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| | rps10 | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | trmBL2 | Probable transcription regulator, DUF118 helix-turn-helix family; An abundant chromosomal protein that seems to be involved in both genome architecture and transcription repression. Incubation with DNA in vitro gives fibrous structures 14.2 +/- 2.1 nm in thickness (naked DNA is 1.83 +/- 0.37 nm); does not significantly compact DNA. Binds to both coding and non-coding regions; binding within gene promoters correlates with decreased transcript levels, while binding within coding regions does not. (264 aa) |
| | albA | Archaeal chromatin protein, Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity). Incubation with DNA in vitro gives fibrous structures 10.3 +/- 1.1 nm in thickness (naked DNA is 1.83 +/- 0.37 nm). This protein does not significantly compact DNA ; Belongs to the histone-like Alba family. (91 aa) |
| | rpl37ae | LSU ribosomal protein L37AE. (86 aa) |
| | TK0617 | U3 snoRNP component, archaeal imp4 homolog, containing Brix domain; Probably involved in the biogenesis of the ribosome. (208 aa) |
| | top6A | Type II DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (385 aa) |
| | top6B | Type II DNA topoisomerase VI, subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (567 aa) |
| | TK0800 | RNA-binding protein, containing KH domain. (238 aa) |
| | TK0830 | Hypothetical protein, conserved (N-terminus). (67 aa) |
| | nep1 | Ribosome biogenesis protein Nep1p homolog, suppressor Mra1 family; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (220 aa) |
| | rpl21e | LSU ribosomal protein L21E; Belongs to the eukaryotic ribosomal protein eL21 family. (98 aa) |
| | rpl35ae | LSU ribosomal protein L35AE; Belongs to the eukaryotic ribosomal protein eL33 family. (86 aa) |
| | rpl37e | LSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (63 aa) |
| | smc | Chromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1189 aa) |
| | TK1048 | ATPase, RecA superfamily. (232 aa) |
| | rps7 | SSU ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (215 aa) |
| | rps12 | SSU ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa) |
| | rpl30e | LSU ribosomal protein L30E; Belongs to the eukaryotic ribosomal protein eL30 family. (102 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (1229 aa) |
| | rpl44e | LSU ribosomal protein L44E; Binds to the 23S rRNA. (94 aa) |
| | rps27e | SSU ribosomal protein S27E. (65 aa) |
| | nop10 | RNA-binding protein, Nop10p family; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (59 aa) |
| | TK1190 | Predicted GTPase, containing NOG1 domain. (358 aa) |
| | rps8e | SSU ribosomal protein S8E. (130 aa) |
| | TK1199 | TBP-interacting protein Tip49 homolog. (440 aa) |
| | rps15 | SSU ribosomal protein S15P. (151 aa) |
| | rps3ae | SSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. (200 aa) |
| | rps19e | SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (150 aa) |
| | rpl24e | LSU ribosomal protein L24E; Binds to the 23S rRNA. (67 aa) |
| | rps28e | SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. (70 aa) |
| | rpl7ae | LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (125 aa) |
| | TK1312 | Hypothetical protein, conserved, containing V4R domain. (394 aa) |
| | rpl39e | LSU ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | rpl31e | LSU ribosomal protein L31E; Belongs to the eukaryotic ribosomal protein eL31 family. (90 aa) |
| | rpl18a | LSU ribosomal protein L20A. (77 aa) |
| | dnaG | DnaG-related protein, containing Toprim domain; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (464 aa) |
| | hpkA | Archaeal histone A; Binds and compacts DNA (about 120 base pairs per nucleosome, corresponding to four histone dimers) to form nucleosome-like structures. (67 aa) |
| | rpl12 | LSU ribosomal protein L12A; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (106 aa) |
| | rpl10 | LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (340 aa) |
| | rpl1 | LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (216 aa) |
| | rpl11 | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (165 aa) |
| | spt5 | Transcription antitermination protein; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (152 aa) |
| | rpl15e | LSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. (194 aa) |
| | rpl40e | LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa) |
| | rps2 | SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (201 aa) |
| | rps9 | SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (135 aa) |
| | rpl13 | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | rpl18e | LSU ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa) |
| | rps11 | SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (140 aa) |
| | rps4 | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa) |
| | rps13 | SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (149 aa) |
| | rpl14e | LSU ribosomal protein L14E; Belongs to the eukaryotic ribosomal protein eL14 family. (83 aa) |
| | rpl34e | LSU ribosomal protein L34E; Belongs to the eukaryotic ribosomal protein eL34 family. (90 aa) |
| | rpl15 | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa) |
| | rpl30 | LSU ribosomal protein L30P. (155 aa) |
| | rps5 | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (235 aa) |
| | rpl18 | LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (201 aa) |
| | rpl19e | LSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa) |
| | rpl32e | LSU ribosomal protein L32E; Belongs to the eukaryotic ribosomal protein eL32 family. (126 aa) |
| | rpl6 | LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa) |
| | rps8 | SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rps14 | SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (56 aa) |
| | rpl5 | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (183 aa) |
| | rps4e | SSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa) |
| | rpl24 | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (121 aa) |
| | rpl14 | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa) |
| | rps17 | SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (114 aa) |
| | rpl29 | LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (66 aa) |
| | rps3 | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (209 aa) |
| | rpl22 | LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (156 aa) |
| | rps19 | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (133 aa) |
| | rpl2 | LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (239 aa) |
| | rpl23 | LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl4 | LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (255 aa) |
| | rpl3 | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (346 aa) |
| | TK1543 | Hypothetical protein, conserved, DUF171 family. (256 aa) |
| | rpl10e | LSU ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family. (182 aa) |
| | TK1581 | Hypothetical protein, conserved, UPF0113 family. (169 aa) |
| | TK1590 | Predicted ATPase, AAA superfamily; Belongs to the UPF0273 family. (248 aa) |
| | TK1636 | Predicted exosome subunit, UPF0023 family. (236 aa) |
| | cetZ | Cell division GTPase; Involved in cell shape control; Belongs to the CetZ family. (380 aa) |
| | rps27ae | SSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. (57 aa) |
| | rps24e | SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (98 aa) |
| | TK1789 | ATPase, RecA superfamily. (249 aa) |
| | priL | Eukaryotic-type DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (400 aa) |
| | priS | Eukaryotic-type DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after p [...] (346 aa) |
| | cdc6 | Cell division control protein 6 homolog; Involved in regulation of DNA replication. (415 aa) |
| | TK1910 | ATPase, RecA superfamily. (237 aa) |
| | TK1915 | LSU ribosomal protein L41E. (37 aa) |
| | TK1926 | Hypothetical protein, conserved, DUF74 family; Belongs to the UPF0145 family. (113 aa) |
| | TK1932 | ATPase, RecA superfamily. (448 aa) |
| | TK1945 | Predicted nucleic acid-binding protein, containing PIN domain. (140 aa) |
| | rps6e | SSU ribosomal protein S6E; Belongs to the eukaryotic ribosomal protein eS6 family. (125 aa) |
| | TK2042 | ATPase, RecA superfamily. (233 aa) |
| | TK2103 | Hypothetical protein, conserved. (97 aa) |
| | mre11 | DNA repair exonuclease Rad32/Mre11 homolog; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (460 aa) |
| | rfcS | Replication factor C, small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (866 aa) |
| | rfcL | Replication factor C, large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (499 aa) |
| | TK2286 | snoRNP component, Gar1 homolog. (115 aa) |
| | hpkB | Archaeal histone B; Binds and compacts DNA (about 120 base pairs per nucleosome, corresponding to four histone dimers) to form nucleosome-like structures. (67 aa) |
| | rbcL | Ribulose 1,5-bisphosphate carboxylase/oxygenase, typeIII; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. (444 aa) |
| | rps17e | SSU ribosomal protein S17E; Belongs to the eukaryotic ribosomal protein eS17 family. (67 aa) |
