STRINGSTRING
TK0033 TK0033 TK0319 TK0319 TK0353 TK0353 TK0355 TK0355 TK0356 TK0356 TK0357 TK0357 TK0436 TK0436 cas2 cas2 TK0446 TK0446 TK0447 TK0447 TK0448 TK0448 TK0449 TK0449 TK0450 TK0450 TK0451 TK0451 TK0452 TK0452 TK0453 TK0453 TK0454 TK0454 cas1 cas1 vapC-4 vapC-4 TK0457 TK0457 TK0458 TK0458 TK0459 TK0459 TK0460 TK0460 TK0461 TK0461 TK0462 TK0462 TK0463 TK0463 TK0464 TK0464 TK0466 TK0466 TK0650 TK0650 TK0806 TK0806 TK0807 TK0807 TK0810 TK0810 TK0827 TK0827 TK1033 TK1033 TK1034 TK1034 TK1035 TK1035 TK1036 TK1036 TK1037 TK1037 TK1162 TK1162 TK1163 TK1163 TK1164 TK1164 TK1165 TK1165 TK1184 TK1184 TK1185 TK1185 TK1295 TK1295 TK1300 TK1300 Tko1797 Tko1797 TK1549 TK1549 TK1580 TK1580 TK1718 TK1718 TK1804 TK1804 TK1909 TK1909 TK1910 TK1910 TK1911 TK1911 TK1912 TK1912 TK2114 TK2114 TK2166 TK2166 TK2167 TK2167 TK2232 TK2232 TK2233 TK2233 TK2234 TK2234 TK2241 TK2241 TK2242 TK2242 TK2243 TK2243 TK2245 TK2245 TK2247 TK2247 TK2253 TK2253
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TK0033Hypothetical protein, conserved, containing leucine zipper motif. (351 aa)
TK0319Pterin-binding protein. (510 aa)
TK0353Hypothetical protein. (170 aa)
TK0355ABC-type multidrug transport system, ATPase component. (309 aa)
TK0356Hypothetical membrane protein, conserved. (708 aa)
TK0357Hypothetical membrane protein, conserved. (308 aa)
TK0436ABC-type transporter, ATPase component, fused to acetyltransferase domain. (633 aa)
cas2Hypothetical protein, conserved, DUF196 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (85 aa)
TK0446Hypothetical protein, conserved. (233 aa)
TK0447Hypothetical protein, conserved, RAMP superfamily; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). (257 aa)
TK0448Predicted transcription regulator, containing DNA-binding HTH domain. (225 aa)
TK0449Metal-dependent phosphohydrolase, HD superfamily. (220 aa)
TK0450DEAD/DEAH box helicase. (533 aa)
TK0451Hypothetical protein, conserved. (399 aa)
TK0452Hypothetical protein, conserved, RAMP superfamily. (247 aa)
TK0453Hypothetical protein, conserved, DUF73 family, insertion. (400 aa)
TK0454Hypothetical protein, conserved. (121 aa)
cas1Hypothetical protein, conserved, DUF48 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (326 aa)
vapC-4Predicted nucleic acid-binding protein, containing PIN domain; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (137 aa)
TK0457Transcription regulator, SpoVT/AbrB family. (75 aa)
TK0458Predicted exonuclease, RecB family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (170 aa)
TK0459Archaeal ATPase. (369 aa)
TK0460DEAD/DEAH box helicase, fused to N-terminal HD domain. (740 aa)
TK0461Hypothetical protein, conserved, RAMP superfamily. (210 aa)
TK0462Hypothetical protein, conserved. (358 aa)
TK0463Hypothetical protein, conserved. (490 aa)
TK0464Hypothetical protein, conserved, RAMP superfamily; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). (263 aa)
TK0466Hypothetical protein, conserved. (440 aa)
TK0650Rubrerythrin-related protein. (174 aa)
TK0806Putative membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase. (452 aa)
TK0807Hypothetical protein, conserved. (383 aa)
TK0810Oligosaccharyl transferase, STT3 subunit. (1000 aa)
TK0827Predicted permease, major facilitator superfamily. (390 aa)
TK1033Predicted metalloprotease, containing Jab1/MPN domain. (132 aa)
TK1034Predicted restriction endonuclease. (296 aa)
TK1035Predicted glutamine amidotransferase, class II. (267 aa)
TK1036Hypothetical protein, conserved, containing CBS domains. (136 aa)
TK1037Metallophosphoesterase, calcineurin superfamily. (502 aa)
TK1162Hypothetical membrane protein, conserved, DUF20 family. (330 aa)
TK1163Hypothetical protein, conserved. (159 aa)
TK1164Predicted endopeptidase IV, S49 family. (334 aa)
TK1165Predicted AP endonuclease. (268 aa)
TK1184Hypothetical protein, conserved. (100 aa)
TK1185Predicted nucleic acid-binding protein, containing PIN domain. (164 aa)
TK1295Predicted thiol protease. (1103 aa)
TK1300Hypothetical membrane protein, conserved. (482 aa)
Tko1797Phosphomannomutase-related protein. (236 aa)
TK1549Predicetd ATPase. (193 aa)
TK1580Hypothetical protein, conserved, UPF0153 family. (169 aa)
TK1718Oligosaccharyl transferase, STT3 subunit. (766 aa)
TK1804ABC-type dipeptide/oligopeptide transport system, probable periplasmic component. (815 aa)
TK1909Dolichol-phosphate mannosyltransferase, fused to membrane-bound GtrA-like domain. (352 aa)
TK1910ATPase, RecA superfamily. (237 aa)
TK1911Hypothetical protein, conserved. (147 aa)
TK1912Aminopeptidase, family M28, containing PA domain. (561 aa)
TK2114Hypothetical protein, conserved. (310 aa)
TK2166ArgE/DapE-related deacylase. (372 aa)
TK21673'-phosphoadenosine 5'-phosphosulfate reductase, fused to N-terminal uncharacterized archaeal domain. (435 aa)
TK2232Hydrolase, metallo-beta-lactamase superfamily. (211 aa)
TK2233Hypothetical protein, conserved, DUF437 family. (121 aa)
TK2234Hypothetical membrane protein, conserved. (239 aa)
TK2241SAM-dependent methyltransferase, UbiE/COQ5 family. (228 aa)
TK2242GHMP kinase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (318 aa)
TK2243Hypothetical protein, conserved, DUF1464 family. (383 aa)
TK2245Transcription regulator, SpoVT/AbrB family, containing PhoU domain. (304 aa)
TK2247Predicted permease, major facilitator superfamily. (391 aa)
TK2253Hypothetical protein, conserved, RAMP superfamily; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). (249 aa)
Your Current Organism:
Thermococcus kodakarensis
NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1
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