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| | TK0011 | Hypothetical protein, conserved, UPF0047 family. (140 aa) |
| | taw2 | Met-10+ like protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (278 aa) |
| | TK0125 | N-acetyltransferase, GNAT family. (169 aa) |
| | TK0126 | Predicted transcription regulator, containing DNA-binding HTH domain. (180 aa) |
| | tbp | Transcription initiation factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (190 aa) |
| | TK0134 | Probable acetylpolyamine aminohydrolase, histon deacetylase family. (334 aa) |
| | TK0170 | Endonuclease IV. (281 aa) |
| | TK0174 | Hypothetical protein, conserved, AMMECR1 family. (205 aa) |
| | TK0179 | Hypothetical protein, conserved, DUF35 family. (134 aa) |
| | TK0181 | 3-hydroxy-3-methylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa) |
| | flpA | snoRNP component, Fibrillarin homolog; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (226 aa) |
| | TK0184 | snoRNP component, Nop56p/58p homolog. (420 aa) |
| | pdxS | Pyridoxine/pyridoxal 5-phosphate biosynthesis protein, SOR/SNZ family; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (376 aa) |
| | TK0270 | Transketolase, N-terminal section. (219 aa) |
| | lysJ | N2-acetyl-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways. (362 aa) |
| | lysZ | N2-acetyl-aminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (251 aa) |
| | lysY | N2-acetyl-aminoadipyl-delta-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (330 aa) |
| | TK0283 | Homocitrate synthase. (361 aa) |
| | TK0288 | Phosphonate matabolism protein PhnP homolog, metallo-beta-lactamase superfamily. (249 aa) |
| | kptA | RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (180 aa) |
| | TK0338 | Predicted nucleotide kinase, related to CMP and AMP kinases; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (177 aa) |
| | TK0348 | Predicted membrane protease subunit, stomatin/prohibitin homolog. (268 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (284 aa) |
| | TK0494 | Bifunctional carboxypeptidase/aminoacylase. (384 aa) |
| | TK0497 | Met-10+ like protein. (331 aa) |
| | TK0503 | Hypothetical protein, conserved, cupin superfamily. (113 aa) |
| | TK0507 | Adenylate cyclase, class 2. (173 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate decarboxylase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (185 aa) |
| | TK0521 | DEAD/DEAH box RNA helicase, fused to C-terminal uncharacterized domain. (900 aa) |
| | TK0591 | Predicted N-acetyltransferase, GNAT family. (335 aa) |
| | TK0617 | U3 snoRNP component, archaeal imp4 homolog, containing Brix domain; Probably involved in the biogenesis of the ribosome. (208 aa) |
| | TK0627 | NapA-type sodium/hydrogen antiporter. (379 aa) |
| | ftsY | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (342 aa) |
| | TK0722 | Probable protein-S isoprenylcysteine O-methyltransferase. (143 aa) |
| | TK0730 | ABC-type transport system involved in Fe-S cluster assembly, permease component. (446 aa) |
| | tmcA | Predicted ATPase, DUF699 family, fused to acetyltransferase domain; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (811 aa) |
| | TK0774 | Predicted permease, auxin efflux carrier family. (292 aa) |
| | TK0784 | ERCC2/XPD/Rad3-related DNA repair helicase. (637 aa) |
| | top6A | Type II DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (385 aa) |
| | TK0810 | Oligosaccharyl transferase, STT3 subunit. (1000 aa) |
| | TK0815 | Peroxiredoxin, AhpC/TSA family. (148 aa) |
| | TK0868 | Probable bis(5'-adenosyl)-triphosphatase, HIT family. (163 aa) |
| | nep1 | Ribosome biogenesis protein Nep1p homolog, suppressor Mra1 family; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (220 aa) |
| | TK0884 | NapA-type sodium/hydrogen antiporter. (439 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (279 aa) |
| | TK0914 | 3-hydroxy-3-methylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (408 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (267 aa) |
| | TK0928 | Predicted DNA/RNA repair helicase. (461 aa) |
| | TK0959 | Hypothetical membrane protein, conserved, UPF0132 family. (121 aa) |
| | TK0971 | Hypothetical membrane protein, conserved, DUF125 family. (364 aa) |
| | TK0984 | alanyl-tRNA synthetase-related protein (partial). (215 aa) |
| | TK0994 | Arsenical pump-driving ATPase. (331 aa) |
| | TK1054 | N-acetyltransferase, GNAT family. (177 aa) |
| | TK1055 | Peroxiredoxin, bacterioferritin comigratory protein homolog, AhpC/TSA family. (154 aa) |
| | TK1088 | Geranylgeranyl hydrogenase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (395 aa) |
| | nop10 | RNA-binding protein, Nop10p family; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (59 aa) |
| | TK1113 | Predicted signaling protein, TraB family. (227 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (314 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (246 aa) |
| | TK1149 | methylmalonyl-CoA mutase, N-terminus of large subunit. (562 aa) |
| | TK1153 | Hypothetical protein, conserved. (288 aa) |
| | TK1179 | Adenylate cyclase, class 2. (183 aa) |
| | TK1190 | Predicted GTPase, containing NOG1 domain. (358 aa) |
| | rps8e | SSU ribosomal protein S8E. (130 aa) |
| | TK1208 | Glutaredoxin-related protein. (194 aa) |
| | TK1209 | Transmembrane electron transport protein. (242 aa) |
| | fen | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] (340 aa) |
| | TK1297 | Nonsense-mediated mRNA decay protein NMD3 homolog. (390 aa) |
| | TK1316 | Predicted membrane protease subunit, stomatin/prohibitin homolog. (317 aa) |
| | TK1324 | 4-hydroxybenzoate octaprenyltransferase. (264 aa) |
| | TK1326 | ferredoxin:NADP oxidoreductase, beta subunit. (291 aa) |
| | hel308 | RNA helicase Ski2 homolog; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (1125 aa) |
| | fni | Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (374 aa) |
| | rpl40e | LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa) |
| | rpl18e | LSU ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa) |
| | rps4 | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa) |
| | truB | tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (338 aa) |
| | rpl14e | LSU ribosomal protein L14E; Belongs to the eukaryotic ribosomal protein eL14 family. (83 aa) |
| | rps5 | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (235 aa) |
| | rps14 | SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (56 aa) |
| | TK1548 | Probable serine--glyoxylate aminotransferase, class V. (385 aa) |
| | TK1559 | NapA-type sodium/hydrogen antiporter. (380 aa) |
| | TK1560 | NapA-type sodium/hydrogen antiporter. (374 aa) |
| | TK1581 | Hypothetical protein, conserved, UPF0113 family. (169 aa) |
| | atpI | Archaeal/vacuolar-type H+-ATPase, subunit I; Produces ATP from ADP in the presence of a proton gradient across the membrane; Belongs to the V-ATPase 116 kDa subunit family. (663 aa) |
| | atpF | Archaeal/vacuolar-type H+-ATPase, subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (102 aa) |
| | atpB | Archaeal/vacuolar-type H+-ATPase, subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (465 aa) |
| | TK1607 | alanyl-tRNA synthetase-related protein (C-terminus). (406 aa) |
| | TK1630 | Hypothetical protein, conserved, containing ZPR1 zinc-finger domain. (234 aa) |
| | TK1639 | Probable bis(5'-adenosyl)-triphosphatase, HIT family. (155 aa) |
| | TK1685 | ferredoxin:NADP oxidoreductase, beta subunit. (284 aa) |
| | TK1703 | Signal peptidase I, fused to C-terminal uncharacterized domain. (355 aa) |
| | TK1718 | Oligosaccharyl transferase, STT3 subunit. (766 aa) |
| | TK1729 | Hypothetical membrane protein, conserved. (219 aa) |
| | TK1730 | Hypothetical membrane protein. (237 aa) |
| | glmA | exo-beta-D-glucosaminidase; Exo-type enzyme that specifically cleaves the non-reducing terminal glycosidic bond of chitooligosaccharides. Catalyzes the hydrolysis of GlcN- GlcNAc to glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). Involved in chitin degradation. Can also hydrolyze reduced chitobiose (GlcN2OH) and chitooligosaccharides of various chain lengths. (786 aa) |
| | dac | N-acetylchitobiose deacetylase; Deacylates the non-reducing end of diacetylchitobiose (GlcNAc2). Can also use N-acetylglucosamine (GlcNAc) and N- acetylchitotriose (GlcNAc3). Probably involved in chitin degradation. (267 aa) |
| | TK1768 | Glycogen synthase. (448 aa) |
| | TK1778 | Predicted hydrolase, metallo-beta-lactamase superfamily. (271 aa) |
| | pyrK | Probable dihydroorotate dehydrogenase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (233 aa) |
| | TK1810 | Cytidylyltransferase. (209 aa) |
| | TK1813 | NapA-type sodium/hydrogen antiporter. (396 aa) |
| | TK1817 | Cobalt/zinc/cadmium cation efflux pump protein. (286 aa) |
| | TK1836 | Geranylgeranyl hydrogenase. (371 aa) |
| | TK1846 | MoxR-related ATPase, AAA superfamily. (317 aa) |
| | TK1857 | GTPase, MMR1/HSR1 family. (357 aa) |
| | TK1878 | Alkylphosphonate utilization protein PhnP homolog, metallo-beta-lactamase superfamily. (258 aa) |
| | cdc6 | Cell division control protein 6 homolog; Involved in regulation of DNA replication. (415 aa) |
| | TK1912 | Aminopeptidase, family M28, containing PA domain. (561 aa) |
| | engB | Probable GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation. (183 aa) |
| | TK1956 | Hypothetical protein, conserved, containing ATP/GTP-binding site motif A; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA (By similarity). (351 aa) |
| | TK1957 | 4-hydroxybenzoate octaprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (277 aa) |
| | TK1961 | Replication factor A complex, RPA41 subunit. (356 aa) |
| | tfe | Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] (185 aa) |
| | TK2037 | Signal peptidase I. (164 aa) |
| | TK2063 | Hypothetical protein, conserved, cupin superfamily. (118 aa) |
| | TK2064 | Probable 2-methylthioadenine synthetase. (427 aa) |
| | hydG | Cytosolic NiFe-hydrogenase, gamma subunit. (294 aa) |
| | lig | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Can also use NAD, but less efficiently than ATP; Belongs to the ATP-dependent DNA ligase family. (562 aa) |
| | TK2198 | Hypothetical protein, conserved, UPF0047 family. (137 aa) |
| | endA | Archaeal tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (168 aa) |
| | TK2223 | Met-10+ like protein. (337 aa) |
| | radB | RadB recombinase; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity). (220 aa) |
| | TK2246 | L-asparaginase. (306 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (213 aa) |
| | TK2286 | snoRNP component, Gar1 homolog. (115 aa) |
