
	TCAL_05412	Uncharacterized protein; Belongs to the protein disulfide isomerase family. (395 aa)
	TCAL_06728	Uncharacterized protein; Belongs to the heat shock protein 70 family. (578 aa)
	TCAL_17397	Uncharacterized protein; Belongs to the heat shock protein 70 family. (517 aa)
	TCAL_01087	Protein disulfide-isomerase. (545 aa)
	TCAL_12730	Uncharacterized protein. (894 aa)
	TCAL_03946	Uncharacterized protein; Belongs to the heat shock protein 70 family. (568 aa)
	TCAL_06703	P4Hc domain-containing protein. (556 aa)
	TCAL_00905	Protein disulfide-isomerase. (678 aa)
	TCAL_02245	Thioredoxin domain-containing protein. (793 aa)
	TCAL_01534	HATPase_c domain-containing protein. (402 aa)
	TCAL_01546	Uncharacterized protein. (392 aa)
	TCAL_00753	Uncharacterized protein; Belongs to the heat shock protein 70 family. (563 aa)
	TCAL_13523	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (251 aa)
	TCAL_09182	Uncharacterized protein. (502 aa)
	TCAL_04517	Uncharacterized protein; Belongs to the heat shock protein 70 family. (556 aa)
	TCAL_00519	J domain-containing protein. (368 aa)
	TCAL_01287	Protein disulfide-isomerase. (482 aa)
	TCAL_01598	J domain-containing protein. (211 aa)
	TCAL_09500	Calreticulin. (399 aa)
	TCAL_07103	CRIB domain-containing protein. (112 aa)
	TCAL_10497	Serine/threonine-protein phosphatase. (373 aa)
	TCAL_12144	Uncharacterized protein. (186 aa)
	TCAL_09851	Uncharacterized protein. (241 aa)
	TCAL_09850	Uncharacterized protein. (79 aa)
	TCAL_12696	DUF1943 domain-containing protein. (921 aa)
	TCAL_12697	Vitellogenin domain-containing protein. (426 aa)
	TCAL_02698	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (276 aa)
	TCAL_03494	Thioredoxin domain-containing protein. (1634 aa)
	TCAL_12998	Uncharacterized protein. (617 aa)
	TCAL_09580	UBIQUITIN_CONJUGAT_2 domain-containing protein. (603 aa)
	TCAL_15915	Uncharacterized protein. (160 aa)
	TCAL_02721	Uncharacterized protein; Belongs to the heat shock protein 70 family. (703 aa)
	TCAL_03854	Uncharacterized protein. (379 aa)
	TCAL_08136	TPR_REGION domain-containing protein. (337 aa)
	TCAL_14407	J domain-containing protein. (264 aa)
	TCAL_08763	Uncharacterized protein. (613 aa)
	TCAL_09482	Uncharacterized protein; Belongs to the heat shock protein 70 family. (522 aa)
	TCAL_06614	J domain-containing protein. (257 aa)
	TCAL_08958	Uncharacterized protein. (728 aa)
	TCAL_02261	Uncharacterized protein; Belongs to the GroES chaperonin family. (103 aa)
	TCAL_02260	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (645 aa)
	TCAL_06783	Ig-like domain-containing protein. (215 aa)
	TCAL_16023	J domain-containing protein. (89 aa)
	TCAL_08327	J domain-containing protein. (362 aa)
	TCAL_10046	CS domain-containing protein. (192 aa)
	TCAL_12945	Vitellogenin domain-containing protein. (893 aa)
	TCAL_09010	Uncharacterized protein. (151 aa)
	TCAL_09273	J domain-containing protein. (382 aa)
	TCAL_02985	Peptidylprolyl isomerase. (385 aa)

Your Current Organism:

Tigriopus californicus

NCBI taxonomy Id: 6832
Other names: T. californicus, tidepool copepod

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TCAL_00519	TCAL_00753	A0A553PB53	A0A553PA15	J domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.806
TCAL_00519	TCAL_01166	A0A553PB53	A0A553NY57	J domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.680
TCAL_00519	TCAL_01247	A0A553PB53	A0A553NWY1	J domain-containing protein.	TPR_REGION domain-containing protein.	0.591
TCAL_00519	TCAL_01534	A0A553PB53	A0A553P6R0	J domain-containing protein.	HATPase_c domain-containing protein.	0.789
TCAL_00519	TCAL_01757	A0A553PB53	A0A553N7J2	J domain-containing protein.	Uncharacterized protein.	0.750
TCAL_00519	TCAL_02260	A0A553PB53	A0A553PP16	J domain-containing protein.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.403
TCAL_00519	TCAL_02261	A0A553PB53	A0A553PP05	J domain-containing protein.	Uncharacterized protein; Belongs to the GroES chaperonin family.	0.514
TCAL_00519	TCAL_02292	A0A553PB53	A0A553NQK4	J domain-containing protein.	Uncharacterized protein.	0.690
TCAL_00519	TCAL_02460	A0A553PB53	A0A553NVB2	J domain-containing protein.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.649
TCAL_00519	TCAL_02633	A0A553PB53	A0A553NG23	J domain-containing protein.	Uncharacterized protein.	0.821
TCAL_00519	TCAL_02721	A0A553PB53	A0A553PH86	J domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.804
TCAL_00519	TCAL_03623	A0A553PB53	A0A553NF54	J domain-containing protein.	DUF775 domain-containing protein.	0.626
TCAL_00519	TCAL_03631	A0A553PB53	A0A553NCE0	J domain-containing protein.	Uncharacterized protein.	0.474
TCAL_00519	TCAL_03946	A0A553PB53	A0A553P4M2	J domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.822
TCAL_00519	TCAL_04102	A0A553PB53	A0A553NV84	J domain-containing protein.	HATPase_c domain-containing protein.	0.728
TCAL_00519	TCAL_04182	A0A553PB53	A0A553N8E3	J domain-containing protein.	Aha1_N domain-containing protein.	0.601
TCAL_00519	TCAL_04424	A0A553PB53	A0A553NUE9	J domain-containing protein.	Uncharacterized protein.	0.823
TCAL_00519	TCAL_04517	A0A553PB53	A0A553PB35	J domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.822
TCAL_00519	TCAL_05618	A0A553PB53	A0A553NUT4	J domain-containing protein.	Uncharacterized protein.	0.484
TCAL_00519	TCAL_06728	A0A553PB53	A0A553P3A6	J domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.823