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| purN | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (224 aa) | ||||
| SCL64503.1 | Hypothetical protein. (357 aa) | ||||
| SCL60024.1 | Uncharacterized membrane protein YckC, RDD family. (134 aa) | ||||
| SCL64745.1 | RDD family protein. (385 aa) | ||||
| SCL50756.1 | 5-formyltetrahydrofolate cyclo-ligase. (249 aa) | ||||
| SCL49836.1 | HNH endonuclease. (318 aa) | ||||
| SCL49146.1 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (219 aa) | ||||
| SCL59953.1 | Aminomethyltransferase. (374 aa) | ||||
| SCL59745.1 | 5-formyltetrahydrofolate cyclo-ligase. (239 aa) | ||||
| SCL59678.1 | 5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. (304 aa) | ||||
| SCL58074.1 | Protein of unknown function. (400 aa) | ||||
| SCL56929.1 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1171 aa) | ||||
| glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (479 aa) | ||||
| SCL54757.1 | Dihydrofolate reductase. (197 aa) | ||||
| SCL54168.1 | Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (359 aa) | ||||
| fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (308 aa) | ||||
| thyX | Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (245 aa) | ||||
| SCL48556.1 | HNH endonuclease. (313 aa) | ||||
| SCL47771.1 | Dihydrofolate reductase. (202 aa) | ||||
| SCL46741.1 | Protein of unknown function. (235 aa) | ||||
| SCL46197.1 | RDD family protein. (130 aa) | ||||
| SCL60299.1 | Dihydrofolate reductase. (189 aa) | ||||
| SCL61556.1 | 5-methylcytosine-specific restriction endonuclease McrA. (178 aa) | ||||
| folD | 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) | ||||
| purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. (523 aa) | ||||