STRINGSTRING
AJG18440.1 AJG18440.1 pnp pnp lysS lysS pheT pheT AJG18928.1 AJG18928.1 rimO rimO AJG19777.1 AJG19777.1 ligA ligA priB priB nusA nusA ugpC ugpC rnr rnr AJG18339.1 AJG18339.1 infA infA AJG18158.1 AJG18158.1 ruvA ruvA aspS aspS AJG17855.1 AJG17855.1 rho rho rlmD rlmD infA-2 infA-2 AJG25076.1 AJG25076.1 AJG24998.1 AJG24998.1 AJG24993.1 AJG24993.1 AJG24982.1 AJG24982.1 AJG23175.1 AJG23175.1 AJG22922.1 AJG22922.1 AJG22412.1 AJG22412.1 AJG22345.1 AJG22345.1 AJG21971.1 AJG21971.1 AJG21600.1 AJG21600.1 AJG21280.1 AJG21280.1 rplB rplB rpsQ rpsQ infA-3 infA-3 AJG21142.1 AJG21142.1 AJG20959.1 AJG20959.1 recG recG AJG20851.1 AJG20851.1 metG metG AJG20450.1 AJG20450.1 AJG20270.1 AJG20270.1 rne rne recO recO efp efp AJG20179.1 AJG20179.1 AJG20178.1 AJG20178.1 AJG18374.1 AJG18374.1 AJG18383.1 AJG18383.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJG18440.1Single-stranded DNA-binding protein. (101 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (734 aa)
lysSLysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. (512 aa)
pheTPhenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (815 aa)
AJG18928.1Transcription accessory protein (S1 RNA-binding domain). (789 aa)
rimORibosomal protein S12p Asp88 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (459 aa)
AJG19777.1Putative activity regulator of membrane protease YbbK. (141 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (708 aa)
priBPrimosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (99 aa)
nusATranscription termination protein NusA; Participates in both transcription termination and antitermination. (491 aa)
ugpCGlycerol-3-phosphate ABC transporter, ATP-binding protein UgpC; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (367 aa)
rnr3'-to-5' exoribonuclease RNase R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (839 aa)
AJG18339.1SSU ribosomal protein S1p; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (564 aa)
infATranslation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (67 aa)
AJG18158.1Cold shock protein CspE. (67 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (193 aa)
aspSAspartyl-tRNA synthetase or Aspartyl-tRNA(Asn) synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (601 aa)
AJG17855.1Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (184 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (404 aa)
rlmD23S rRNA (Uracil-5-) -methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (474 aa)
infA-2Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa)
AJG25076.1Cold shock protein CspG. (67 aa)
AJG24998.1Cold shock protein CspA. (62 aa)
AJG24993.1ATP-dependent DNA ligase clustered with Ku protein, LigD. (833 aa)
AJG24982.1Hypothetical protein; FIG311564. (119 aa)
AJG23175.1Hypothetical protein; FIG00975943. (150 aa)
AJG22922.1Hypothetical protein. (135 aa)
AJG22412.1Hypothetical protein. (135 aa)
AJG22345.1Hypothetical protein. (145 aa)
AJG21971.1Hypothetical protein. (129 aa)
AJG21600.1Cold shock protein CspD. (67 aa)
AJG21280.1SSU ribosomal protein S12p (S23e); Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (89 aa)
rplBLSU ribosomal protein L2p (L8e); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa)
rpsQSSU ribosomal protein S17p (S11e); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (92 aa)
infA-3Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
AJG21142.1Maltose/maltodextrin transport ATP-binding protein MalK; Belongs to the ABC transporter superfamily. (389 aa)
AJG20959.1Exoribonuclease II. (718 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (733 aa)
AJG20851.1Cold shock protein CspD. (68 aa)
metGMethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (689 aa)
AJG20450.1Putative membrane-bound ClpP-class protease. (462 aa)
AJG20270.1Cold shock protein CspA. (65 aa)
rneRibonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1050 aa)
recODNA recombination and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (292 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (224 aa)
AJG20179.1Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC; Belongs to the ABC transporter superfamily. (366 aa)
AJG20178.1Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC; Belongs to the ABC transporter superfamily. (368 aa)
AJG18374.1DNA polymerase III alpha subunit. (1170 aa)
AJG18383.1Cytoplasmic axial filament protein CafA and Ribonuclease G. (488 aa)
Your Current Organism:
Cupriavidus basilensis
NCBI taxonomy Id: 68895
Other names: C. basilensis, CCUG 49340, DSM 11853, LMG 18990, LMG 19474, LMG:18990, LMG:19474, Ralstonia basilensis, Wautersia basilensis, strain RK1
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