STRINGSTRING
SCL65040.1 SCL65040.1 SCL46262.1 SCL46262.1 SCL46617.1 SCL46617.1 SCL46711.1 SCL46711.1 SCL46782.1 SCL46782.1 SCL47042.1 SCL47042.1 acsA acsA SCL47569.1 SCL47569.1 SCL47805.1 SCL47805.1 SCL47905.1 SCL47905.1 SCL49444.1 SCL49444.1 SCL49509.1 SCL49509.1 SCL49553.1 SCL49553.1 SCL49766.1 SCL49766.1 SCL50851.1 SCL50851.1 SCL50958.1 SCL50958.1 SCL51599.1 SCL51599.1 SCL51987.1 SCL51987.1 SCL52125.1 SCL52125.1 SCL52809.1 SCL52809.1 SCL52843.1 SCL52843.1 SCL53234.1 SCL53234.1 SCL54481.1 SCL54481.1 SCL54950.1 SCL54950.1 SCL55055.1 SCL55055.1 SCL55272.1 SCL55272.1 SCL55318.1 SCL55318.1 SCL55827.1 SCL55827.1 SCL55908.1 SCL55908.1 SCL55914.1 SCL55914.1 SCL56598.1 SCL56598.1 SCL56602.1 SCL56602.1 accA accA SCL57378.1 SCL57378.1 SCL58160.1 SCL58160.1 SCL58488.1 SCL58488.1 SCL58535.1 SCL58535.1 SCL58550.1 SCL58550.1 SCL58553.1 SCL58553.1 SCL59000.1 SCL59000.1 SCL59963.1 SCL59963.1 SCL60078.1 SCL60078.1 SCL60327.1 SCL60327.1 SCL60405.1 SCL60405.1 SCL60495.1 SCL60495.1 SCL60808.1 SCL60808.1 SCL60906.1 SCL60906.1 SCL61962.1 SCL61962.1 SCL61979.1 SCL61979.1 SCL61987.1 SCL61987.1 SCL62430.1 SCL62430.1 ackA ackA SCL62510.1 SCL62510.1 sucD sucD sucC sucC SCL62962.1 SCL62962.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCL65040.1propionyl-CoA carboxylase alpha chain. (653 aa)
SCL46262.1acetyl-CoA carboxylase, biotin carboxylase subunit. (445 aa)
SCL46617.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
SCL46711.1DNA binding domain-containing protein, excisionase family. (69 aa)
SCL46782.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. (527 aa)
SCL47042.1DNA binding domain-containing protein, excisionase family. (88 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (663 aa)
SCL47569.1TIGR03089 family protein. (250 aa)
SCL47805.1Argininosuccinate lyase. (429 aa)
SCL47905.1Predicted site-specific integrase-resolvase. (197 aa)
SCL49444.1methylmalonyl-CoA mutase. (527 aa)
SCL49509.1Biotin carboxyl carrier protein /biotin carboxylase. (583 aa)
SCL49553.1propionyl-CoA carboxylase carboxyltransferase subunit. (527 aa)
SCL49766.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
SCL50851.1Biotin carboxylase. (617 aa)
SCL50958.1Enoyl-CoA hydratase/carnithine racemase. (257 aa)
SCL51599.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
SCL51987.1Acyl-CoA synthetase (NDP forming). (853 aa)
SCL52125.13-hydroxyacyl-CoA dehydrogenase. (700 aa)
SCL52809.1acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein. (580 aa)
SCL52843.1acetyl-CoA carboxylase carboxyltransferase subunit beta /acetyl-CoA carboxylase carboxyltransferase subunit alpha. (516 aa)
SCL53234.1Threonine dehydrogenase. (394 aa)
SCL54481.12-methylcitrate dehydratase PrpD. (516 aa)
SCL54950.1Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase. (496 aa)
SCL55055.1Acyl-coenzyme A oxidase. (663 aa)
SCL55272.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
SCL55318.1Enoyl-CoA hydratase/carnithine racemase. (323 aa)
SCL55827.12-methylcitrate dehydratase PrpD. (498 aa)
SCL55908.1Phosphoenolpyruvate mutase. (297 aa)
SCL55914.1Acetoacetate decarboxylase (ADC). (268 aa)
SCL56598.1acetyl-CoA carboxylase, biotin carboxylase subunit. (483 aa)
SCL56602.1acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (575 aa)
SCL57378.1Dye decolorizing peroxidase. (409 aa)
SCL58160.12,3-dimethylmalate lyase. (293 aa)
SCL58488.1Dye decolorizing peroxidase. (426 aa)
SCL58535.1enoyl-CoA hydratase. (348 aa)
SCL58550.1Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (303 aa)
SCL58553.12-methylcitrate dehydratase. (519 aa)
SCL59000.1Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
SCL59963.1Dihydrolipoamide dehydrogenase. (476 aa)
SCL60078.1Muramoyltetrapeptide carboxypeptidase. (322 aa)
SCL60327.12-oxoisovalerate dehydrogenase E1 component. (1104 aa)
SCL60405.1acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit. (473 aa)
SCL60495.1Threonine dehydrogenase. (390 aa)
SCL60808.12-oxoisovalerate dehydrogenase E1 component. (731 aa)
SCL60906.1Biotin carboxylase. (417 aa)
SCL61962.1methylmalonyl-CoA mutase, N-terminal domain. (562 aa)
SCL61979.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
SCL61987.1methylmalonyl-CoA epimerase. (155 aa)
SCL62430.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (689 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (372 aa)
SCL62510.1Biotin-requiring enzyme. (71 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
SCL62962.1isobutyryl-CoA mutase small subunit. (134 aa)
Your Current Organism:
Micromonospora yangpuensis
NCBI taxonomy Id: 683228
Other names: CGMCC 4.5736, DSM 45577, M. yangpuensis, Micromonospora sp. FXJ6.011, Micromonospora yangpuensis Zhang et al. 2012, NBRC 107727, strain FXJ6.011
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