STRINGSTRING
cas2 cas2 TK0446 TK0446 TK0447 TK0447 TK0448 TK0448 TK0449 TK0449 TK0450 TK0450 TK0451 TK0451 TK0452 TK0452 TK0453 TK0453 TK0454 TK0454 cas1 cas1 TK0458 TK0458 TK0460 TK0460 TK0461 TK0461 TK0462 TK0462 TK0463 TK0463 TK0464 TK0464 TK2253 TK2253
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cas2Hypothetical protein, conserved, DUF196 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (85 aa)
TK0446Hypothetical protein, conserved. (233 aa)
TK0447Hypothetical protein, conserved, RAMP superfamily; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). (257 aa)
TK0448Predicted transcription regulator, containing DNA-binding HTH domain. (225 aa)
TK0449Metal-dependent phosphohydrolase, HD superfamily. (220 aa)
TK0450DEAD/DEAH box helicase. (533 aa)
TK0451Hypothetical protein, conserved. (399 aa)
TK0452Hypothetical protein, conserved, RAMP superfamily. (247 aa)
TK0453Hypothetical protein, conserved, DUF73 family, insertion. (400 aa)
TK0454Hypothetical protein, conserved. (121 aa)
cas1Hypothetical protein, conserved, DUF48 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (326 aa)
TK0458Predicted exonuclease, RecB family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (170 aa)
TK0460DEAD/DEAH box helicase, fused to N-terminal HD domain. (740 aa)
TK0461Hypothetical protein, conserved, RAMP superfamily. (210 aa)
TK0462Hypothetical protein, conserved. (358 aa)
TK0463Hypothetical protein, conserved. (490 aa)
TK0464Hypothetical protein, conserved, RAMP superfamily; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). (263 aa)
TK2253Hypothetical protein, conserved, RAMP superfamily; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). (249 aa)
Your Current Organism:
Thermococcus kodakarensis
NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1
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