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fen | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] (340 aa) | ||||
TK0914 | 3-hydroxy-3-methylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (408 aa) | ||||
pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (213 aa) | ||||
rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (228 aa) | ||||
TK0664 | Hypoxanthine/guanine phosphoribosyltransferase. (215 aa) |