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A0A1E3NWW5 A0A1E3NWW5 A0A1E3NTY7 A0A1E3NTY7 A0A1E3NUS0 A0A1E3NUS0 A0A1E3NUZ3 A0A1E3NUZ3 A0A1E3NVE6 A0A1E3NVE6 A0A1E3NWE2 A0A1E3NWE2 A0A1E3NWK2 A0A1E3NWK2 A0A1E3NWQ2 A0A1E3NWQ2 A0A1E3NYG4 A0A1E3NYG4 A0A1E3NYX9 A0A1E3NYX9 A0A1E3NZ11 A0A1E3NZ11 A0A1E3NZK7 A0A1E3NZK7 A0A1E3P0U7 A0A1E3P0U7 A0A1E3P0Z4 A0A1E3P0Z4 A0A1E3P165 A0A1E3P165 A0A1E3P1E0 A0A1E3P1E0 A0A1E3P1P2 A0A1E3P1P2 A0A1E3P1U0 A0A1E3P1U0 A0A1E3P298 A0A1E3P298 A0A1E3P2G6 A0A1E3P2G6 A0A1E3P2N5 A0A1E3P2N5 A0A1E3P2P4 A0A1E3P2P4 A0A1E3P2S9 A0A1E3P2S9 A0A1E3P2V2 A0A1E3P2V2 A0A1E3P389 A0A1E3P389 A0A1E3P3A5 A0A1E3P3A5 A0A1E3P3G1 A0A1E3P3G1 A0A1E3P451 A0A1E3P451 A0A1E3P459 A0A1E3P459 A0A1E3P4A2 A0A1E3P4A2 A0A1E3P4H4 A0A1E3P4H4 A0A1E3P4S3 A0A1E3P4S3 MDM34 MDM34 A0A1E3P5B7 A0A1E3P5B7 A0A1E3P5C6 A0A1E3P5C6 A0A1E3P5V2 A0A1E3P5V2 A0A1E3P7D7 A0A1E3P7D7 A0A1E3P883 A0A1E3P883 A0A1E3P8D4 A0A1E3P8D4 A0A1E3P8D5 A0A1E3P8D5 A0A1E3P8T6 A0A1E3P8T6 A0A1E3P9I5 A0A1E3P9I5 A0A1E3P9R8 A0A1E3P9R8 A0A1E3PAI7 A0A1E3PAI7 A0A1E3PAS7 A0A1E3PAS7 A0A1E3PAU8 A0A1E3PAU8 A0A1E3PAW1 A0A1E3PAW1 A0A1E3PAX6 A0A1E3PAX6 A0A1E3PB38 A0A1E3PB38 A0A1E3PB98 A0A1E3PB98 A0A1E3PB99 A0A1E3PB99 A0A1E3PBL8 A0A1E3PBL8 A0A1E3PBR1 A0A1E3PBR1 A0A1E3PBY9 A0A1E3PBY9 A0A1E3PCA7 A0A1E3PCA7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1E3NWW5Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2706 aa)
A0A1E3NTY7Carbohydrate-binding module family 48 protein. (420 aa)
A0A1E3NUS0Uncharacterized protein. (454 aa)
A0A1E3NUZ3Uncharacterized protein. (178 aa)
A0A1E3NVE6Ubiquitin-like domain-containing protein. (152 aa)
A0A1E3NWE2Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (277 aa)
A0A1E3NWK2Protein kinase domain-containing protein. (712 aa)
A0A1E3NWQ2Uncharacterized protein. (149 aa)
A0A1E3NYG4Uncharacterized protein. (157 aa)
A0A1E3NYX9Autophagy-related protein 3. (315 aa)
A0A1E3NZ11Uncharacterized protein. (386 aa)
A0A1E3NZK7Uncharacterized protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (476 aa)
A0A1E3P0U7Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (263 aa)
A0A1E3P0Z4Uncharacterized protein. (535 aa)
A0A1E3P165Ubiquitin carboxyl-terminal hydrolase. (511 aa)
A0A1E3P1E0Uncharacterized protein. (608 aa)
A0A1E3P1P2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (340 aa)
A0A1E3P1U0Uncharacterized protein. (712 aa)
A0A1E3P298Uncharacterized protein. (379 aa)
A0A1E3P2G6Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (574 aa)
A0A1E3P2N5Uncharacterized protein. (169 aa)
A0A1E3P2P4Uncharacterized protein. (307 aa)
A0A1E3P2S9UBIQUITIN_CONJUGAT_2 domain-containing protein. (138 aa)
A0A1E3P2V2Uncharacterized protein. (294 aa)
A0A1E3P389Uncharacterized protein. (227 aa)
A0A1E3P3A5Uncharacterized protein. (389 aa)
A0A1E3P3G1Uncharacterized protein. (224 aa)
A0A1E3P451Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (251 aa)
A0A1E3P459Uncharacterized protein. (71 aa)
A0A1E3P4A2Uncharacterized protein. (221 aa)
A0A1E3P4H4Carbohydrate-binding module family 48 protein. (380 aa)
A0A1E3P4S3Carbohydrate-binding module family 48 protein. (418 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (463 aa)
A0A1E3P5B7Phosphatidylinositol 3-kinase VPS34. (831 aa)
A0A1E3P5C6Uncharacterized protein. (150 aa)
A0A1E3P5V2UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
A0A1E3P7D7RBR-type E3 ubiquitin transferase. (462 aa)
A0A1E3P883Uncharacterized protein. (1392 aa)
A0A1E3P8D4Non-specific serine/threonine protein kinase. (577 aa)
A0A1E3P8D5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (438 aa)
A0A1E3P8T6Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (845 aa)
A0A1E3P9I5Protein kinase domain-containing protein. (797 aa)
A0A1E3P9R8Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (620 aa)
A0A1E3PAI7Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (540 aa)
A0A1E3PAS7Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (297 aa)
A0A1E3PAU8Uncharacterized protein. (414 aa)
A0A1E3PAW1Autophagy-related protein. (133 aa)
A0A1E3PAX6ATG16 domain-containing protein. (191 aa)
A0A1E3PB38SMP-LTD domain-containing protein. (432 aa)
A0A1E3PB98Myotubularin phosphatase domain-containing protein. (705 aa)
A0A1E3PB99TPR_REGION domain-containing protein. (588 aa)
A0A1E3PBL8Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
A0A1E3PBR1Uncharacterized protein. (56 aa)
A0A1E3PBY9Non-specific serine/threonine protein kinase. (1121 aa)
A0A1E3PCA7Uncharacterized protein. (375 aa)
Your Current Organism:
Wickerhamomyces anomalus
NCBI taxonomy Id: 683960
Other names: Pichia anomala NRRL Y-366-8, W. anomalus NRRL Y-366-8, Wickerhamomyces anomalus NRRL Y-366-8
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