STRINGSTRING
AJG17559.1 AJG17559.1 AJG17591.1 AJG17591.1 AJG17593.1 AJG17593.1 AJG17605.1 AJG17605.1 adc adc AJG17685.1 AJG17685.1 AJG17687.1 AJG17687.1 AJG17732.1 AJG17732.1 AJG17733.1 AJG17733.1 sucC sucC sucD sucD AJG18190.1 AJG18190.1 ackA ackA AJG18196.1 AJG18196.1 mgsA mgsA AJG18688.1 AJG18688.1 accA accA AJG18891.1 AJG18891.1 AJG18938.1 AJG18938.1 AJG18944.1 AJG18944.1 AJG19453.1 AJG19453.1 AJG19460.1 AJG19460.1 AJG19462.1 AJG19462.1 AJG19515.1 AJG19515.1 AJG19516.1 AJG19516.1 AJG19538.1 AJG19538.1 AJG19552.1 AJG19552.1 AJG19626.1 AJG19626.1 prpB prpB AJG19664.1 AJG19664.1 AJG19665.1 AJG19665.1 AJG19666.1 AJG19666.1 AJG20005.1 AJG20005.1 AJG20132.1 AJG20132.1 acsA acsA accD accD AJG20311.1 AJG20311.1 AJG20313.1 AJG20313.1 AJG20387.1 AJG20387.1 AJG20666.1 AJG20666.1 AJG20967.1 AJG20967.1 AJG20968.1 AJG20968.1 AJG21076.1 AJG21076.1 AJG21098.1 AJG21098.1 AJG21710.1 AJG21710.1 AJG21795.1 AJG21795.1 AJG21798.1 AJG21798.1 AJG21991.1 AJG21991.1 AJG22140.1 AJG22140.1 AJG22153.1 AJG22153.1 AJG22254.1 AJG22254.1 AJG22312.1 AJG22312.1 AJG22428.1 AJG22428.1 AJG22429.1 AJG22429.1 AJG22445.1 AJG22445.1 AJG22496.1 AJG22496.1 AJG22505.1 AJG22505.1 AJG22518.1 AJG22518.1 AJG22531.1 AJG22531.1 AJG22546.1 AJG22546.1 AJG22583.1 AJG22583.1 AJG22676.1 AJG22676.1 AJG22681.1 AJG22681.1 AJG22691.1 AJG22691.1 AJG22709.1 AJG22709.1 AJG22907.1 AJG22907.1 AJG22923.1 AJG22923.1 AJG23100.1 AJG23100.1 AJG23103.1 AJG23103.1 AJG23170.1 AJG23170.1 AJG23174.1 AJG23174.1 AJG23210.1 AJG23210.1 AJG23492.1 AJG23492.1 sucC-2 sucC-2 sucD-2 sucD-2 AJG23904.1 AJG23904.1 AJG23910.1 AJG23910.1 AJG23913.1 AJG23913.1 AJG23915.1 AJG23915.1 AJG24284.1 AJG24284.1 AJG24395.1 AJG24395.1 AJG24430.1 AJG24430.1 AJG24543.1 AJG24543.1 AJG24820.1 AJG24820.1 AJG24825.1 AJG24825.1 AJG24984.1 AJG24984.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJG17559.1Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (294 aa)
AJG17591.13-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
AJG17593.1Isovaleryl-CoA dehydrogenase. (376 aa)
AJG17605.1Methylcrotonyl-CoA carboxylase biotin-containing subunit. (262 aa)
adcAcetoacetate decarboxylase; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family. (246 aa)
AJG17685.1Protein acetyltransferase. (703 aa)
AJG17687.1Biotin carboxyl carrier protein. (70 aa)
AJG17732.1Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
AJG17733.1Methylmalonate-semialdehyde dehydrogenase. (505 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
AJG18190.1Putative oxidoreductase, YbiC-like; Belongs to the LDH2/MDH2 oxidoreductase family. (349 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (408 aa)
AJG18196.1Phosphate acetyltransferase. (363 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (131 aa)
AJG18688.1Acetyl-coenzyme A synthetase. (577 aa)
accAAcetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (323 aa)
AJG18891.1Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (594 aa)
AJG18938.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
AJG18944.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
AJG19453.1Alcohol dehydrogenase. (327 aa)
AJG19460.1Enoyl-CoA hydratase. (262 aa)
AJG19462.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
AJG19515.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
AJG19516.1Alcohol dehydrogenase. (328 aa)
AJG19538.1Acetyl-coenzyme A synthetase. (588 aa)
AJG19552.1Acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit. (663 aa)
AJG19626.13-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (304 aa)
AJG19664.12-methylcitrate synthase; Belongs to the citrate synthase family. (385 aa)
AJG19665.12-methylcitrate dehydratase FeS dependent. (865 aa)
AJG19666.12-methylaconitate cis-trans isomerase. (396 aa)
AJG20005.1Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. (478 aa)
AJG20132.1Propionate--CoA ligase. (630 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
accDAcetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
AJG20311.12-methylcitrate synthase; Belongs to the citrate synthase family. (387 aa)
AJG20313.12-methylcitrate dehydratase. (468 aa)
AJG20387.1Acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (548 aa)
AJG20666.1Malonyl-CoA decarboxylase. (482 aa)
AJG20967.1Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
AJG20968.1Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa)
AJG21076.1Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
AJG21098.1Alcohol dehydrogenase. (329 aa)
AJG21710.1Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (420 aa)
AJG21795.1Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (466 aa)
AJG21798.1Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit. (729 aa)
AJG21991.1Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase. (549 aa)
AJG22140.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (689 aa)
AJG22153.1Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (861 aa)
AJG22254.1Methylmalonate-semialdehyde dehydrogenase. (507 aa)
AJG22312.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
AJG22428.1Acetyl-coenzyme A synthetase. (646 aa)
AJG22429.1Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (276 aa)
AJG22445.1Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
AJG22496.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (364 aa)
AJG22505.1Penicillin-binding protein. (419 aa)
AJG22518.1Methylmalonate-semialdehyde dehydrogenase. (501 aa)
AJG22531.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
AJG22546.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
AJG22583.1Methylmalonate-semialdehyde dehydrogenase. (507 aa)
AJG22676.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
AJG22681.1Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (589 aa)
AJG22691.1Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (424 aa)
AJG22709.1Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
AJG22907.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
AJG22923.1Acetyl-CoA acetyltransferase. (388 aa)
AJG23100.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (701 aa)
AJG23103.1Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
AJG23170.1Hypothetical protein; FIG00663289. (716 aa)
AJG23174.1Acetyl-CoA acetyltransferase. (378 aa)
AJG23210.1Methylmalonate-semialdehyde dehydrogenase. (506 aa)
AJG23492.1Enoyl-CoA hydratase. (245 aa)
sucC-2Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (410 aa)
sucD-2Succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
AJG23904.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
AJG23910.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
AJG23913.1Enoyl-CoA hydratase. (272 aa)
AJG23915.1Enoyl-CoA hydratase. (296 aa)
AJG24284.1Phosphate acetyltransferase. (346 aa)
AJG24395.1Methylmalonate-semialdehyde dehydrogenase. (506 aa)
AJG24430.1Dihydrolipoamide dehydrogenase. (484 aa)
AJG24543.1Enoyl-CoA hydratase. (251 aa)
AJG24820.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (718 aa)
AJG24825.13-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
AJG24984.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (706 aa)
Your Current Organism:
Cupriavidus basilensis
NCBI taxonomy Id: 68895
Other names: C. basilensis, CCUG 49340, DSM 11853, LMG 18990, LMG 19474, LMG:18990, LMG:19474, Ralstonia basilensis, Wautersia basilensis, strain RK1
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