STRINGSTRING
TK0617 TK0617 tfe tfe TK1945 TK1945 cdc6 cdc6 TK1636 TK1636 TK1581 TK1581 TK1199 TK1199 TK1190 TK1190 nop10 nop10 nep1 nep1 TK0800 TK0800 TK2286 TK2286 TK2275 TK2275
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TK0617U3 snoRNP component, archaeal imp4 homolog, containing Brix domain; Probably involved in the biogenesis of the ribosome. (208 aa)
tfeTranscription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] (185 aa)
TK1945Predicted nucleic acid-binding protein, containing PIN domain. (140 aa)
cdc6Cell division control protein 6 homolog; Involved in regulation of DNA replication. (415 aa)
TK1636Predicted exosome subunit, UPF0023 family. (236 aa)
TK1581Hypothetical protein, conserved, UPF0113 family. (169 aa)
TK1199TBP-interacting protein Tip49 homolog. (440 aa)
TK1190Predicted GTPase, containing NOG1 domain. (358 aa)
nop10RNA-binding protein, Nop10p family; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (59 aa)
nep1Ribosome biogenesis protein Nep1p homolog, suppressor Mra1 family; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (220 aa)
TK0800RNA-binding protein, containing KH domain. (238 aa)
TK2286snoRNP component, Gar1 homolog. (115 aa)
TK2275RNA-binding protein, containing PUA domain. (172 aa)
Your Current Organism:
Thermococcus kodakarensis
NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.