STRINGSTRING
zwf-2 zwf-2 AJG22874.1 AJG22874.1 AJG22890.1 AJG22890.1 AJG22909.1 AJG22909.1 fcl-2 fcl-2 AJG22858.1 AJG22858.1 AJG22773.1 AJG22773.1 AJG22675.1 AJG22675.1 AJG22611.1 AJG22611.1 AJG22584.1 AJG22584.1 AJG22520.1 AJG22520.1 AJG22450.1 AJG22450.1 AJG22447.1 AJG22447.1 AJG22419.1 AJG22419.1 AJG22360.1 AJG22360.1 AJG22313.1 AJG22313.1 AJG22263.1 AJG22263.1 AJG22255.1 AJG22255.1 AJG22042.1 AJG22042.1 AJG22040.1 AJG22040.1 tdh tdh AJG17949.1 AJG17949.1 pdxA pdxA zwf zwf AJG18190.1 AJG18190.1 AJG18209.1 AJG18209.1 AJG18343.1 AJG18343.1 AJG18472.1 AJG18472.1 ilvC ilvC AJG18597.1 AJG18597.1 AJG18761.1 AJG18761.1 AJG18939.1 AJG18939.1 AJG19288.1 AJG19288.1 AJG19300.1 AJG19300.1 AJG19301.1 AJG19301.1 AJG19363.1 AJG19363.1 AJG19463.1 AJG19463.1 AJG19507.1 AJG19507.1 AJG19531.1 AJG19531.1 AJG19553.1 AJG19553.1 AJG19610.1 AJG19610.1 AJG19628.1 AJG19628.1 AJG19747.1 AJG19747.1 AJG23416.1 AJG23416.1 AJG23505.1 AJG23505.1 AJG23690.1 AJG23690.1 AJG23723.1 AJG23723.1 AJG23795.1 AJG23795.1 AJG23972.1 AJG23972.1 AJG24025.1 AJG24025.1 AJG24027.1 AJG24027.1 AJG24120.1 AJG24120.1 AJG24128.1 AJG24128.1 AJG24179.1 AJG24179.1 guaB guaB dxr dxr AJG19930.1 AJG19930.1 AJG20255.1 AJG20255.1 leuB leuB mdh mdh AJG20536.1 AJG20536.1 AJG20591.1 AJG20591.1 AJG20594.1 AJG20594.1 AJG20852.1 AJG20852.1 murB murB aroE aroE hisD hisD AJG21387.1 AJG21387.1 AJG21504.1 AJG21504.1 AJG21534.1 AJG21534.1 fcl fcl AJG21792.1 AJG21792.1 AJG21962.1 AJG21962.1 AJG21973.1 AJG21973.1 AJG22961.1 AJG22961.1 AJG23161.1 AJG23161.1 AJG23209.1 AJG23209.1 AJG23229.1 AJG23229.1 AJG23238.1 AJG23238.1 AJG23261.1 AJG23261.1 AJG23401.1 AJG23401.1 AJG24206.1 AJG24206.1 AJG24260.1 AJG24260.1 gpsA gpsA AJG17740.1 AJG17740.1 AJG17663.1 AJG17663.1 AJG17606.1 AJG17606.1 AJG23328.1 AJG23328.1 AJG17929.1 AJG17929.1 AJG17948.1 AJG17948.1 AJG24277.1 AJG24277.1 AJG24293.1 AJG24293.1 AJG24296.1 AJG24296.1 AJG17871.1 AJG17871.1 AJG24404.1 AJG24404.1 fcl-3 fcl-3 AJG24480.1 AJG24480.1 AJG24482.1 AJG24482.1 AJG24556.1 AJG24556.1 AJG24559.1 AJG24559.1 AJG24564.1 AJG24564.1 AJG24623.1 AJG24623.1 AJG24875.1 AJG24875.1 AJG25041.1 AJG25041.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (484 aa)
AJG22874.1D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (403 aa)
AJG22890.16-phosphogluconate dehydrogenase, decarboxylating. (345 aa)
AJG22909.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (312 aa)
fcl-2GDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (310 aa)
AJG22858.12-hydroxy-3-oxopropionate reductase. (295 aa)
AJG22773.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
AJG22675.1Acetoacetyl-CoA reductase. (248 aa)
AJG22611.1S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (368 aa)
AJG22584.13-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (298 aa)
AJG22520.13-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (293 aa)
AJG22450.1Threonine dehydrogenase-related Zn-dependent dehydrogenase. (356 aa)
AJG22447.1MaoC-like dehydratase. (297 aa)
AJG22419.1Threonine dehydrogenase-related Zn-dependent dehydrogenase. (348 aa)
AJG22360.1Cinnamyl alcohol dehydrogenase/reductase or Alcohol dehydrogenase. (406 aa)
AJG22313.13-hydroxybutyryl-CoA dehydrogenase. (283 aa)
AJG22263.1Alcohol dehydrogenase. (302 aa)
AJG22255.13-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (298 aa)
AJG22042.1Isocitrate dehydrogenase [NADP]. (343 aa)
AJG22040.1Dihydroflavonol-4-reductase. (342 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (351 aa)
AJG17949.1D-glycerate 2-kinase. (439 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (349 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (482 aa)
AJG18190.1Putative oxidoreductase, YbiC-like; Belongs to the LDH2/MDH2 oxidoreductase family. (349 aa)
AJG18209.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
AJG18343.1UDP-glucose dehydrogenase. (457 aa)
AJG18472.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
AJG18597.13-hydroxyacyl-CoA dehydrogenase. (507 aa)
AJG18761.1D-beta-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)
AJG18939.1Acetoacetyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
AJG19288.12,3-butanediol dehydrogenase, R-alcohol forming, (R)- and (S)-acetoin-specific. (368 aa)
AJG19300.1Shikimate 5-dehydrogenase I alpha; AroD I alpha. (271 aa)
AJG19301.12-ketogluconate 6-phosphate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (325 aa)
AJG19363.1Alcohol dehydrogenase. (344 aa)
AJG19463.1Enoyl-CoA hydratase. (692 aa)
AJG19507.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
AJG19531.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (341 aa)
AJG19553.1D-beta-hydroxybutyrate dehydrogenase. (263 aa)
AJG19610.1Alcohol dehydrogenase. (382 aa)
AJG19628.1Enoyl-CoA hydratase. (693 aa)
AJG19747.1Acetoacetyl-CoA reductase. (42 aa)
AJG23416.1Isocitrate dehydrogenase [NADP]. (346 aa)
AJG23505.1Hypothetical protein. (142 aa)
AJG23690.1Putative membrane protein. (269 aa)
AJG23723.13-hydroxyacyl-CoA dehydrogenase. (323 aa)
AJG23795.12-dehydropantoate 2-reductase. (324 aa)
AJG23972.1Dihydroflavonol-4-reductase. (336 aa)
AJG24025.1Shikimate 5-dehydrogenase I alpha. (277 aa)
AJG24027.1Hypothetical protein; FIG00460847. (350 aa)
AJG24120.1Alcohol dehydrogenase. (355 aa)
AJG24128.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (319 aa)
AJG24179.1UDP-glucose dehydrogenase. (476 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (487 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (392 aa)
AJG19930.1Homoserine dehydrogenase. (436 aa)
AJG20255.1Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (355 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (322 aa)
AJG20536.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (372 aa)
AJG20591.1UDP-glucose dehydrogenase. (440 aa)
AJG20594.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (245 aa)
AJG20852.1Isocitrate dehydrogenase [NADP]. (416 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (338 aa)
aroEShikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (298 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa)
AJG21387.1D-glycerate 2-kinase. (437 aa)
AJG21504.12-dehydropantoate 2-reductase. (327 aa)
AJG21534.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa)
fclGDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (323 aa)
AJG21792.1Shikimate 5-dehydrogenase I alpha. (278 aa)
AJG21962.1Putative membrane protein. (274 aa)
AJG21973.1Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
AJG22961.1D-3-phosphoglycerate dehydrogenase. (334 aa)
AJG23161.1Enoyl-CoA hydratase. (455 aa)
AJG23209.13-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (299 aa)
AJG23229.1S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (368 aa)
AJG23238.1Hypothetical protein. (63 aa)
AJG23261.1Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (745 aa)
AJG23401.1Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (761 aa)
AJG24206.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa)
AJG24260.13-hydroxybutyryl-CoA dehydrogenase. (307 aa)
gpsAGlycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa)
AJG17740.13-hydroxybutyryl-CoA dehydrogenase. (279 aa)
AJG17663.1D-beta-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
AJG17606.1D-3-phosphoglycerate dehydrogenase. (313 aa)
AJG23328.1Malate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (364 aa)
AJG17929.1Enoyl-CoA hydratase. (808 aa)
AJG17948.1Tartrate dehydrogenase. (362 aa)
AJG24277.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
AJG24293.1D-glycerate 2-kinase. (431 aa)
AJG24296.1Tartrate dehydrogenase or Tartrate decarboxylase or D-malic enzyme. (358 aa)
AJG17871.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
AJG24404.1Alcohol dehydrogenase. (342 aa)
fcl-3GDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (329 aa)
AJG24480.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (341 aa)
AJG24482.1Alcohol dehydrogenase. (359 aa)
AJG24556.1D-mannonate oxidoreductase. (511 aa)
AJG24559.12-keto-3-deoxy-L-fuconate dehydrogenase. (251 aa)
AJG24564.1L-idonate 5-dehydrogenase. (342 aa)
AJG24623.1Enoyl-CoA hydratase. (1285 aa)
AJG24875.1MaoC-like dehydratase. (287 aa)
AJG25041.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
Your Current Organism:
Cupriavidus basilensis
NCBI taxonomy Id: 68895
Other names: C. basilensis, CCUG 49340, DSM 11853, LMG 18990, LMG 19474, LMG:18990, LMG:19474, Ralstonia basilensis, Wautersia basilensis, strain RK1
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