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A0A1L9WEP1 A0A1L9WEP1 A0A1L9WGE6 A0A1L9WGE6 A0A1L9WI19 A0A1L9WI19 A0A1L9WLR0 A0A1L9WLR0 A0A1L9WM34 A0A1L9WM34 A0A1L9WMM5 A0A1L9WMM5 A0A1L9WNY0 A0A1L9WNY0 A0A1L9WNY6 A0A1L9WNY6 A0A1L9WNZ7 A0A1L9WNZ7 A0A1L9WSD4 A0A1L9WSD4 A0A1L9WT07 A0A1L9WT07 A0A1L9WT80 A0A1L9WT80 A0A1L9WTA2 A0A1L9WTA2 A0A1L9WTS9 A0A1L9WTS9 A0A1L9WTW5 A0A1L9WTW5 A0A1L9WU82 A0A1L9WU82 A0A1L9WU90 A0A1L9WU90 A0A1L9WU92 A0A1L9WU92 A0A1L9WWQ8 A0A1L9WWQ8 A0A1L9WXK0 A0A1L9WXK0 A0A1L9WXM6 A0A1L9WXM6 FEN1 FEN1 A0A1L9WXS7 A0A1L9WXS7 A0A1L9WY05 A0A1L9WY05 A0A1L9WY83 A0A1L9WY83 A0A1L9WYK2 A0A1L9WYK2 A0A1L9WZN4 A0A1L9WZN4 A0A1L9X199 A0A1L9X199 A0A1L9X1X6 A0A1L9X1X6 A0A1L9X3Y9 A0A1L9X3Y9 A0A1L9X5D4 A0A1L9X5D4 A0A1L9X5K4 A0A1L9X5K4 A0A1L9X634 A0A1L9X634 A0A1L9X6I9 A0A1L9X6I9 A0A1L9X6Q7 A0A1L9X6Q7 A0A1L9X891 A0A1L9X891 A0A1L9X8D3 A0A1L9X8D3 A0A1L9X8U4 A0A1L9X8U4 A0A1L9X927 A0A1L9X927 A0A1L9X972 A0A1L9X972 A0A1L9X9R1 A0A1L9X9R1 A0A1L9XA54 A0A1L9XA54
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1L9WEP1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (605 aa)
A0A1L9WGE6Uncharacterized protein. (770 aa)
A0A1L9WI19Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2462 aa)
A0A1L9WLR0Uncharacterized protein. (390 aa)
A0A1L9WM34Checkpoint protein; Belongs to the HUS1 family. (381 aa)
A0A1L9WMM5AAA domain-containing protein. (352 aa)
A0A1L9WNY0AAA_23 domain-containing protein. (1301 aa)
A0A1L9WNY6Uncharacterized protein. (77 aa)
A0A1L9WNZ7Uncharacterized protein. (384 aa)
A0A1L9WSD4Pectinesterase; Involved in maceration and soft-rotting of plant tissue. (327 aa)
A0A1L9WT07Uncharacterized protein. (766 aa)
A0A1L9WT80AAA domain-containing protein. (389 aa)
A0A1L9WTA2Uncharacterized protein. (343 aa)
A0A1L9WTS9DUF1767 domain-containing protein. (255 aa)
A0A1L9WTW5EthD domain-containing protein. (162 aa)
A0A1L9WU82Rad51 domain-containing protein. (326 aa)
A0A1L9WU90AAA domain-containing protein. (972 aa)
A0A1L9WU92UmuC domain-containing protein. (664 aa)
A0A1L9WWQ8Uncharacterized protein. (440 aa)
A0A1L9WXK0AAA domain-containing protein. (352 aa)
A0A1L9WXM6Vezatin domain-containing protein. (614 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
A0A1L9WXS7Replication factor C subunit 1. (1060 aa)
A0A1L9WY05Uncharacterized protein. (1118 aa)
A0A1L9WY83Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (258 aa)
A0A1L9WYK2Uncharacterized protein. (978 aa)
A0A1L9WZN4Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2897 aa)
A0A1L9X199Uncharacterized protein. (1541 aa)
A0A1L9X1X6Uncharacterized protein. (613 aa)
A0A1L9X3Y9DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (623 aa)
A0A1L9X5D4DNA ligase. (879 aa)
A0A1L9X5K4Uncharacterized protein. (543 aa)
A0A1L9X634ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (561 aa)
A0A1L9X6I9BRCT domain-containing protein. (1849 aa)
A0A1L9X6Q7Uncharacterized protein. (155 aa)
A0A1L9X891RPA_C domain-containing protein. (268 aa)
A0A1L9X8D3Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (821 aa)
A0A1L9X8U4AAA domain-containing protein. (392 aa)
A0A1L9X927RECA_2 domain-containing protein. (704 aa)
A0A1L9X972Uncharacterized protein. (551 aa)
A0A1L9X9R1DNA ligase. (834 aa)
A0A1L9XA543'-5' exonuclease domain-containing protein. (281 aa)
Your Current Organism:
Aspergillus aculeatus
NCBI taxonomy Id: 690307
Other names: A. aculeatus ATCC 16872, Aspergillus aculeatus ATCC 16872
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