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GLE_2423 GLE_2423 GLE_2482 GLE_2482 GLE_1982 GLE_1982 GLE_1971 GLE_1971 GLE_1879 GLE_1879 GLE_1765 GLE_1765 gloB gloB GLE_1415 GLE_1415 GLE_1373 GLE_1373 pckA pckA GLE_1016 GLE_1016 pyk pyk cat2 cat2 GLE_0907 GLE_0907 GLE_0853 GLE_0853 leuA leuA accB accB accC accC GLE_0677 GLE_0677 aceF aceF GLE_0670 GLE_0670 GLE_0564 GLE_0564 GLE_0513 GLE_0513 aceB aceB acsA acsA GLE_5085 GLE_5085 GLE_5043 GLE_5043 GLE_5019 GLE_5019 GLE_5006 GLE_5006 GLE_4884 GLE_4884 ppc ppc maeB maeB aceE aceE GLE_4730 GLE_4730 GLE_4574 GLE_4574 GLE_4326 GLE_4326 GLE_4321 GLE_4321 GLE_4319 GLE_4319 pdhB pdhB pdhA pdhA GLE_4146 GLE_4146 gloA gloA GLE_3969 GLE_3969 acyP acyP mdh mdh GLE_3707 GLE_3707 GLE_3633 GLE_3633 GLE_3527 GLE_3527 accA accA GLE_3068 GLE_3068 ppsA ppsA lpdA lpdA fumC fumC GLE_2038 GLE_2038 GLE_2141 GLE_2141 accD accD GLE_2401 GLE_2401 mqo mqo
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLE_2423Metallo-beta-lactamase superfamily protein. (324 aa)
GLE_2482Oxidoreductase, FAD binding. (468 aa)
GLE_1982Glyoxalase. (147 aa)
GLE_1971acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
GLE_1879Dyp-type peroxidase family protein. (327 aa)
GLE_1765Piperideine-6-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (260 aa)
GLE_1415Glyoxalase/bleomycin resistance protein/dioxygenase. (141 aa)
GLE_1373Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein. (116 aa)
pckAPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (601 aa)
GLE_1016Glyoxalase/bleomycin resistance protein/dioxygenase. (119 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (488 aa)
cat24-hydroxybutyrate coenzyme A transferase. (701 aa)
GLE_0907Glyoxalase. (156 aa)
GLE_0853Glyoxalase/bleomycin resistance protein/dioxygenase. (152 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (538 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (161 aa)
accCacetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa)
GLE_0677Dihydrolipoyl dehydrogenase. (606 aa)
aceFDihydrolipoyllysine-residue acetyltransferase. (474 aa)
GLE_0670Glyoxalase/bleomycin resistance protein/dioxygenase. (251 aa)
GLE_0564Glyoxalase family protein. (433 aa)
GLE_0513Glyoxalase family protein. (139 aa)
aceBMalate synthase A. (544 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa)
GLE_50853-demethylubiquinone-9 3-methyltransferase domain protein. (150 aa)
GLE_5043acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)
GLE_5019Hypothetical protein. (425 aa)
GLE_5006Aldehyde dehydrogenase (NAD) family protein; Belongs to the aldehyde dehydrogenase family. (475 aa)
GLE_4884Metallo-beta-lactamase family protein. (268 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (920 aa)
maeBNADP-dependent malic enzyme. (770 aa)
aceEPyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (901 aa)
GLE_4730Glyoxalase. (139 aa)
GLE_4574Glyoxylase family protein. (128 aa)
GLE_4326Metallo-beta-lactamase superfamily protein. (315 aa)
GLE_4321Hypothetical protein. (127 aa)
GLE_4319Branched-chain alpha-keto acid dehydrogenase subunit E2. (455 aa)
pdhBPyruvate dehydrogenase E1 component, beta subunit. (343 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (356 aa)
GLE_4146D-lactate dehydrogenase. (464 aa)
gloALactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (176 aa)
GLE_3969Glyoxalase/bleomycin resistance protein/dioxygenase. (135 aa)
acyPAcylphosphatase. (89 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
GLE_3707Hypothetical protein. (126 aa)
GLE_3633Hypothetical protein. (74 aa)
GLE_3527Metallo-beta-lactamase superfamily protein. (296 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
GLE_3068Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (504 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (795 aa)
lpdADihydrolipoyl dehydrogenase. (474 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (489 aa)
GLE_2038Glyoxalase/bleomycin resistance protein/dioxygenase. (141 aa)
GLE_2141D-isomer specific 2-hydroxyacid dehydrogenase. (337 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (295 aa)
GLE_2401Metallo-beta-lactamase family protein. (298 aa)
mqoMalate:quinone oxidoreductase. (564 aa)
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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