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hisF | Imidazoleglycerol-phosphate synthase, cyclase subunit F; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) | ||||
hisA | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino] imidazole-4-carboxamide isomerase. (233 aa) | ||||
TK0218 | Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (277 aa) | ||||
pdxS | Pyridoxine/pyridoxal 5-phosphate biosynthesis protein, SOR/SNZ family; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa) | ||||
guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa) | ||||
TK0852 | Hypothetical protein, conserved, radical SAM superfamily. (262 aa) | ||||
TK0720 | Hypothetical protein, conserved. (133 aa) | ||||
TK0703 | Hypothetical protein, conserved, radical SAM superfamily. (315 aa) | ||||
TK0675 | Hypothetical protein, conserved, radical SAM superfamily. (445 aa) | ||||
TK1574 | Histone acetyltransferase Elp3 homolog. (595 aa) | ||||
taw1 | Hypothetical protein, conserved, radical SAM superfamily; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (333 aa) | ||||
TK1676 | Nicotinate-nucleotide pyrophosphorylase. (390 aa) | ||||
TK1766 | Hypothetical protein, conserved, radical SAM superfamily. (361 aa) | ||||
TK1807 | Hypothetical protein, conserved, radical SAM superfamily. (302 aa) | ||||
deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. Could be involved in pentose biosynthesis. Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (224 aa) | ||||
TK2109 | Biotin synthase-related protein, radical SAM superfamily. (279 aa) | ||||
TK2114 | Hypothetical protein, conserved. (310 aa) | ||||
tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (226 aa) | ||||
TK2145 | Hypothetical protein, conserved, radical SAM superfamily. (590 aa) | ||||
TK2160 | Hypothetical protein, conserved, radical SAM superfamily. (443 aa) | ||||
moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (307 aa) | ||||
TK2248 | Biotin synthase-related protein, radical SAM superfamily. (312 aa) | ||||
pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. (302 aa) | ||||
pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (213 aa) | ||||
TK2299 | Anaerobic ribonucleoside-triphosphate reductase activating enzyme. (236 aa) | ||||
TK0475 | Bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase. (406 aa) | ||||
TK0290 | Pyruvate-formate lyase-activating enzyme. (306 aa) | ||||
TK0283 | Homocitrate synthase. (361 aa) | ||||
TK0268 | 2-dehydro-3-deoxyphosphoheptonate aldolase. (304 aa) | ||||
aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (213 aa) | ||||
trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (251 aa) | ||||
trpF | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (208 aa) | ||||
trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (227 aa) | ||||
TK0893 | Pyruvate fromate-lyase activating enzyme-related protein, radical SAM superfamily. (349 aa) | ||||
fba | DhnA-type fructose-1,6-bisphosphate aldolase; Belongs to the DeoC/FbaB aldolase family. (281 aa) | ||||
TK0990 | Oxaloacetate decarboxylase, alpha subunit. (595 aa) | ||||
TK1064 | Predicted metallocofactor modifying protein, radical SAM superfamily. (383 aa) | ||||
queE | Organic radical activating enzyme, radical SAM superfamily; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (253 aa) | ||||
TK1228 | Probable molybdenum cofactor biosynthesis protein A. (419 aa) | ||||
dapAL | Probable dihydrodipicolinate synthase; Belongs to the DapA family. (292 aa) | ||||
fni | Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (374 aa) |