(21 nodes) Lagging Strand Synthesis network (Batrachochytrium dendrobatidis JAM81)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (388 aa)
	F4NUJ4_BATDJ	Uncharacterized protein. (2388 aa)
	F4NUZ3_BATDJ	AAA domain-containing protein. (358 aa)
	F4NWW9_BATDJ	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2300 aa)
	F4NX88_BATDJ	AAA domain-containing protein. (340 aa)
	F4NXH5_BATDJ	DNA ligase. (621 aa)
	F4NY69_BATDJ	AAA domain-containing protein. (353 aa)
	F4NYM8_BATDJ	Uncharacterized protein. (414 aa)
	F4NZN4_BATDJ	Uncharacterized protein. (197 aa)
	BATDEDRAFT_653	BRCT domain-containing protein. (696 aa)
	F4P3N4_BATDJ	DNA polymerase. (1125 aa)
	F4P3X9_BATDJ	ATPase_AAA_core domain-containing protein. (1234 aa)
	F4P4N8_BATDJ	DNA_pol_E_B domain-containing protein. (648 aa)
	F4P5H8_BATDJ	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (405 aa)
	F4P658_BATDJ	Expressed protein. (467 aa)
	F4P6Q4_BATDJ	Uncharacterized protein. (501 aa)
	F4P7V0_BATDJ	CBFD_NFYB_HMF domain-containing protein. (258 aa)
	F4P9K5_BATDJ	Uncharacterized protein. (434 aa)
	F4PA52_BATDJ	Uncharacterized protein. (1014 aa)
	F4PBD2_BATDJ	AAA domain-containing protein. (326 aa)
	F4PDT6_BATDJ	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)

Your Current Organism:

Batrachochytrium dendrobatidis JAM81

NCBI taxonomy Id: 684364
Other names: B. dendrobatidis JAM81

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BATDEDRAFT_653	F4NUJ4_BATDJ	F4P1Z1	F4NUJ4	BRCT domain-containing protein.	Uncharacterized protein.	0.787
BATDEDRAFT_653	F4NUZ3_BATDJ	F4P1Z1	F4NUZ3	BRCT domain-containing protein.	AAA domain-containing protein.	0.999
BATDEDRAFT_653	F4NWW9_BATDJ	F4P1Z1	F4NWW9	BRCT domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.881
BATDEDRAFT_653	F4NX88_BATDJ	F4P1Z1	F4NX88	BRCT domain-containing protein.	AAA domain-containing protein.	0.999
BATDEDRAFT_653	F4NXH5_BATDJ	F4P1Z1	F4NXH5	BRCT domain-containing protein.	DNA ligase.	0.851
BATDEDRAFT_653	F4NY69_BATDJ	F4P1Z1	F4NY69	BRCT domain-containing protein.	AAA domain-containing protein.	0.999
BATDEDRAFT_653	F4NYM8_BATDJ	F4P1Z1	F4NYM8	BRCT domain-containing protein.	Uncharacterized protein.	0.865
BATDEDRAFT_653	F4NZN4_BATDJ	F4P1Z1	F4NZN4	BRCT domain-containing protein.	Uncharacterized protein.	0.582
BATDEDRAFT_653	F4P3N4_BATDJ	F4P1Z1	F4P3N4	BRCT domain-containing protein.	DNA polymerase.	0.812
BATDEDRAFT_653	F4P3X9_BATDJ	F4P1Z1	F4P3X9	BRCT domain-containing protein.	ATPase_AAA_core domain-containing protein.	0.594
BATDEDRAFT_653	F4P4N8_BATDJ	F4P1Z1	F4P4N8	BRCT domain-containing protein.	DNA_pol_E_B domain-containing protein.	0.822
BATDEDRAFT_653	F4P5H8_BATDJ	F4P1Z1	F4P5H8	BRCT domain-containing protein.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.831
BATDEDRAFT_653	F4P658_BATDJ	F4P1Z1	F4P658	BRCT domain-containing protein.	Expressed protein.	0.685
BATDEDRAFT_653	F4P6Q4_BATDJ	F4P1Z1	F4P6Q4	BRCT domain-containing protein.	Uncharacterized protein.	0.908
BATDEDRAFT_653	F4P7V0_BATDJ	F4P1Z1	F4P7V0	BRCT domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.828
BATDEDRAFT_653	F4P9K5_BATDJ	F4P1Z1	F4P9K5	BRCT domain-containing protein.	Uncharacterized protein.	0.696
BATDEDRAFT_653	F4PA52_BATDJ	F4P1Z1	F4PA52	BRCT domain-containing protein.	Uncharacterized protein.	0.929
BATDEDRAFT_653	F4PBD2_BATDJ	F4P1Z1	F4PBD2	BRCT domain-containing protein.	AAA domain-containing protein.	0.999
BATDEDRAFT_653	F4PDT6_BATDJ	F4P1Z1	F4PDT6	BRCT domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.996
BATDEDRAFT_653	FEN1	F4P1Z1	F4NRT8	BRCT domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.904