STRINGSTRING
KRT14078.1 KRT14078.1 serC-2 serC-2 KRT14347.1 KRT14347.1 KRT14636.1 KRT14636.1 icmF icmF KRT14844.1 KRT14844.1 KRT14686.1 KRT14686.1 metZ metZ KRT15335.1 KRT15335.1 lysA lysA KRT15260.1 KRT15260.1 KRT15549.1 KRT15549.1 KRT15404.1 KRT15404.1 serC serC KRT15596.1 KRT15596.1 KRT15580.1 KRT15580.1 KRT15863.1 KRT15863.1 KRT15787.1 KRT15787.1 hisC hisC KRT15919.1 KRT15919.1 hemL hemL ilvA ilvA KRT16268.1 KRT16268.1 KRT16202.1 KRT16202.1 KRT16836.1 KRT16836.1 KRT16711.1 KRT16711.1 KRT18187.1 KRT18187.1 KRT17714.1 KRT17714.1 KRT16859.1 KRT16859.1 KRT17203.1 KRT17203.1 KRT17207.1 KRT17207.1 KRT17209.1 KRT17209.1 glyA glyA dxs dxs KRT18180.1 KRT18180.1 KRT17214.1 KRT17214.1 KRT13027.1 KRT13027.1 KRT13025.1 KRT13025.1 kynU kynU KRT13784.1 KRT13784.1 KRT13805.1 KRT13805.1 KRT13855.1 KRT13855.1 KRT13966.1 KRT13966.1 KRT13987.1 KRT13987.1 KRT14061.1 KRT14061.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRT14078.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
serC-23-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (357 aa)
KRT14347.1Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
KRT14636.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
icmFmethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1131 aa)
KRT14844.1L-lysine 6-transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
KRT14686.1Erythronolide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2346 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (388 aa)
KRT15335.12-oxoglutarate dehydrogenase subunit E1; Derived by automated computational analysis using gene prediction method: Protein Homology. (931 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (389 aa)
KRT15260.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
KRT15549.1Proline hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
KRT15404.1Cytochrome C biogenesis protein CcmH; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (365 aa)
KRT15596.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (396 aa)
KRT15580.12-amino-3-ketobutyrate CoA ligase; Catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
KRT15863.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
KRT15787.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
hisCHistidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (346 aa)
KRT15919.12-amino-3-ketobutyrate CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (416 aa)
KRT16268.1Acetolactate synthase catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
KRT16202.1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (794 aa)
KRT16836.1Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (376 aa)
KRT16711.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
KRT18187.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
KRT17714.1Aminotransferase class I/II; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
KRT16859.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
KRT17203.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
KRT17207.1Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
KRT17209.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1233 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (642 aa)
KRT18180.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
KRT17214.1Histidine decarboxylase; Catalyzes the formation of histamine from L-histidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
KRT13027.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
KRT13025.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (429 aa)
KRT13784.1Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
KRT13805.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
KRT13855.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
KRT13966.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
KRT13987.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
KRT14061.1Alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (233 aa)
Your Current Organism:
Pedobacter ginsenosidimutans
NCBI taxonomy Id: 687842
Other names: JCM 16721, KACC 14530, P. ginsenosidimutans, Pedobacter ginsenosidimutans Yang et al. 2013, Pedobacter sp. THG-45, strain THG-45
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