STRINGSTRING
aroE aroE aroK aroK trpC trpC KRT17295.1 KRT17295.1 KRT17296.1 KRT17296.1 KRT16711.1 KRT16711.1 KRT16473.1 KRT16473.1 hisG hisG hisD hisD hisC hisC hisB hisB hisH hisH hisA hisA hisF hisF hisI hisI KRT16081.1 KRT16081.1 KRT15460.1 KRT15460.1 KRT14778.1 KRT14778.1 KRT14337.1 KRT14337.1 KRT14339.1 KRT14339.1 KRT14340.1 KRT14340.1 aroA aroA aroC aroC KRT14347.1 KRT14347.1 KRT14047.1 KRT14047.1 KRT13933.1 KRT13933.1 KRT13805.1 KRT13805.1 KRT13523.1 KRT13523.1 trpA trpA trpB trpB trpF trpF KRT13173.1 KRT13173.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aroEAroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (167 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (260 aa)
KRT17295.1Anthranilate synthase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
KRT17296.1Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
KRT16711.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
KRT16473.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (426 aa)
hisCHistidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (346 aa)
hisBImidazoleglycerol-phosphate dehydratase; Catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (377 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (214 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
hisFImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisIphosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. (200 aa)
KRT16081.1Phenylalanine 4-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (593 aa)
KRT15460.1DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
KRT14778.1Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
KRT14337.13-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (352 aa)
KRT14339.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
KRT14340.1Cytochrome C4; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (422 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (365 aa)
KRT14347.1Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
KRT14047.1Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the inositol monophosphatase superfamily. (262 aa)
KRT13933.1Histidinol phosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
KRT13805.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
KRT13523.1Inositol oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (255 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (202 aa)
KRT13173.1Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (329 aa)
Your Current Organism:
Pedobacter ginsenosidimutans
NCBI taxonomy Id: 687842
Other names: JCM 16721, KACC 14530, P. ginsenosidimutans, Pedobacter ginsenosidimutans Yang et al. 2013, Pedobacter sp. THG-45, strain THG-45
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