13 items (Thermococcus kodakarensis) - STRING interaction network

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	coaBC	Phosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)
	pdaD	Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family. (157 aa)
	panB	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (284 aa)
	pyrF	Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (213 aa)
	TK2192	dephospho-CoA kinase. (195 aa)
	coaD	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. (165 aa)
	TK1968	2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor. (309 aa)
	Pk-chiA	Chitinase, containing dual catalytic domains. (1215 aa)
	TK1697	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor. (177 aa)
	rps24e	SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. (98 aa)
	rps27ae	SSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. (57 aa)
	TK1334	dephospho-CoA kinase; Belongs to the UPF0200 family. (185 aa)
	TK0895	S-layer protein precursor. (612 aa)

Your Current Organism:

Thermococcus kodakarensis

NCBI taxonomy Id: 69014
Other names: Pyrococcus sp. (strain KOD1), Pyrococcus sp. KOD1, T. kodakarensis KOD1, Thermococcus kodakaraensis KOD1, Thermococcus kodakarensis KOD1, Thermococcus kodakarensis str. KOD1, Thermococcus kodakarensis strain KOD1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Pk-chiA	TK0895	TK1765	TK0895	Chitinase, containing dual catalytic domains.	S-layer protein precursor.	0.701
Pk-chiA	pyrF	TK1765	TK2276	Chitinase, containing dual catalytic domains.	Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.563
TK0895	Pk-chiA	TK0895	TK1765	S-layer protein precursor.	Chitinase, containing dual catalytic domains.	0.701
TK0895	TK1697	TK0895	TK1697	S-layer protein precursor.	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	0.554
TK0895	pdaD	TK0895	TK0149	S-layer protein precursor.	Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family.	0.779
TK0895	pyrF	TK0895	TK2276	S-layer protein precursor.	Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.562
TK1334	TK1697	TK1334	TK1697	dephospho-CoA kinase; Belongs to the UPF0200 family.	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	0.826
TK1334	TK1968	TK1334	TK1968	dephospho-CoA kinase; Belongs to the UPF0200 family.	2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor.	0.718
TK1334	coaBC	TK1334	TK0517	dephospho-CoA kinase; Belongs to the UPF0200 family.	Phosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.	0.783
TK1334	coaD	TK1334	TK2128	dephospho-CoA kinase; Belongs to the UPF0200 family.	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.	0.743
TK1334	panB	TK1334	TK0363	dephospho-CoA kinase; Belongs to the UPF0200 family.	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.	0.710
TK1697	TK0895	TK1697	TK0895	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	S-layer protein precursor.	0.554
TK1697	TK1334	TK1697	TK1334	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	dephospho-CoA kinase; Belongs to the UPF0200 family.	0.826
TK1697	TK1968	TK1697	TK1968	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	2-dehydropantoate 2-reductase; Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. Prefers NADH rather than NADPH as the electron donor.	0.634
TK1697	TK2192	TK1697	TK2192	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	dephospho-CoA kinase.	0.976
TK1697	coaBC	TK1697	TK0517	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	Phosphopantothenoylcysteine synthetase/decarboxylase; Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.	0.644
TK1697	coaD	TK1697	TK2128	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.	0.978
TK1697	panB	TK1697	TK0363	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.	0.632
TK1697	pdaD	TK1697	TK0149	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family.	0.435
TK1697	pyrF	TK1697	TK2276	Hypothetical protein, conserved, DUF359 family; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). Can also use UTP, with lower efficiency and has weak activity with ATP, but shows a strong preference for GTP as the phosphate donor.	Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.479

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