STRINGSTRING
TK1984 TK1984 TK2007 TK2007 TK2021 TK2021 TK2052 TK2052 eno eno TK2113 TK2113 TK2115 TK2115 TK2118 TK2118 tpiA tpiA TK2132 TK2132 TK2137 TK2137 cpkA cpkA TK2169 TK2169 TK2170 TK2170 glmM glmM pyrB pyrB TK2250 TK2250 TK2275 TK2275 pyrF pyrF pth pth TK2301 TK2301 TK0327 TK0327 TK0332 TK0332 TK0349 TK0349 deoA deoA thiI thiI TK0425 TK0425 ribA ribA purC-2 purC-2 thiC thiC thi4 thi4 TK0435 TK0435 TK0450 TK0450 TK0460 TK0460 TK0475 TK0475 aspS aspS TK0499 TK0499 TK0502 TK0502 TK0508 TK0508 pyk pyk TK0515 TK0515 TK0537 TK0537 TK0544 TK0544 TK0561 TK0561 TK0631 TK0631 TK0655 TK0655 gyaR gyaR TK0698 TK0698 TK0699 TK0699 TK0700 TK0700 top6B top6B TK0816 TK0816 TK0834 TK0834 purK purK cobQ cobQ rpl21e rpl21e TK0915 TK0915 TK0950 TK0950 TK0952 TK0952 rpl37e rpl37e metG metG TK1065 TK1065 rps7 rps7 rps12 rps12 rpl30e rpl30e rps27e rps27e TK1108 TK1108 TK1124 TK1124 TK1129 TK1129 serS serS pgk pgk TK1165 TK1165 rps8e rps8e pyrG pyrG rps15 rps15 rps3ae rps3ae TK1257 TK1257 TK1259 TK1259 TK1260 TK1260 valS valS TK1278 TK1278 rps28e rps28e rpl7ae rpl7ae rpl39e rpl39e rpl31e rpl31e eif6 eif6 TK1331 TK1331 gcvPB gcvPB gcvPA gcvPA glpK glpK Tko1797 Tko1797 pckG pckG gltX gltX dcd dcd rpl10 rpl10 rpl1 rpl1 rpiA rpiA TK0005 TK0005 TK0026 TK0026 ahcY ahcY ef1b ef1b TK0168 TK0168 TK0173 TK0173 guaAA guaAA guaAB guaAB purD purD purT purT purM purM purC purC pdxT pdxT TK0251 TK0251 trpD trpD trpA trpA aroC aroC rps10 rps10 TK1445 TK1445 TK1448 TK1448 rpl15e rpl15e TK1473 TK1473 mvk mvk TK1479 TK1479 TK1482 TK1482 TK1487 TK1487 rps2 rps2 TK1497 TK1497 rps9 rps9 rpl13 rpl13 rpl18e rpl18e rps11 rps11 rps13 rps13 rpl14e rpl14e rpl15 rpl15 rpl30 rpl30 rps5 rps5 rpl18 rpl18 rpl19e rpl19e rpl32e rpl32e rpl6 rpl6 rps8 rps8 rps14 rps14 rpl5 rpl5 rps4e rps4e rpl24 rpl24 rpl14 rpl14 rps17 rps17 rps3 rps3 rpl22 rpl22 rps19 rps19 rpl2 rpl2 rpl23 rpl23 rpl4 rpl4 rpl3 rpl3 rpl10e rpl10e TK1556 TK1556 speH speH eif2b eif2b TK1640 TK1640 TK1652 TK1652 TK1676 TK1676 ppa ppa TK1716 TK1716 TK1738 TK1738 ileS ileS TK1777 TK1777 TK1821 TK1821 galK galK pcp pcp TK1841 TK1841 TK1865 TK1865 mtnP mtnP engB engB TK1955 TK1955 TK1970 TK1970 TK1981 TK1981
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TK1984Pyruvate:ferredoxin oxidoreductase, beta subunit. (331 aa)
TK2007ATPase involved in chromosome partitioning, ParA/MinD family, Mrp homolog; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (248 aa)
TK2021ATPase involved in chromosome partitioning, ParA/MinD family, Mrp homolog; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (295 aa)
TK2052Predicted transcription regulator, Lrp/AsnC family. (75 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
TK2113Hypothetical protein, conserved. (306 aa)
TK2115Molybdopterin converting factor, subunit 2. (141 aa)
TK2118Molybdopterin converting factor, subunit 1. (88 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (226 aa)
TK2132Fuculose-1-phosphate aldolase. (184 aa)
TK2137ATPase involved in chromosome partitioning, ParA/MinD family. (276 aa)
cpkACarbamate kinase-like carbamoyl phosphate synthetase. (315 aa)
TK2169Zinc-dependent protease, TldD/PmbA family. (455 aa)
TK2170Zinc-dependent protease, TldD/PmbA family. (429 aa)
glmMPhosphohexomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity). Does not display phosphoglucomutase (PGM) or phosphomannomutase (PMM) activities. (449 aa)
pyrBAspartate carbamoyltransferase, catalytic subunit. (310 aa)
TK2250Serine/threonine protein kinase, RIO1 family. (311 aa)
TK2275RNA-binding protein, containing PUA domain. (172 aa)
pyrFOrotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (213 aa)
pthpeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (118 aa)
TK2301Hydrolase, HAD superfamily; Catalyzes the dephosphorylation of 2-phosphoglycolate. (239 aa)
TK0327Phosphohydrolase, PHP family. (218 aa)
TK0332Allophanate hydrolase, subunit 2. (331 aa)
TK0349ATPase involved in chromosome partitioning, ParA/MinD family. (259 aa)
deoAThymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP, dCMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. (503 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (381 aa)
TK0425Riboflavin synthase, alpha subunit. (184 aa)
ribARiboflavin biosynthesis protein RibA; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (386 aa)
purC-2Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family. (219 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (428 aa)
thi4Thiazole biosynthetic enzyme Thi4; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (251 aa)
TK0435Phosphomethylpyrimidine kinase, fused to C-terminal uncharacterized domain. (431 aa)
TK0450DEAD/DEAH box helicase. (533 aa)
TK0460DEAD/DEAH box helicase, fused to N-terminal HD domain. (740 aa)
TK0475Bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase. (406 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Is specific for tRNA(Asp) since it aspartylates tRNA(Asn) 3 orders of magnitude less efficiently than tRNA(Asp); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. (438 aa)
TK0499Zinc-dependent protease, TldD/PmbA family. (441 aa)
TK0502Zinc-dependent protease, TldD/PmbA family. (455 aa)
TK0508Predicted transcription regulator, Lrp/AsnC family. (160 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
TK0515Hypothetical protein, conserved, DUF190 family. (126 aa)
TK0537Peroxiredoxin, AhpC/TSA family; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (216 aa)
TK0544Molybdenum cofactor biosynthesis protein B. (170 aa)
TK0561Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (454 aa)
TK0631Chemotaxis protein methyltransferase. (279 aa)
TK0655Predicted site-specific integrase/resolvase. (209 aa)
gyaRGlyoxylate reductase. (333 aa)
TK0698Zinc-dependent protease, TldD/PmbA family. (440 aa)
TK0699Zinc-dependent protease, TldD/PmbA family. (473 aa)
TK0700Nucleotide pyrophosphohydrolase. (97 aa)
top6BType II DNA topoisomerase VI, subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (567 aa)
TK08162-oxoacid:ferredoxin oxidoreductase, beta subunit. (294 aa)
TK0834Transcription regulator, Lrp/AsnC family. (192 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (381 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity); Belongs to the CobB/CobQ family. CobQ subfamily. (483 aa)
rpl21eLSU ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (98 aa)
TK0915ATPase involved in chromosome partitioning, ParA/MinD family. (248 aa)
TK0950Asparagine synthase (glutamine-hydrolyzing). (483 aa)
TK0952ATPase involved in chromosome partitioning, ParA/MinD family. (245 aa)
rpl37eLSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (63 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (741 aa)
TK1065Molybdopterin converting factor, subunit 1. (82 aa)
rps7SSU ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (215 aa)
rps12SSU ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
rpl30eLSU ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (102 aa)
rps27eSSU ribosomal protein S27E. (65 aa)
TK1108Phosphohexomutase; Catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate, and the interconversion of mannose 1-phosphate and mannose 6-phosphate. Also displays low activity with deoxyribose 1- phosphate and glucosamine 1-phosphate; Belongs to the phosphohexose mutase family. (456 aa)
TK11242-oxoacid:ferredoxin oxidoreductases, beta subunit. (281 aa)
TK11292-oxoacid:ferredoxin oxidoreductases, beta subunit. (288 aa)
serSSeryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (455 aa)
pgk3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (411 aa)
TK1165Predicted AP endonuclease. (268 aa)
rps8eSSU ribosomal protein S8E. (130 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (533 aa)
rps15SSU ribosomal protein S15P. (151 aa)
rps3aeSSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (200 aa)
TK1257RNA-binding protein, containing THUMP domain. (355 aa)
TK1259Predicted transcription regulator, Lrp/AsnC family. (150 aa)
TK1260Nucleotide pyrophosphohydrolase. (94 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (888 aa)
TK1278Double-stranded DNA-binding protein; Belongs to the PDCD5 family. (112 aa)
rps28eSSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (70 aa)
rpl7aeLSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (125 aa)
rpl39eLSU ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa)
rpl31eLSU ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family. (90 aa)
eif6Translation initiation factor eIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (229 aa)
TK1331Predicted transcription regulator, Lrp/AsnC family. (80 aa)
gcvPBGlycine cleavage system protein P, subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (502 aa)
gcvPAGlycine cleavage system protein P, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (451 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. Can utilize other nucleoside triphosphates (GTP, CTP, UTP AND ITP) as a phosphoryl donor; Belongs to the FGGY kinase family. (497 aa)
Tko1797Phosphomannomutase-related protein. (236 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (623 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (573 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (155 aa)
rpl10LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (340 aa)
rpl1LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (216 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (229 aa)
TK0005CoA-binding protein. (142 aa)
TK0026Probable phosphoglycolate phosphatase, HAD superfamily. (217 aa)
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (421 aa)
ef1bTranslation elongation factor EF-1, beta subunit; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (91 aa)
TK0168Predicted transcription regulator, Lrp/AsnC family. (77 aa)
TK0173Hypothetical protein, conserved, DUF77 family. (100 aa)
guaAAGMP synthase, glutamine amidotransferase component; Catalyzes the synthesis of GMP from XMP. (188 aa)
guaABGMP synthase, PP-loop-ATPase component; Catalyzes the synthesis of GMP from XMP. (307 aa)
purDPhosphoribosylamine-glycine ligase. (431 aa)
purTFormate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (429 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (334 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (235 aa)
pdxTPyridoxine biosynthesis amidotransferase, SNO family; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (197 aa)
TK0251Predicted hydrolase, HAD superfamily. (242 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (325 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (251 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (355 aa)
rps10SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
TK1445Aspartokinase. (366 aa)
TK14485,10-methylenetetrahydrofolate reductase. (352 aa)
rpl15eLSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (194 aa)
TK1473Amino acid kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (262 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (337 aa)
TK1479Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (277 aa)
TK1482Purine-nucleoside phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. (267 aa)
TK1487Predicted transcription regulator, Lrp/AsnC family. (79 aa)
rps2SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (201 aa)
TK1497Enolase-related protein. (341 aa)
rps9SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (135 aa)
rpl13LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
rpl18eLSU ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa)
rps11SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (140 aa)
rps13SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (149 aa)
rpl14eLSU ribosomal protein L14E; Belongs to the eukaryotic ribosomal protein eL14 family. (83 aa)
rpl15LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa)
rpl30LSU ribosomal protein L30P. (155 aa)
rps5SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (235 aa)
rpl18LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (201 aa)
rpl19eLSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa)
rpl32eLSU ribosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (126 aa)
rpl6LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa)
rps8SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rps14SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (56 aa)
rpl5LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (183 aa)
rps4eSSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa)
rpl24LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (121 aa)
rpl14LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa)
rps17SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (114 aa)
rps3SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (209 aa)
rpl22LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (156 aa)
rps19SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (133 aa)
rpl2LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (239 aa)
rpl23LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa)
rpl4LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (255 aa)
rpl3LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (346 aa)
rpl10eLSU ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family. (182 aa)
TK1556ATPase, PP-loop superfamily. (304 aa)
speHS-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (143 aa)
eif2bTranslation initiation factor eIF-2, beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (142 aa)
TK1640Nucleotide pyrophosphohydrolase. (106 aa)
TK1652Predicted thioesterase. (140 aa)
TK1676Nicotinate-nucleotide pyrophosphorylase. (390 aa)
ppaInorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (178 aa)
TK1716Cytidylyltransferase. (229 aa)
TK17382'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (184 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1065 aa)
TK1777Phosphopentomutase; Catalyzes the conversion of deoxyribose 1-phosphate to deoxyribose 5-phosphate. Shows also weak activity with glucose 1- phosphate and mannose 1-phosphate. Could be involved in pentose biosynthesis. (450 aa)
TK1821ATPase, PP-loop superfamily. (323 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (350 aa)
pcpPyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family. (206 aa)
TK1841Predicted site-specific integrase-resolvase. (202 aa)
TK1865Predicted AP endonuclease. (271 aa)
mtnPPurine-nucleoside phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (257 aa)
engBProbable GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation. (183 aa)
TK1955Predicted transcription regulator, Lrp/AsnC family. (154 aa)
TK1970Probable tRNA/rRNA methyltransferase, SpoU family. (235 aa)
TK19812-oxoisovalerate:ferredoxin oxidoreductase, beta subunit. (311 aa)
Your Current Organism:
Thermococcus kodakarensis
NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1
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