(45 nodes) Cellular response to topologically incorrect protein network (Tigriopus californicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TCAL_01757	Uncharacterized protein. (658 aa)
	TCAL_08281	BTB domain-containing protein. (410 aa)
	TCAL_12255	Uncharacterized protein; Belongs to the BI1 family. (236 aa)
	TCAL_02113	Ubiquitin-like domain-containing protein. (427 aa)
	TCAL_11709	DUF4203 domain-containing protein. (640 aa)
	TCAL_03607	Uncharacterized protein. (804 aa)
	TCAL_05583	Uncharacterized protein. (249 aa)
	TCAL_12579	Uncharacterized protein; Belongs to the heat shock protein 70 family. (673 aa)
	TCAL_00856	WD_REPEATS_REGION domain-containing protein. (455 aa)
	TCAL_02594	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (985 aa)
	TCAL_06293	Uncharacterized protein. (512 aa)
	TCAL_00352	BZIP domain-containing protein. (762 aa)
	TCAL_09236	Poly [ADP-ribose] polymerase. (331 aa)
	TCAL_02919	Uncharacterized protein. (381 aa)
	TCAL_03469	BZIP domain-containing protein. (596 aa)
	TCAL_15875	Uncharacterized protein. (66 aa)
	TCAL_04145	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (259 aa)
	TCAL_01386	Uncharacterized protein. (567 aa)
	TCAL_04132	PRKCSH domain-containing protein. (797 aa)
	TCAL_02515	Uncharacterized protein. (1298 aa)
	TCAL_10293	BTB domain-containing protein. (405 aa)
	TCAL_01187	Uncharacterized protein. (370 aa)
	TCAL_01054	Uncharacterized protein. (379 aa)
	TCAL_09055	RING-type domain-containing protein. (711 aa)
	TCAL_17151	Uncharacterized protein. (647 aa)
	TCAL_09115	BZIP domain-containing protein. (406 aa)
	TCAL_11090	Uncharacterized protein. (348 aa)
	TCAL_01513	RING-type domain-containing protein. (361 aa)
	TCAL_01574	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (767 aa)
	TCAL_06696	CULLIN_2 domain-containing protein; Belongs to the cullin family. (770 aa)
	TCAL_00753	Uncharacterized protein; Belongs to the heat shock protein 70 family. (563 aa)
	TCAL_00559	Uncharacterized protein. (371 aa)
	TCAL_09851	Uncharacterized protein. (241 aa)
	TCAL_09852	BTB domain-containing protein. (144 aa)
	TCAL_09850	Uncharacterized protein. (79 aa)
	TCAL_00135	Uncharacterized protein. (1550 aa)
	TCAL_09223	Uncharacterized protein. (230 aa)
	TCAL_03837	Protein kinase domain-containing protein. (994 aa)
	TCAL_02721	Uncharacterized protein; Belongs to the heat shock protein 70 family. (703 aa)
	TCAL_00109	Uncharacterized protein. (65 aa)
	TCAL_11600	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (275 aa)
	TCAL_02260	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (645 aa)
	TCAL_11365	RING-type domain-containing protein. (520 aa)
	TCAL_08098	Glucosylceramidase. (1042 aa)
	TCAL_09273	J domain-containing protein. (382 aa)

Your Current Organism:

Tigriopus californicus

NCBI taxonomy Id: 6832
Other names: T. californicus, tidepool copepod

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TCAL_00135	TCAL_01386	A0A553PFX1	A0A553NSS2	Uncharacterized protein.	Uncharacterized protein.	0.530
TCAL_00135	TCAL_01574	A0A553PFX1	A0A553P709	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.625
TCAL_00135	TCAL_03607	A0A553PFX1	A0A553NBA4	Uncharacterized protein.	Uncharacterized protein.	0.707
TCAL_00135	TCAL_04132	A0A553PFX1	A0A553NTV2	Uncharacterized protein.	PRKCSH domain-containing protein.	0.530
TCAL_00135	TCAL_12255	A0A553PFX1	A0A553N9H2	Uncharacterized protein.	Uncharacterized protein; Belongs to the BI1 family.	0.596
TCAL_00352	TCAL_00753	A0A553NFF7	A0A553PA15	BZIP domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.714
TCAL_00352	TCAL_02515	A0A553NFF7	A0A553NUN3	BZIP domain-containing protein.	Uncharacterized protein.	0.655
TCAL_00352	TCAL_02721	A0A553NFF7	A0A553PH86	BZIP domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.404
TCAL_00352	TCAL_03469	A0A553NFF7	A0A553NQ90	BZIP domain-containing protein.	BZIP domain-containing protein.	0.841
TCAL_00352	TCAL_03837	A0A553NFF7	A0A553PGQ4	BZIP domain-containing protein.	Protein kinase domain-containing protein.	0.668
TCAL_00352	TCAL_09115	A0A553NFF7	A0A553P5P1	BZIP domain-containing protein.	BZIP domain-containing protein.	0.860
TCAL_00352	TCAL_09850	A0A553NFF7	A0A553PDH4	BZIP domain-containing protein.	Uncharacterized protein.	0.714
TCAL_00352	TCAL_09851	A0A553NFF7	A0A553PDH0	BZIP domain-containing protein.	Uncharacterized protein.	0.714
TCAL_00352	TCAL_12579	A0A553NFF7	A0A553NEI4	BZIP domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.714
TCAL_00559	TCAL_04145	A0A553PAN7	A0A553NS81	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.746
TCAL_00559	TCAL_11600	A0A553PAN7	A0A553PLT2	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.480
TCAL_00753	TCAL_00352	A0A553PA15	A0A553NFF7	Uncharacterized protein; Belongs to the heat shock protein 70 family.	BZIP domain-containing protein.	0.714
TCAL_00753	TCAL_01386	A0A553PA15	A0A553NSS2	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.497
TCAL_00753	TCAL_01757	A0A553PA15	A0A553N7J2	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.789
TCAL_00753	TCAL_02260	A0A553PA15	A0A553PP16	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.693