STRINGSTRING
SCL51699.1 SCL51699.1 SCL46770.1 SCL46770.1 SCL47481.1 SCL47481.1 SCL47552.1 SCL47552.1 SCL48179.1 SCL48179.1 SCL48539.1 SCL48539.1 metG metG SCL49279.1 SCL49279.1 trpS trpS SCL49799.1 SCL49799.1 SCL50841.1 SCL50841.1 SCL50989.1 SCL50989.1 SCL50991.1 SCL50991.1 mnmA mnmA coaD coaD SCL52362.1 SCL52362.1 SCL52397.1 SCL52397.1 SCL52403.1 SCL52403.1 SCL53122.1 SCL53122.1 SCL53447.1 SCL53447.1 SCL54066.1 SCL54066.1 tyrS tyrS SCL54722.1 SCL54722.1 SCL55396.1 SCL55396.1 SCL56029.1 SCL56029.1 SCL56327.1 SCL56327.1 mshC mshC SCL57267.1 SCL57267.1 SCL58393.1 SCL58393.1 SCL58929.1 SCL58929.1 SCL59223.1 SCL59223.1 leuS leuS nadE nadE argG argG gltX gltX nadD nadD SCL61412.1 SCL61412.1 valS valS argS argS cysH cysH valS-2 valS-2 SCL62916.1 SCL62916.1 guaA guaA cysS cysS panC panC tilS tilS ileS ileS SCL65772.1 SCL65772.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCL51699.1Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (320 aa)
SCL46770.1Deoxyribodipyrimidine photo-lyase; Belongs to the DNA photolyase family. (438 aa)
SCL47481.1rfaE bifunctional protein, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (662 aa)
SCL47552.1rfaE bifunctional protein, domain II. (160 aa)
SCL48179.1DUF218 domain-containing protein. (220 aa)
SCL48539.1DNA sulfur modification protein DndC. (514 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (600 aa)
SCL49279.1Sulfate adenylyltransferase subunit 2. (303 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (341 aa)
SCL49799.1Asparagine synthase (glutamine-hydrolysing). (594 aa)
SCL50841.1Asparagine synthase (glutamine-hydrolysing). (611 aa)
SCL50989.1Electron transfer flavoprotein beta subunit. (259 aa)
SCL50991.1Electron transfer flavoprotein alpha subunit apoprotein. (319 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (357 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
SCL52362.1Asparagine synthase (glutamine-hydrolysing). (398 aa)
SCL52397.1Nucleotide-binding universal stress protein, UspA family. (299 aa)
SCL52403.1Nucleotide-binding universal stress protein, UspA family. (275 aa)
SCL53122.1Asparagine synthase (glutamine-hydrolysing). (608 aa)
SCL53447.1rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (537 aa)
SCL54066.1Nucleotide-binding universal stress protein, UspA family. (292 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (429 aa)
SCL54722.1Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (146 aa)
SCL55396.1Sulfate adenylyltransferase subunit 2. (304 aa)
SCL56029.1Asparagine synthase (glutamine-hydrolysing). (591 aa)
SCL56327.1Nucleotide-binding universal stress protein, UspA family. (289 aa)
mshCL-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (412 aa)
SCL57267.1Deoxyribodipyrimidine photolyase-related protein. (482 aa)
SCL58393.1Osmosensitive K+ channel signal transduction histidine kinase. (850 aa)
SCL58929.1Asparagine synthase (glutamine-hydrolysing). (667 aa)
SCL59223.1Nicotinamide-nucleotide adenylyltransferase, NadR type. (388 aa)
leuSleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (946 aa)
nadENAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (590 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (482 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (469 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (189 aa)
SCL61412.1Deoxyribodipyrimidine photolyase-related protein. (490 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (872 aa)
argSarginyl-tRNA synthetase. (554 aa)
cysHPhosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (248 aa)
valS-2valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (936 aa)
SCL62916.1Sulfate adenylyltransferase. (509 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (518 aa)
cysScysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (471 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (328 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1040 aa)
SCL65772.1Asparagine synthase (glutamine-hydrolysing). (611 aa)
Your Current Organism:
Micromonospora yangpuensis
NCBI taxonomy Id: 683228
Other names: CGMCC 4.5736, DSM 45577, M. yangpuensis, Micromonospora sp. FXJ6.011, Micromonospora yangpuensis Zhang et al. 2012, NBRC 107727, strain FXJ6.011
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